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Mayo Clinic-led researchers combine genetic variants to improve identification of women with breast cancer

Recent large-scale genomic analyses have uncovered dozens of common genetic variants that are associated with breast cancer. Each variant, however, contributes only a tiny amount to a person's overall risk of developing the disease.

6 Apr 2015

Simple test outperforms current standard test for early-stage prostate cancer

A test that costs less than a $1 and yields results in minutes has been shown in newly published studies to be more sensitive and more exact than the current standard test for early-stage prostate cancer.

6 Apr 2015

New approach could help identify novel drug targets to combat lethal fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal agents.

6 Apr 2015

Combination of signaling molecules can inhibit growth of breast cancer cells

Researchers at UT Southwestern Medical Center have uncovered how the body's inflammatory response can alter how estrogen promotes the growth of breast cancer cells.

6 Apr 2015

Case Western Reserve researchers explore ways to treat, cure TB

After discovering a unique group of people resistant to tuberculosis (TB) infection, Case Western Reserve researchers are leading an international team dedicated to understanding exactly how they fight off a disease that claims 1.5 million lives each year.

6 Apr 2015

U-M's Taubman Institute receives $3 million gift to support next generation of medical research

A $3 million gift from noted business and philanthropic leaders Leslie and Abigail Wexner will support the next generation of medical research trailblazers at the University of Michigan through grants from the A. Alfred Taubman Medical Research Institute.

6 Apr 2015

High status gestures assumed to stimulate psychological, physiological processes

Hands pressed to the hips or perhaps leaning back with arms crossed behind the head are typical poses of power. Referred to power poses or high status gestures in technical jargon, they are assumed to stimulate both psychological and physiological processes.

3 Apr 2015

Adolescent binge-drinking alters genes needed for normal brain maturation

Binge-drinking during adolescence may perturb brain development at a critical time and leave lasting effects on genes and behavior that persist into adulthood.

3 Apr 2015

Research reveals two critical windows to turn around junk food addiction

University of Adelaide researchers have shown there are two critical windows during the developmental pathway to adulthood when exposure to junk food is most harmful, particularly for female offspring.

3 Apr 2015

Peripheral inflammatory cells play role in Parkinson's disease

A small area in the midbrain known as the substantia nigra is the control center for all bodily movement. Increasing loss of dopamine-generating neurons in this part of the brain therefore leads to the main symptoms of Parkinson's disease - slowness of movement, rigidity and shaking.

3 Apr 2015

Mouse model may help understand the physiology behind complex brain disorders

Complex brain disorders, such as autism or schizophrenia, still puzzle scientists because their causes lie hidden in early events of brain development, which are still poorly understood.

3 Apr 2015

A new amyloid-targeting treatment for Alzheimer's disease

With each new amyloid-targeting treatment for Alzheimer's disease that has been developed, there has been a corresponding concern. For example, antibodies targeting amyloid-β peptide (Aβ) produce inflammation in the brain in some patients.

3 Apr 2015

Microbes go dormant in the presence of SSV9 virus

The microbes could surrender to the harmless virus, but instead freeze in place, dormant, waiting for their potential predator to go away, according to a recent study in mBio.

3 Apr 2015

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

All living things--from dandelions to reindeer--evolve over time. Cancer cells are no exception, and are subject to the two overarching mechanisms described by Charles Darwin: chance mutation and natural selection.

3 Apr 2015

Research shows that hippocampus is dedicated to memory formation, not to spatial skills

In work that reconciles two competing views of brain structures involved in memory and spatial perception, researchers at University of California, San Diego School of Medicine have conducted experiments that suggest the hippocampus - a small region in the brain's limbic system - is dedicated largely to memory formation and not to spatial skills, such as navigation.

3 Apr 2015

Symptoms of depression, insomnia are risk factors for frequent nightmares, study suggests

A new study suggests that symptoms of depression and insomnia are the strongest predictors of having frequent nightmares.

3 Apr 2015

NASH patients more likely to have increased intestinal permeability, shows study

Non-alcoholic steatohepatitis (NASH), the more severe form of non-alcoholic fatty liver disease (NAFLD) that can progress to liver fibrosis and cirrhosis, is associated with leakiness of the intestinal wall, which in turn may worsen liver disease, according to research published in Cellular and Molecular Gastroenterology and Hepatology, the new basic science journal of the American Gastroenterological Association.

3 Apr 2015

MRSA bacteria exposed to cigarette smoke become more resistant to antimicrobial peptides

Methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant superbug, can cause life-threatening skin, bloodstream and surgical site infections or pneumonia. Researchers at the University of California, San Diego School of Medicine now report that cigarette smoke may make matters worse.

3 Apr 2015

Researchers examine effects of aging on older people with autism

Researchers at Barrow Neurological Institute at Dignity Health St. Joseph's Hospital and Medical Center are conducting a unique study on the effects of aging on older people who have Autism.

3 Apr 2015

Pseudogenes may play role in cancer development, shows study

Pseudogenes, a sub-class of long non-coding RNA (lncRNA) that developed from the genome's 20,000 protein-coding genes but lost the ability to produce proteins, have long been considered nothing more than genomic "junk." Yet the retention of these 20,000 mysterious remnants during evolution has suggested that they may in fact possess biological functions and contribute to the development of disease.

3 Apr 2015

Medical Research News

Mayo Clinic-led researchers combine genetic variants to improve identification of women with breast cancer

Simple test outperforms current standard test for early-stage prostate cancer

New approach could help identify novel drug targets to combat lethal fungal infections

Combination of signaling molecules can inhibit growth of breast cancer cells

Case Western Reserve researchers explore ways to treat, cure TB

U-M's Taubman Institute receives $3 million gift to support next generation of medical research

High status gestures assumed to stimulate psychological, physiological processes

Adolescent binge-drinking alters genes needed for normal brain maturation

Research reveals two critical windows to turn around junk food addiction

Peripheral inflammatory cells play role in Parkinson's disease

Mouse model may help understand the physiology behind complex brain disorders

A new amyloid-targeting treatment for Alzheimer's disease

Microbes go dormant in the presence of SSV9 virus

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

Research shows that hippocampus is dedicated to memory formation, not to spatial skills

Symptoms of depression, insomnia are risk factors for frequent nightmares, study suggests

NASH patients more likely to have increased intestinal permeability, shows study

MRSA bacteria exposed to cigarette smoke become more resistant to antimicrobial peptides

Researchers examine effects of aging on older people with autism

Pseudogenes may play role in cancer development, shows study

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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