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Adaptive, light-activated nanotherapy effective against drug-resistant bacteria

In the ever-escalating evolutionary battle with drug-resistant bacteria, humans may soon have a leg up thanks to adaptive, light-activated nanotherapy developed by researchers at the University of Colorado Boulder.

19 Jan 2016

Regular physical activity improves cardiovascular health, lowers mortality risk

The majority of citizens in developed countries should not be concerned by potential harm from exercise but rather by the lack of exercise in their lives, according to a clinical perspective published today in the Journal of the American College of Cardiology from the ACC Sports and Exercise Cardiology Leadership Council.

19 Jan 2016

Extended weekend sleep can counteract increased risk of diabetes associated with sleep loss

Two consecutive nights of extended sleep, a typical weekend occurrence, appears to counteract the increased risk of diabetes associated with short-term sleep restriction during the work week, at least in lean, healthy, young men eating a controlled diet.

19 Jan 2016

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites.

19 Jan 2016

Insulet donates $10,000 each to ADA and JDRF to improve lives of people living with diabetes

Insulet Corporation, the leader in tubeless insulin pump technology with its OmniPod Insulin Management System, today announced that is has donated $10,000 each to the American Diabetes Association and the Juvenile Diabetes Research Foundation.

19 Jan 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

Johns Hopkins study shows high doses of cocaine kill brain cells

Working with mice, researchers at Johns Hopkins have contributed significant new evidence to support the idea that high doses of cocaine kill brain cells by triggering overactive autophagy, a process in which cells literally digest their own insides. Their results, moreover, bring with them a possible antidote, an experimental compound dubbed CGP3466B.

19 Jan 2016

New clinical imaging method may enable doctors to tackle lung infections

A new clinical imaging method developed in collaboration with a University of Exeter academic may enable doctors to tackle one of the main killers of patients with weakened immune systems sooner and more effectively.

19 Jan 2016

New study finds that living in high-rise buildings may affect survival after cardiac arrest

The number of people living in high-rise buildings in rising, but along with the convenience and panoramic views of a downtown condo comes a risk: a new study found that survival rates from cardiac arrest decrease the higher up the building a person lives.

19 Jan 2016

Researchers identify protein structure linked to pain and heat perception

Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!"

19 Jan 2016

Combination of PARP inhibitors and c-MET may benefit breast cancer patients

Findings from a new study reveal that PARP inhibitors, an emerging class of drugs being studied in cancer clinical trials, may be enhanced by combining them with inhibitors targeting an oncogene known as c-MET which is overexpressed in many cancers.

19 Jan 2016

TSRI scientists discover molecular ‘switch’ that could reduce nicotine addiction

Scientists at The Scripps Research Institute have discovered that a lipid in brain cells may act as a “switch” to increase or decrease the motivation to consume nicotine.

19 Jan 2016

Concussions related to sports and recreation activities affect millions of Americans

Every year, between 3 million and 4 million Americans suffer concussions in sports and recreation. Head impacts and concussions caused by contact sports are a quickly growing epidemic among young athletes.

19 Jan 2016

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

We've all seen the headlines. "Man found to be shedding virulent strain of polio"; "Virulent flu strain in Europe hits the economy"; "Most virulent strain of E. coli ever seen contains DNA sequences from plague bacteria."

19 Jan 2016

NIST researchers simulate new method for fast, precise DNA sequencing

Researchers at the National Institute of Standards and Technology (NIST) have simulated a new concept for rapid, accurate gene sequencing by pulling a DNA molecule through a tiny, chemically activated hole in graphene--an ultrathin sheet of carbon atoms--and detecting changes in electrical current.

19 Jan 2016

Mount Sinai Heart starts TANSNIP-PESA study to determine how workplace-based lifestyle intervention reduces CV risk

World-renowned cardiologist Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, is undertaking a three-year study, known as the TANSNIP-PESA study, to determine whether a workplace-based lifestyle intervention, accompanied by imaging data, will lead to a reduction in the prevalence of cardiovascular (CV) disease risk factors related to lifestyle.

19 Jan 2016

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New blood biomarkers reflecting vasoreactivity in lung blood vessels of patients with heart- and lung disease, can lead to simplified diagnostics and better evaluation of treatment for patients with the condition pulmonary arterial hypertension (PAH).

18 Jan 2016

Medical Research News

Adaptive, light-activated nanotherapy effective against drug-resistant bacteria

Regular physical activity improves cardiovascular health, lowers mortality risk

Extended weekend sleep can counteract increased risk of diabetes associated with sleep loss

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

Insulet donates $10,000 each to ADA and JDRF to improve lives of people living with diabetes

Researchers suggest ways to make TB drugs more efficacious against mutations

Johns Hopkins study shows high doses of cocaine kill brain cells

New clinical imaging method may enable doctors to tackle lung infections

New study finds that living in high-rise buildings may affect survival after cardiac arrest

Researchers identify protein structure linked to pain and heat perception

Combination of PARP inhibitors and c-MET may benefit breast cancer patients

TSRI scientists discover molecular ‘switch’ that could reduce nicotine addiction

Concussions related to sports and recreation activities affect millions of Americans

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

NIST researchers simulate new method for fast, precise DNA sequencing

Mount Sinai Heart starts TANSNIP-PESA study to determine how workplace-based lifestyle intervention reduces CV risk

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New method helps generate cardiac cells for heart disease studies, drug discovery

Researchers confirm that cranberry extract helps fight UTIs in breastfed children under age one

Specialized oral nutrition supplement associated with 50% lower death rate in older patients

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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