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New technique improves accuracy of CRISPR/Cas9 gene editing system

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.

19 Nov 2015

New insulin pill shows promise as novel form of therapy for diabetes

An insulin pill being developed by researchers at UC Santa Barbara may in the near future give another blood sugar management option to those who suffer from diabetes. The novel drug delivery technology may also apply to a wide spectrum of other therapies.

19 Nov 2015

Role of biomarkers in drug development and regulatory decision making

Biomarkers in Medicine, a leading MEDLINE-indexed journal, has published a special focus issue exploring the increasingly important role of biomarkers in both drug development and regulatory decision making.

19 Nov 2015

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

Two women, seated at a table, told their stories in quiet tones. A group of chefs, some standing, others seated, leaned forward eagerly, clearly interested in what these two women had to say. They peppered the women with questions: did food taste better cold or hot? Was texture an issue? Did a glass of wine before dinner help or hurt the flavor experience? The women have taken chemotherapy for their cancer. One of them -- Gina Mullin -- will be taking chemotherapy every three weeks for the rest of her life. Both of them tell heartbreaking stories about a side effect of chemotherapy that gets swept under the rug: food tastes terrible.

19 Nov 2015

Sound deprivation causes irreversible damage to the inner ear

Massachusetts Eye and Ear investigators have shown that sound deprivation in adult mice causes irreversible damage to the inner ear. The findings, published in PLOS ONE, suggest that chronic conductive hearing loss, such as that caused by recurrent ear infections, leads to permanent hearing impairment if it remains untreated.

19 Nov 2015

Dartmouth study reveals the brain's visual pathways

A Dartmouth study reveals how the brain understands motion and still objects to help us navigate our complex visual world.

19 Nov 2015

IMB scientists unravel complex regulatory mechanism involved in brain development

Scientists at the Institute of Molecular Biology in Mainz have unraveled a complex regulatory mechanism that explains how a single gene can drive the formation of brain cells. The research, published in The EMBO Journal, is an important step towards a better understanding of how the brain develops. It also harbors potential for regenerative medicine.

19 Nov 2015

New study finds link between obesity and surgery risk in orthopaedic trauma patients

A new study appearing in the November 18 issue of the Journal of Bone & Joint Surgery found a link between obesity and a higher risk for surgery in orthopaedic trauma patients. In addition, researchers found that patients with obesity had longer hospital stays and greater treatment costs. They were also more likely to be discharged to a care facility, rather than to home.

19 Nov 2015

International task force aims to develop new approach to cancer prevention and treatment

Advancements in precision medicine have led to many new targeted cancer therapies for cancer patients. These treatments focus on using agents that target one or two genes that contribute to tumor development. The approach tends to be more effective against cancer cells and less toxic toward normal cells than standard chemotherapeutic regimens.

19 Nov 2015

IQWiG finds no added benefit for insulin degludec/liraglutide in adults with type 2 diabetes

The fixed combination of the two drugs insulin degludec and liraglutide (trade name: Xultophy) has been approved since June 2015 also in adults with type 2 diabetes mellitus when oral antidiabetics (OADs) combined with a GLP-1 receptor agonist do not provide adequate glycaemic control. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether this fixed combination offers an added benefit over the appropriate comparator therapy (ACT).

19 Nov 2015

New article examines women's perceptions of relationship in Fifty Shades of Grey

Examining women's perceptions of the relationship between Christian and Anastasia in the popular movie Fifty Shades of Grey is a safe and valuable way to discuss healthy and unhealthy relationship dynamics, including the warning signs of intimate partner violence. Young women expressed mixed views, describing parts of the movie relationship as exciting and romantic and other aspects as controlling, manipulative, and emotionally abusive in a new study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

19 Nov 2015

HIV+ individuals show deficits in cognitive functioning

Neuroscientists at Georgetown University Medical Center have found in a small study that although a group of HIV+ older individuals scored "cognitively normal" in standard neuropsychology testing, a scan of their brains tells a different story.

19 Nov 2015

Infants are capable of deductive problem solving before age one, new study reveals

Human infants are capable of deductive problem solving as early as 10 months of age, a new study by psychologists at Emory University and Bucknell finds. The journal Developmental Science is publishing the research, showing that babies can make transitive inferences about a social hierarchy of dominance.

19 Nov 2015

NIAID launches major initiative to advance novel approaches to treat, prevent HIV infections

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, launched a major initiative to advance novel approaches to treat and prevent HIV infections based on broadly neutralizing antibodies (bNAbs) today.

19 Nov 2015

College courses may increase cognitive capacity, reduce debilitating effects of dementia for older adults

Older adults who take college courses may increase their cognitive capacity and possibly reduce their risk for developing Alzheimer's disease or other forms of dementia, according to new research published by the American Psychological Association.

19 Nov 2015

Higher levels of air pollution in major urban areas linked to heart attack risks in people 65 and older

Researchers from the Johns Hopkins Bloomberg School of Public Health have found a link between higher levels of a specific kind of air pollution in major urban areas and an increase in cardiovascular-related hospitalizations such as for heart attacks in people 65 and older.

18 Nov 2015

Potential treatment strategy for glycogen storage disease

Researchers from the Duke-NUS Graduate Medical School Singapore and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease.

18 Nov 2015

Georgia State University researchers develop a method to better trace and treat cancer

A method to better trace changes in cancers and treatment of the prostate and lung without the limitations associated with radiation has been developed by Georgia State University researchers.

18 Nov 2015

Gamma interferon may have potential to prevent Ebola infection

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers and local populations in the event of future outbreaks.

18 Nov 2015

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the official initiation of construction for its cell and gene therapy manufacturing centre.

18 Nov 2015

Medical Research News

New technique improves accuracy of CRISPR/Cas9 gene editing system

New insulin pill shows promise as novel form of therapy for diabetes

Role of biomarkers in drug development and regulatory decision making

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

Sound deprivation causes irreversible damage to the inner ear

Dartmouth study reveals the brain's visual pathways

IMB scientists unravel complex regulatory mechanism involved in brain development

New study finds link between obesity and surgery risk in orthopaedic trauma patients

International task force aims to develop new approach to cancer prevention and treatment

IQWiG finds no added benefit for insulin degludec/liraglutide in adults with type 2 diabetes

New article examines women's perceptions of relationship in Fifty Shades of Grey

HIV+ individuals show deficits in cognitive functioning

Infants are capable of deductive problem solving before age one, new study reveals

NIAID launches major initiative to advance novel approaches to treat, prevent HIV infections

College courses may increase cognitive capacity, reduce debilitating effects of dementia for older adults

Higher levels of air pollution in major urban areas linked to heart attack risks in people 65 and older

Potential treatment strategy for glycogen storage disease

Georgia State University researchers develop a method to better trace and treat cancer

Gamma interferon may have potential to prevent Ebola infection

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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