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Ciclosporin no more effective than infliximab in severe UC

Ciclosporin and infliximab have similar efficacy for the treatment of patients with refractory severe ulcerative colitis, show the findings of a multinational trial.

18 Oct 2012

Global anti-tuberculosis campaign now ‘at a crossroads’

Tuberculosis care and control has improved dramatically over the last two decades, but numbers of cases and deaths are still high and multidrug resistant-TB is an under-reported and ever-increasing problem, suggest findings from the World Health Organization Global TB Report 2012.

18 Oct 2012

Blood pressure management may slow cognitive decline in PD

Cognitive dysfunction in Parkinson's disease is linked to neurocirculatory abnormalities such as orthostatic and supine hypertension, suggesting early treatment of such abnormalities may slow cognitive decline, say researchers.

17 Oct 2012

Factors associated with medication non-adherence identified for PD

Depression and complex drug regimens are among the factors associated with non-adherence to medication in patients with Parkinson’s disease, show the findings of a systematic review.

17 Oct 2012

Value of cranberries for UTI prevention called into question

Results from an updated systematic review suggest that the value of cranberry juice or capsule consumption for prevention of urinary tract infections is likely to be limited.

17 Oct 2012

Nonmotor symptoms common in early-stage PD

Nonmotor symptoms occur in nearly all individuals with Parkinson’s disease, Italian study results suggest.

17 Oct 2012

Maternal depression influences infant speech development

The early development of speech perception in infants is affected by both maternal depression and prenatal exposure to serotonin reuptake inhibitors, such that major milestones are either accelerated or delayed, say US and Canadian scientists.

17 Oct 2012

Soccer scores hat-trick for hypertensive men

Soccer training can significantly reduce blood pressure and improve aerobic fitness in hypertensive middle-aged men, researchers say.

17 Oct 2012

Quinic acid derivative shows promise for treating radiation exposure

A quinic acid derivative, known as KZ-41, increases 30-day survival threefold compared with placebo when given to rats 24 hours after exposure to high levels of radiation.

17 Oct 2012

Cytokine levels altered in FEP, schizophrenia patients

Levels of certain cytokines are altered in patients with first-episode psychosis and patients with schizophrenia, research shows.

17 Oct 2012

Nonpsychiatric medical costs high in bipolar disorder patients

The use of nonpsychiatric healthcare services is greater and associated costs higher in bipolar disorder patients than in those without the mood disorder, results from a Taiwanese study show.

17 Oct 2012

Tool reveals myeloproliferative neoplasm patient burden

Researchers have devised a tool to accurately assess the extent of symptoms in patients with myeloproliferative neoplasms.

17 Oct 2012

Genetic signatures for aggressive prostate cancer identified

Researchers have identified two genetic signatures for castration-resistant prostate cancer that may predict the severity of the disease.

17 Oct 2012

HIV infection has been major driver of anal cancer burden

Rising rates of anal cancer among men in the USA have been heavily influenced by the HIV epidemic since the 1980s, a study shows.

17 Oct 2012

Botulinum treatment benefits in BPH maybe down to placebo effect

Treatment with botulinum toxin has proved no more effective than placebo at reducing symptoms in men with lower urinary tract symptoms due to benign prostate hyperplasia, show study findings.

17 Oct 2012

Vision care providers worry about effect of reporting driving concerns

Two-thirds of vision care providers routinely enquire about their older patients’ driving, while almost half believe that reporting patients negatively to government agencies affects the physician–patient relationship, show US study results.

17 Oct 2012

Quitting smoking may improve HRQoL in advanced lung cancer

The health-related quality of life of patients with advanced-stage lung cancer is worsened if they smoke, report UK researchers.

17 Oct 2012

Asian and Pacific Islander diabetes data need segregating

Surveillance statistics that aggregate Asians and Pacific Islanders are misleading in terms of establishing who would benefit most from increased diabetes prevention interventions, report US researchers.

17 Oct 2012

Maintain dogs’ presurgery warmth to avoid hypothermia

Hypothermia is common in dogs after undergoing surgery under anesthetic, especially for diagnostic procedures and when the animal is in poor condition, research indicates.

17 Oct 2012

Dopaminergic treatment has ‘minor impact’ on autonomic symptoms in Parkinson’s

Norwegian researchers say that dopaminergic treatment should be considered for patients with early Parkinson’s disease after finding that dopaminergic medication only has a minor impact on autonomic symptoms after 1 year.

17 Oct 2012