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Researchers find protein that plays crucial role in development of allergic airway inflammation

Allergies are becoming more commonplace, particularly in industrialised coun-tries. In addition to hay fever, allergic asthma is currently considered to be one of the most widespread allergies. UFZ researchers and their colleagues from the University of Leipzig have recently been successful in finding a protein that plays a critical role in the development of allergic airway inflammation.

12 Oct 2015

Stem cell research to help combat congenital brittle bone disease

A study involving researchers from the Department of Genetics at the University of Leicester is to be conducted for the first time involving the transplantation of stem cells into foetuses with the brittle-bone disease osteogenesis imperfecta (OI), which causes repeated fractures, often before birth.

12 Oct 2015

Study: Nurses can play pivotal role in helping reduce smoking rates in China

China has a big smoking problem. Three-hundred-fifty million Chinese people smoke and 1 million deaths a year in China are attributed to smoking-related illnesses. By 2020, that's expected to double to 2 million Chinese people dying annually from using tobacco.

12 Oct 2015

Human malaria parasite molecules share key gene segments with chimp, gorilla malaria parasites

The malaria parasite molecules associated with severe disease and death--those that allow the parasite to escape recognition by the immune system--have been shown to share key gene segments with chimp and gorilla malaria parasites, which are separated by several millions of years, according to a new study led by Harvard T.H. Chan School of Public Health.

12 Oct 2015

Researchers reveal 3-D structure of biologically active DNA

Using a multidisciplinary approach, researchers, led by those at Baylor College of Medicine, revealed in unprecedented detail the three-dimensional structure of biologically active DNA. A report on their work appears online in the journal Nature Communications.

12 Oct 2015

Lithium can be safe, effective for children suffering from bipolar disorder

A multicenter study of young patients with bipolar disorder provides what may be the most scientifically rigorous demonstration to date that lithium -- a drug used successfully for decades to treat adults with the condition -- can also be safe and effective for children suffering from it.

12 Oct 2015

Exposure to acrylamide through STP use much smaller than exposure from diet or cigarette smoking

The first comprehensive assessment of the acrylamide content of smokeless tobacco products (STPs) has shown that exposure to acrylamide through STP use is much smaller than --approximately 1% of -- exposure from the diet or from cigarette smoking.

12 Oct 2015

York scientists target specific sodium channel to prevent breast cancer

Scientists at the University of York, using clinical specimens from charity Breast Cancer Now's Tissue Bank, have conducted new research into a specific sodium channel that indicates the presence of cancer cells and affects tumour growth rates.

12 Oct 2015

People often end up in emergency room because of infection-related falls

People who end up in the emergency room because of a fall often are tripped up by an infection, rather than a loose throw rug or poor eyesight, suggests a study being presented at IDWeek 2015.

12 Oct 2015

Antiviral agent protects rhesus monkeys from deadly Ebola virus

Rhesus monkeys were completely protected from the deadly Ebola virus when treated three days after infection with a compound that blocks the virus's ability to replicate. These encouraging preclinical results suggest the compound, known as GS-5734, should be further developed as a potential treatment, according to research findings to be presented tomorrow at the IDWeek conference.

12 Oct 2015

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Chronic pain results from disease or trauma to the nervous system. Damaged nerve fibres with heightened responses to normal stimuli send incorrect messages to pain centres in the brain. This phenomenon, called "peripheral and central sensitization" is one of the key mechanisms involved in the condition which touches people with diabetes, cancer, and those suffering from multiple sclerosis, among others.

12 Oct 2015

UV robots help reduce rates of C. diff transmission among cancer inpatients

Robots are capable of all sorts of tasks to help better treat cancer: They connect oncologists to patients remotely, make incisions, staple them shut, deliver "nano" therapies--and they clean rooms. New research from Penn Medicine infection control specialists found that ultraviolet (UV) robots helped reduce the rates transmission of the common bacterial infection known as Clostridium difficile among cancer inpatients - mostly blood cancer patients, a group more vulnerable to hospital-acquired infections - by 25 percent. The interventions also saved about $150,000 in annual direct medical costs.

12 Oct 2015

Glycan binding proteins modify parasite infection in cells of the heart muscle

Chagas disease is the main cause of infectious heart disease in Latin America. Researchers from the INGEBI and IBYME Institutes in Argentina explored the effect of glycan binding protein interactions between the human host and Typanosoma cruzi parasite. They found that a glycan binding protein expressed in humans modified the infection in cells of the heart muscle, showing the importance of galectins in the response to parasite infection.

12 Oct 2015

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS). This is the first demonstration that introduction of blood in the healthy brain is sufficient to cause peripheral immune cells to enter the brain, which then go on to cause brain damage.

12 Oct 2015

UConn researchers sequence RNA of most complicated gene

UConn researchers have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone.

From Oxford Nanopore Technologies 12 Oct 2015

Novel mathematical method may help reduce development of antibiotic-resistant bacteria

It is estimated that each year in the United States 2 million people become infected with bacteria that are resistant to one or more types of antibiotics, and at least 23,000 people will die because of these infections. This problem is being exacerbated by overuse of antibiotics for livestock and also in community clinical practice. This overuse, combined with the slow pace of novel drug discovery is a growing threat to public health.

12 Oct 2015

YK-4-279 compound works against some forms of leukemia: Study

A compound discovered and developed by a team of Georgetown Lombardi Comprehensive Cancer Center researchers that halts cancer in animals with Ewing sarcoma and prostate cancer appears to work against some forms of leukemia, too.

12 Oct 2015

Magnet hospitals have higher patient ratings of care than other hospitals

Patients' experience with healthcare has become the focal point for quality improvement among hospitals and care providers. The Affordable Care Act incentivizes hospitals to improve patient satisfaction by paying a financial incentive to hospitals that achieve high ratings from patients.

12 Oct 2015

Many early-stage breast cancer patients still not getting life-saving treatment, new study finds

Accelerated partial breast irradiation was designed to be a faster, more convenient, and potentially safer way for many women with breast cancer to reduce their mortality risk and help keep their cancer from returning after surgery. But a new study shows that the availability of the approach is failing to reduce the percentage of early-stage breast cancer patients who do not receive the radiation treatment that could save their lives.

12 Oct 2015

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Scientists are now better able to predict how quickly the HIV virus will return after individuals stop treatment following a discovery by researchers at UNSW Australia and the University of Oxford.

12 Oct 2015

Medical Research News

Researchers find protein that plays crucial role in development of allergic airway inflammation

Stem cell research to help combat congenital brittle bone disease

Study: Nurses can play pivotal role in helping reduce smoking rates in China

Human malaria parasite molecules share key gene segments with chimp, gorilla malaria parasites

Researchers reveal 3-D structure of biologically active DNA

Lithium can be safe, effective for children suffering from bipolar disorder

Exposure to acrylamide through STP use much smaller than exposure from diet or cigarette smoking

York scientists target specific sodium channel to prevent breast cancer

People often end up in emergency room because of infection-related falls

Antiviral agent protects rhesus monkeys from deadly Ebola virus

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

UV robots help reduce rates of C. diff transmission among cancer inpatients

Glycan binding proteins modify parasite infection in cells of the heart muscle

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

UConn researchers sequence RNA of most complicated gene

Novel mathematical method may help reduce development of antibiotic-resistant bacteria

YK-4-279 compound works against some forms of leukemia: Study

Magnet hospitals have higher patient ratings of care than other hospitals

Many early-stage breast cancer patients still not getting life-saving treatment, new study finds

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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