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Researchers identify 10 genes that may signify trifecta of benefits for women with ovarian cancer

Researchers in the Women's Cancer Program at Cedars-Sinai's Samuel Oschin Comprehensive Cancer Institute have identified a series of 10 genes that may signify a trifecta of benefits for women diagnosed with ovarian cancer and ultimately reflect improved survival outcomes.

10 Dec 2013

Scientists devise method to measure forces in 3D tissues, living embryos

As embryonic tissue develops, cells push and pull on each other, and they must do so correctly for the tissue to develop properly. Now scientists at Harvard University have devised the first method to measure these forces in three-dimensional (3D) tissues and living embryos.

10 Dec 2013

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue. The findings are the latest from the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and appear in the December 9 edition of the scientific journal Cancer Cell.

10 Dec 2013

Alnylam presents new pre-clinical data with ALN-AT3 for treatment of hemophilia and RBD

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented new pre-clinical data with ALN-AT3, a subcutaneously administered RNAi therapeutic targeting antithrombin (AT) for the treatment of hemophilia and rare bleeding disorders (RBD), at the 55th Annual Meeting of the American Society of Hematology (ASH) held December 7 - 10, 2013 in New Orleans.

10 Dec 2013

Children hospitalized for pneumonia have similar outcomes with big gun antibiotics or penicillin

Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with "big gun" antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin, according to a Vanderbilt study published in Pediatrics.

10 Dec 2013

Study reveals that germ-free mice are susceptible to infection with foodborne pathogen

When it comes to fighting off pathogens like Listeria, your best allies may be the billions of microorganisms that line your gut, according to new research published in mBio-, the online open-access journal of the American Society for Microbiology.

10 Dec 2013

Scientists discover novel chemical lurking in atmosphere that appears to be LLGHG

Scientists from U of T's Department of Chemistry have discovered a novel chemical lurking in the atmosphere that appears to be a long-lived greenhouse gas (LLGHG). The chemical - perfluorotributylamine (PFTBA) - is the most radiatively efficient chemical found to date, breaking all other chemical records for its potential to impact climate.

10 Dec 2013

Research: Individual alcohol policies can reduce risky drinking

According to a new study, a novel composite measure consisting of 29 alcohol policies demonstrates that a strong alcohol policy environment is a protective factor against binge drinking in the U.S.

10 Dec 2013

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

In nearly one-third of patients with Waldenstrom's Macroglobulinemia, a specific genetic mutation switches on the disease, and a new drug that blocks the defective gene can arrest the disease in animal models, researchers at Dana-Farber Cancer Institute and allied institutions will report at the 2013 annual meeting of the American Society of Hematology.

10 Dec 2013

Private contractors who worked in conflict environments struggle from depression, PTSD

Private contractors who worked in Iraq, Afghanistan or other conflict environments over the past two years report suffering from post-traumatic stress disorder and depression more often than military personnel who served in recent conflicts, according to a new RAND Corporation study.

10 Dec 2013

Orthogonal design to sift optimal parameter of Neiguan acupuncture

The individual difference and non-repeatability in acupuncture have not only restricted the development of acupuncture, but have also affected the specificity of acupoints.

10 Dec 2013

Study recommends cutting down on sweet additive to reduce tooth decay

A study by Newcastle University researchers into the effects of sugars on our oral health recommends cutting down on the sweet additive as part of a global initiative to reduce tooth decay.

10 Dec 2013

Scientists discover how lymphotoxin controls production of immunoglobulins in gut

Lymphotoxin is a cytokine, or intercellular messenger, and plays an important role in the immunological balance of the gastrointestinal tract. It regulates the immune system of the digestive tract, which is made up of immune cells, immunoglobulins (antibodies) as well as intestinal bacteria.

10 Dec 2013

New demographic data unveils extraordinary diversity of aging processes

Despite aging being one the hottest topic in the media recently, scientists have no coherent explanation for it. New demographic data on humans, animals and plants for the first time unveil such an extraordinary diversity of aging processes that no existing evolutionary theory can account for. Both life spans and mortalities vary from species to species.

10 Dec 2013

Study demonstrates feasibility to detect generalized tonic-clonic seizures with arm device

Medications remain the mainstay of epilepsy treatment, and to date there are no FDA-approved devices that provide an accurate means of detection for generalized tonic-clonic seizures, or convulsions, during activities of daily living. Two new studies presented at the American Epilepsy Society's 67th Annual Meeting in Washington D.C. provide data that warrants the development of non-invasive devices with the capability to signal the onset of an epileptic seizure and could be crucial to optimal patient dosing.

10 Dec 2013

Concussive brain injuries can lead to depressive behaviors later in life

A head injury can lead immune-system brain cells to go on "high alert" and overreact to later immune challenges by becoming excessively inflammatory - a condition linked with depressive complications, a new animal study suggests.

10 Dec 2013

Exercise program improves symptoms of depression in patients with Parkinson's disease

A new study by a movement disorder neurologist at The Ohio State University Wexner Medical Center found that depression improved among patients with Parkinson's disease who participated in a long-term group exercise program.

10 Dec 2013

UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

Like tiny construction workers, cells sculpt embryonic tissues and organs in 3D space. This task is complicated and requires constant communication between cells to coordinate their actions and generate the forces that will shape their environment into complex tissue morphologies.

10 Dec 2013

IBN and IBM discover new medical application for converted PET bottles

Researchers at Singapore's Institute of Bioengineering and Nanotechnology (IBN) and California's IBM Research - Almaden (IBM) have discovered a new, potentially life-saving application for polyethylene terephthalate (PET), which is widely used to make plastic bottles.

10 Dec 2013

Athletes playing at higher altitudes suffer fewer concussions

A new study shows that high school athletes playing at higher altitudes suffer fewer concussions than those closer to sea-level, a phenomenon attributed to physiological changes in the brain causing it to fit more tightly in the skull.

9 Dec 2013

Medical Research News

Researchers identify 10 genes that may signify trifecta of benefits for women with ovarian cancer

Scientists devise method to measure forces in 3D tissues, living embryos

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Alnylam presents new pre-clinical data with ALN-AT3 for treatment of hemophilia and RBD

Children hospitalized for pneumonia have similar outcomes with big gun antibiotics or penicillin

Study reveals that germ-free mice are susceptible to infection with foodborne pathogen

Scientists discover novel chemical lurking in atmosphere that appears to be LLGHG

Research: Individual alcohol policies can reduce risky drinking

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

Private contractors who worked in conflict environments struggle from depression, PTSD

Orthogonal design to sift optimal parameter of Neiguan acupuncture

Study recommends cutting down on sweet additive to reduce tooth decay

Scientists discover how lymphotoxin controls production of immunoglobulins in gut

New demographic data unveils extraordinary diversity of aging processes

Study demonstrates feasibility to detect generalized tonic-clonic seizures with arm device

Concussive brain injuries can lead to depressive behaviors later in life

Exercise program improves symptoms of depression in patients with Parkinson's disease

UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

IBN and IBM discover new medical application for converted PET bottles

Athletes playing at higher altitudes suffer fewer concussions

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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