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Researchers identify genetic variant in Latina women that protects against breast cancer

An international research collaboration led by UC San Francisco researchers has identified a genetic variant common in Latina women that protects against breast cancer.

20 Oct 2014

Whole exome sequencing can assist in early diagnosis of various disorders

Approximately one-fourth of the 3,386 patients whose DNA was submitted for clinical whole exome testing received a diagnosis related to a known genetic disease, often ending a long search for answers for them and their parents, said researchers from the Baylor College of Medicine departments of molecular and human genetics and pediatrics and the Baylor Human Genome Sequencing Center and the University of Texas Health Science Center at Houston.

20 Oct 2014

Research: Ageing and depression are associated with epigenetic changes

Psychological stress and stress-related psychiatric disorders are associated with increased risk for aging-related diseases, but the molecular mechanisms underlying this relation are unknown.

20 Oct 2014

Animal study shows high-fat diet is more harmful to males than females

Male and female brains are not equal when it comes to the biological response to a high-fat diet.

20 Oct 2014

Genetic changes in blood cells of older people linked to lymphoma, leukemia

At least 2 percent of people over age 40 and 5 percent of people over 70 have mutations linked to leukemia and lymphoma in their blood cells, according to new research at Washington University School of Medicine in St. Louis.

20 Oct 2014

Disruption of circadian rhythm linked to breast cancer, shows study

The disruption of a person's circadian rhythm—their 24-hour biological clock—has been linked to an increased risk of breast cancer, according to new University of Georgia research. The culprit, in this study in particular, is artificial light.

20 Oct 2014

New findings could help develop antibiotics with lower risk of resistance

Scientists have used computer simulations to show how bacteria are able to destroy antibiotics – a breakthrough which will help develop drugs which can effectively tackle infections in the future.

20 Oct 2014

New corneal inlay device offers potential treatment option for presbyopia

A thin ring inserted into the eye could soon offer a reading glasses-free remedy for presbyopia, the blurriness in near vision experienced by many people over the age of 40, according to a study released today at AAO 2014, the 118th annual meeting of the American Academy of Ophthalmology.

20 Oct 2014

Children infected with enterovirus more likely to have type 1 diabetes

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that children who have been infected with enterovirus are 48% more likely to have developed type 1 diabetes. The study is by Dr Tsai Chung-Li, China Medical University, Taiwan, and colleagues.

20 Oct 2014

Low vitamin D levels linked to poor brain function after sudden cardiac arrest

Vitamin D deficiency increases the risk of poor brain function after sudden cardiac arrest by seven-fold, according to research presented at Acute Cardiovascular Care 2014 by Dr Jin Wi from Korea. Vitamin D deficiency also led to a higher chance of dying after sudden cardiac arrest.

20 Oct 2014

New research shows link between birth season and mood disorders

New research shows that the season you are born has a significant impact on your risk of developing mood disorders. People born at certain times of year may have a greater chance of developing certain types of affective temperaments, which in turn can lead to mood disorders (affective disorders).

20 Oct 2014

Depression, anxiety after MI more common in women than men

Women are more likely to develop anxiety and depression after a heart attack (myocardial infarction; MI) than men, according to research presented at Acute Cardiovascular Care 2014 by Professor Pranas Serpytis from Lithuania.

20 Oct 2014

People with severe mental illness use YouTube to provide, receive peer support

People with severe mental illness such as schizophrenia, schizoaffective disorder or bipolar disorder use a popular social media website like YouTube to provide and receive naturally occurring peer support, Dartmouth researchers report in the journal PLOS ONE.

20 Oct 2014

MMP-3 disrupts brain/spinal cord barrier, promotes hemorrhage

Traumatic spinal cord injury (SCI) is a devastating condition with few treatment options. Studies show that damage to the barrier separating blood from the spinal cord can contribute to the neurologic deficits that arise secondary to the initial trauma. Through a series of sophisticated experiments, researchers reporting in The American Journal of Pathology suggest that matrix metalloproteinase-3 (MMP-3) plays a pivotal role in disruption of the brain/spinal cord barrier (BSCB), cell death, and functional deficits after SCI.

20 Oct 2014

Esophageal tissue can be grown in vivo from human and mouse cells, say researchers

In a first step toward future human therapies, researchers at The Saban Research Institute of Children's Hospital Los Angeles have shown that esophageal tissue can be grown in vivo from both human and mouse cells. The study has been published online in the journal Tissue Engineering, Part A.

20 Oct 2014

Study outlines how unique pathogen uses the release of ROS as signal to infect healthy people

New research into a rare pathogen has shown how a unique evolutionary trait allows it to infect even the healthiest of hosts through a smart solution to the body's immune response against it.

20 Oct 2014

Research findings could provide new insights into esophageal cancer, Barrett's esophagus

Despite previous indications to the contrary, the esophagus does have its own pool of stem cells, said researchers from the University of Pittsburgh School of Medicine in an animal study published online today in Cell Reports.

20 Oct 2014

Anaesthesia editorial challenges placenta's role in pre-eclampsia

Pre-eclampsia, the potentially deadly condition that affects pregnant women, may be caused by problems meeting the oxygen demands of the growing fetus, according to an editorial in the November issue of Anaesthesia, the journal of the Association of Anaesthetists of Great Britain and Ireland.

20 Oct 2014

Cannabis use during adolescence: an interview with Dr Edmund Silins

We know quite a lot about the effects of cannabis on the body and brain but there is still a need to better understand its impact on the health, well-being and development of long term users.

20 Oct 2014

Clinical study of Proxima miniature in-line blood gas analyser meets primary end point

Sphere Medical, innovator in critical care monitoring and diagnostics equipment, is pleased to announce the completion of a successful clinical study of its new Proxima miniature in-line blood gas analyser at the Queen Elizabeth Hospital, Birmingham, UK.

17 Oct 2014