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Scientists report new family of selective molecules to combat causal agent of malaria

Malaria is one of the most serious health problems worldwide, registering 200 million clinical cases and more than 600,000 attributable deaths per year, according to information from the World Health Organization in 2013. Given the emerging resistance to the standard treatment most widely used throughout the world, which is based on artemisinin and its analogs, there is a need for new antimalarial compounds.

11 Dec 2014

Researchers pinpoint rare gene mutations that increase risk of heart attack early in life

A team of investigators from the Broad Institute, Massachusetts General Hospital and other leading biomedical research institutions has pinpointed rare mutations in a gene called APOA5 that increase a person's risk of having a heart attack early in life. These mutations disable the APOA5 gene and also raise the levels in the blood of triglyceride-rich lipoproteins, a type of fat.

11 Dec 2014

UT Southwestern microbiologists identify key gut bacteria that promotes foodborne infections

UT Southwestern Medical Center microbiologists have identified key bacteria in the gut whose resources are hijacked to spread harmful foodborne E. coli infections and other intestinal illnesses.

11 Dec 2014

Research finding could lead to development of effective vaccines against microbial infections

The diverse functions of a special cell-recognition lipoprotein, LOX-1, weren't always fully understood. However, Baylor Research Institute investigators gained better insight into LOX-1's role in immune responses through a study recently published in Immunity. Investigators found that the lipoprotein promotes humoral responses, which could allow researchers to design effective vaccines against microbial infections, including influenza viruses and HIV.

11 Dec 2014

New study finds that poor sleep may lead to dementia

People who have sleep apnea or spend less time in deep sleep may be more likely to have changes in the brain that are associated with dementia, according to a new study published in the December 10, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

11 Dec 2014

New therapeutic approach for women with estrogen-receptor-positive breast cancer

Loyola researchers and collaborators have reported promising results from a novel therapeutic approach for women with estrogen-receptor-positive breast cancer.

11 Dec 2014

Researchers identify way to assess women at increased risk for UTI after pelvic-floor surgery

Researchers at Loyola University Chicago Stritch School of Medicine may have identified a way to assess who is at risk for developing a urinary tract infection (UTI) following pelvic-floor surgery.

11 Dec 2014

Sleep-related breathing problems, lack of sleep may increase risk of childhood obesity

Sleep-related breathing problems and chronic lack of sleep may each double the risk of a child becoming obese by age 15, according to new research from Albert Einstein College of Medicine of Yeshiva University. The good news is that both sleep problems can be corrected.

11 Dec 2014

Scientists to explore effectiveness of tadalafil drug to tackle vascular dementia

Scientists are to explore whether drugs usually used to treat erectile problems by expanding blood vessels could become the next major way to tackle the dementia epidemic.

11 Dec 2014

New study investigates Ebola protein

A new study by Robert Stahelin, an adjunct associate professor of chemistry and biochemistry at the University of Notre Dame and an associate professor at the Indiana University School of Medicine-South Bend, as well as a member of Notre Dame's Eck Institute for Global Health, investigates how the most abundant protein that composes the Ebola virus, VP 40, mediates replication of a new viral particle.

11 Dec 2014

New technique allows rapid, large-scale studies of gene function

Using a gene-editing system originally developed to delete specific genes, MIT researchers have now shown that they can reliably turn on any gene of their choosing in living cells.

11 Dec 2014

Stem cells from healthy eye could one day be used to repair scarred cornea

Treating the potentially blinding haze of a scar on the cornea might be as straightforward as growing stem cells from a tiny biopsy of the patient's undamaged eye and then placing them on the injury site, according to mouse model experiments conducted by researchers at the University of Pittsburgh School of Medicine.

11 Dec 2014

$Children who sustain open bone fractures can heal safely without surgery$

Children who sustain open bone fractures can heal safely without surgery

Many children who sustain so-called open bone fractures in the forearm or lower leg can, and do, heal safely without surgery, according to the results of a small study led by investigators at the Johns Hopkins Children's Center.

11 Dec 2014

CUMC researchers devise way to replace torn knee meniscus

Columbia University Medical Center researchers have devised a way to replace the knee's protective lining, called the meniscus, using a personalized 3D-printed implant, or scaffold, infused with human growth factors that prompt the body to regenerate the lining on its own.

11 Dec 2014

Inadequate weight gain during pregnancy puts male fetuses at risk

The amount of weight a woman gains during pregnancy can be vitally important--especially if she's carrying a boy--according to a study by researchers at the University of Georgia released today in PLOS ONE, an open access peer-reviewed journal published by the Public Library of Science.

11 Dec 2014

New research could revolutionise global diagnostic procedures for epilepsy

Pioneering new research by the University of Exeter could revolutionise global diagnostic procedures for one of the most common forms of epilepsy.

11 Dec 2014

NYSCF, CMTA partner to advance research on genetic neuropathies

The New York Stem Cell Foundation Research Institute, a non-profit organization dedicated to accelerating cures through stem cell research, announced a collaboration today with the Charcot-Marie-Tooth Association, a patient-led disease foundation with the mission to advance research on genetic neuropathies that leads to the development of new therapies.

11 Dec 2014

STSI researchers launch study to examine root cause of sudden unexpected death

Researchers at the Scripps Translational Science Institute have launched a clinical trial aimed at cracking one of the toughest mysteries in forensic science -- sudden unexplained death.

11 Dec 2014

Potential new active substances for treating dengue virus

Researchers from Johannes Gutenberg University Mainz and the Julius Maximilian University of Würzburg are proposing potential new active substances for treating the dengue virus. Just like Ebola, dengue fever is also caused by a virus for which there is currently no cure and no vaccine and can be fatal.

11 Dec 2014

Added benefit of daclatasvir drug not proven for chronic hepatitis C infection

The drug daclatasvir (trade name Daklinza) has been available since August 2014 for the treatment of adults with chronic hepatitis C (CHC) infection. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this new drug offers an added benefit over the appropriate comparator therapy.

11 Dec 2014

Medical Research News

Scientists report new family of selective molecules to combat causal agent of malaria

Researchers pinpoint rare gene mutations that increase risk of heart attack early in life

UT Southwestern microbiologists identify key gut bacteria that promotes foodborne infections

Research finding could lead to development of effective vaccines against microbial infections

New study finds that poor sleep may lead to dementia

New therapeutic approach for women with estrogen-receptor-positive breast cancer

Researchers identify way to assess women at increased risk for UTI after pelvic-floor surgery

Sleep-related breathing problems, lack of sleep may increase risk of childhood obesity

Scientists to explore effectiveness of tadalafil drug to tackle vascular dementia

New study investigates Ebola protein

New technique allows rapid, large-scale studies of gene function

Stem cells from healthy eye could one day be used to repair scarred cornea

Children who sustain open bone fractures can heal safely without surgery

CUMC researchers devise way to replace torn knee meniscus

Inadequate weight gain during pregnancy puts male fetuses at risk

New research could revolutionise global diagnostic procedures for epilepsy

NYSCF, CMTA partner to advance research on genetic neuropathies

STSI researchers launch study to examine root cause of sudden unexpected death

Potential new active substances for treating dengue virus

Added benefit of daclatasvir drug not proven for chronic hepatitis C infection

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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