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Absence of vision from birth leads to permanent state of pain hypersensitivity, shows report

Absence of vision from birth leads to a permanent state of pain hypersensitivity, reports PAIN. An international team of scientists investigated whether congenitally blind subjects experience pain differently than sighted individuals. Their results, published in the current issue of PAIN®, reveal compelling evidence that congenitally blind individuals are hypersensitive to pain caused by thermal stimuli.

3 Nov 2013

Taking care of your gums by brushing could help hold heart disease at bay

Taking care of your gums by brushing, flossing, and regular dental visits could help hold heart disease at bay. Researchers at Columbia University's Mailman School of Public Health have shown for the first time that as gum health improves, progression of atherosclerosis slows to a clinically significant degree. Findings appear online in the Journal of the American Heart Association.

3 Nov 2013

Study: Dual-pronged strategy could successfully treat childhood cancer

A dual-pronged strategy using two experimental cancer drugs together could successfully treat a childhood cancer by inhibiting tumour growth and blocking off the escape routes it uses to become resistant to treatment, finds a new study.

3 Nov 2013

FDG-PET parameter predicts locally advanced lung cancer survival

High post-treatment concentrations of a radioactive imaging marker are predictive of worse overall survival from inoperable, locally advanced non-small-cell lung cancer, prospective study findings suggest.

31 Oct 2013

DNA methylation signature marks recurrence in early stage lung cancer

An international research team has identified a DNA methylation signature that identifies patients with stage I non-small-cell lung cancer who are at high risk for relapse.

31 Oct 2013

Self-harm warns of repeated suicide attempt risk in schizophrenia

Individuals who have attempted suicide and also have a history of self-harm should be thoroughly assessed for psychotic symptoms in order to prevent delayed treatment and the risk for repeated suicide attempts, say researchers.

31 Oct 2013

Large, rare CNV burden reduced in bipolar disorder

Large and rare chromosomal copy number variants are uncommon in patients with bipolar disorder, even those with early-onset disease, study findings confirm.

31 Oct 2013

Toxicity limits benefits of bevacizumab–erlotinib NSCLC maintenance therapy

Two targeted anticancer drugs used together after first-line chemotherapy for advanced stage non-small-cell lung cancer improve progression-free survival, the results of a large, prospective study show.

31 Oct 2013

New therapeutic approach for treating type 2 diabetes

Scientists from the Helmholtz Zentrum München (HMGU) and the Technische Universität München (TUM), together with scientists in the USA, have developed a new therapeutic approach for treatment of type 2 diabetes.

31 Oct 2013

Researchers identify new way to determine successful surgical outcomes for epilepsy

A discovery from Case Western Reserve and Cleveland Clinic researchers could provide epilepsy patients invaluable advance guidance about their chances to improve symptoms through surgery.

31 Oct 2013

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Making fat cells immortal might seem like a bad idea to most people, but for a team of University of Iowa scientists it was the ideal way to study how the interaction between bacteria and fat cells might contribute to diabetes.

31 Oct 2013

Scientists uncover new mechanism through which gene expression is regulated

A new study by Weill Cornell Medical College scientists reveals a mechanism through which the expression of genes is controlled -- a finding that highlights genetic mutations that can impair the timing of gene expression.

31 Oct 2013

Prestigious Janssen Industry Excellence Awards announced

The prestigious Janssen Industry Excellence Awards were announced as part of the official opening reception for the AusBiotech 2013 Conference at Brisbane City Hall last night; among them, internationally-acclaimed Brisbane-based researcher, Professor Ian Frazer.

31 Oct 2013

Meal replacements and high protein diet can help weight loss maintenance

New research shows that there are several effective strategies available to people wanting to avoid regaining weight after a successful diet. Anti-obesity drugs, meal replacements and a high protein diet can help weight loss maintenance, according to a meta-analysis published in the scientific periodical The American Journal of Clinical Nutrition.

31 Oct 2013

Key differences found in standing posture balance in children with diplegic and hemiplegic cerebral palsy

Improving standing balance in children with cerebral palsy is crucial to improve cognitive and motor functions. Studies have shown differences in sitting balance between children with cerebral palsy and normal children.

31 Oct 2013

Left-handers more likely to suffer from psychotic disorders

Researchers have long studied the connections between hand dominance and different aspects of the human brain. A new study out today in SAGE Open finds that among those with mental illnesses, left-handers are more likely to suffer from psychotic disorders such as schizophrenia than mood disorders.

31 Oct 2013

Rat study shows compulsive gambling behaviours can be reduced in humans

With the help of a rat casino, University of British Columbia brain researchers have successfully reduced behaviours in rats that are commonly associated with compulsive gambling in humans.

31 Oct 2013

Scientists explain genetic and molecular basis of diabetes

In two comprehensive studies, scientists from Helmholtz Zentrum München, Ludwig-Maximilians-Universität München and Technische Universität München discovered new associations of two major type 2 diabetes risk genotypes and altered plasma concentrations of metabolic products.

31 Oct 2013

Scientists identify new toxic entity associated with dementia and motor neuron disease

A new toxic entity associated with genetically inherited forms of dementia and motor neuron disease has been identified by scientists at the UCL Institute of Neurology. The toxin is the result of a genetic mutation that leads to the production of RNA molecules which could be responsible for the diseases. The findings are published in the journal Acta Neuropathologica.

31 Oct 2013

Cellectricon to demonstrate Cellaxess technology at Neuroscience 2013

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will be presenting new data at Neuroscience 2013, 9-13 November, San Diego (USA).

From Cellectricon 31 Oct 2013