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Metal-free chemical reaction for anti-HIV, anti-cancer and anti-bacterial drugs

A team of researchers from KU Leuven, in Belgium, has developed an economical, reliable and heavy metal-free chemical reaction that yields fully functional 1,2,3-triazoles. Triazoles are chemical compounds that can be used as building blocks for more complex chemical compounds, including pharmaceutical drugs.

4 Jul 2014

Discovery points the way to potential new strategies to treat blood disorders

Like a line of falling dominos, a cascade of molecular events in the bone marrow produces high levels of inflammation that disrupt normal blood formation and lead to potentially deadly disorders including leukemia, an Indiana University-led research team has reported.

4 Jul 2014

Acute kidney injury and chronic kidney disease are interconnected, say GW researchers

For more than 40 years, physicians have treated diminished kidney function as two distinct syndromes: acute kidney injury (AKI) and chronic kidney disease (CKD). However, recent epidemiologic and mechanistic studies suggest the two syndromes are not distinct entities, but interconnected.

4 Jul 2014

TxCell announces launch of POSITIVE project to automate manufacturing process for Ovasave

TxCell SA, a biotech developing innovative, personalized cell-based immunotherapies using antigen-specific regulatory T-cells (Ag-Tregs) for chronic inflammatory and autoimmune diseases, announces today the launch of, and funding awarded to, the POSITIVE project in collaboration with the Gene and Cell therapy Unit (UTCG) developing new antiviral cell-based immunotherapies and Biosafe, a Swiss private company, a developer of innovative solutions for cell processing.

4 Jul 2014

Two life-threatening adverse drug reactions that affect the skin likely to recur

Individuals who are hospitalized for the skin conditions of Stevens-Johnson syndrome and toxic epidermal necrolysis appear to have a high risk of recurrence, according to a study in the June 4 issue of JAMA.

4 Jul 2014

Researchers confirm anecdotal information on patients with Alzheimer's disease, CVD

Researchers from the Sanders-Brown Center on Aging at the University of Kentucky have been able to confirm anecdotal information on patients with both Alzheimer's disease (AD) and cerebrovascular disease (CVD) using mouse models in two different studies.

4 Jul 2014

Researchers reveal how schizophrenia-linked genetic variation alters skeletons of developing brain cells

Johns Hopkins researchers have begun to connect the dots between a schizophrenia-linked genetic variation and its effect on the developing brain. As they report July 3 in the journal Cell Stem Cell, their experiments show that the loss of a particular gene alters the skeletons of developing brain cells, which in turn disrupts the orderly layers those cells would normally form.

4 Jul 2014

Promising new drug for metabolic syndrome

University of Utah researchers have discovered that an enzyme involved in intracellular signaling plays a crucial role in developing metabolic syndrome, a finding that has a U of U spinoff company developing a drug to potentially treat the condition.

4 Jul 2014

Researchers discover new way by which metabolism is linked to regulation of DNA

A research team at the Faculty of Medicine & Dentistry at the University of Alberta have discovered a new way by which metabolism is linked to the regulation of DNA, the basis of our genetic code. The findings may have important implications for the understanding of many common diseases, including cancer.

4 Jul 2014

Researchers unlock secret behind the activation of Ras proteins

A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy.

4 Jul 2014

Leading hypothesis for miscarriages, birth defects ruled out by WSU reproductive biologists

Washington State University reproductive biologists have ruled out one of the leading thoughts on why older women have an increased risk of miscarriages and children with birth defects.

4 Jul 2014

Loss of p62 protein in cells and tissue surrounding a tumor can influence tumor growth

A team of scientists from Sanford Burnham Medical Research Institute has found that the loss of a protein called p62 in the cells and tissue surrounding a tumor can enhance the growth and progression of tumors.

4 Jul 2014

Scientists produce drug compound with potential to block HIV transmission in women

Scientists at the University of Nebraska-Lincoln College of Engineering's Biological Process Development Facility have successfully produced a drug compound with potential to block HIV transmission in women.

4 Jul 2014

New study to explore reasons why women freeze their eggs

A new study will explore the reasons why women freeze their eggs for non-medical reasons.

4 Jul 2014

Study identifies specific coping behaviors through which stress exposure leads to insomnia

A new study is the first to identify specific coping behaviors through which stress exposure leads to the development of insomnia.

4 Jul 2014

Computer simulations show how two knots on DNA strand can interchange positions

Physicists of Johannes Gutenberg University Mainz and the Graduate School of Excellence "Materials Science in Mainz" (MAINZ) have been able with the aid of computer simulations to confirm and explain a mechanism by which two knots on a DNA strand can interchange their positions.

4 Jul 2014

Social environment may influence mood stabiliser adherence

The attitudes of patients with bipolar disorder towards mood-stabilising medications are influenced by their social support system, say researchers.

3 Jul 2014

Thyroxine may overcome mutated thyroid hormone receptor effects

Patients with a mutation in the thyroid hormone receptor α gene that affects both the thyroid hormone receptor α1 and α2 protein variants have similar characteristics to patients with mutations affecting only the α1 variant, report researchers.

3 Jul 2014

Protein may predict outcome of targeted mccRCC therapy

Levels of carbonic anhydrase 9 increase with the use of vascular endothelial growth factor-targeted therapy for metastatic clear-cell renal cancer, and high expression of this protein is associated with increased survival, show study results reported in European Urology.

3 Jul 2014

Factors linked to bipolar cycle acceleration identified

Researchers have identified factors that are associated with cycle acceleration in patients with bipolar disorder admitted to hospital for a mood episode.

3 Jul 2014

Medical Research News

Metal-free chemical reaction for anti-HIV, anti-cancer and anti-bacterial drugs

Discovery points the way to potential new strategies to treat blood disorders

Acute kidney injury and chronic kidney disease are interconnected, say GW researchers

TxCell announces launch of POSITIVE project to automate manufacturing process for Ovasave

Two life-threatening adverse drug reactions that affect the skin likely to recur

Researchers confirm anecdotal information on patients with Alzheimer's disease, CVD

Researchers reveal how schizophrenia-linked genetic variation alters skeletons of developing brain cells

Promising new drug for metabolic syndrome

Researchers discover new way by which metabolism is linked to regulation of DNA

Researchers unlock secret behind the activation of Ras proteins

Leading hypothesis for miscarriages, birth defects ruled out by WSU reproductive biologists

Loss of p62 protein in cells and tissue surrounding a tumor can influence tumor growth

Scientists produce drug compound with potential to block HIV transmission in women

New study to explore reasons why women freeze their eggs

Study identifies specific coping behaviors through which stress exposure leads to insomnia

Computer simulations show how two knots on DNA strand can interchange positions

Social environment may influence mood stabiliser adherence

Thyroxine may overcome mutated thyroid hormone receptor effects

Protein may predict outcome of targeted mccRCC therapy

Factors linked to bipolar cycle acceleration identified

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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