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Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Case Western Reserve University researchers have discovered a novel population of neutrophils, which are the body's infection control workhorses. These cells have an enhanced microbial killing ability and are thereby better able to control infection.

25 Mar 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

tPA can improve chances of recovering from stroke

When the clock starts ticking after the onset of stroke symptoms, access to a neurologist is crucial. Quickly diagnosing a stroke allows for the administration of lifesaving tPA (tissue plasminogen activator) in patients who quality for this treatment.

25 Mar 2014

Women with BRCA1 mutations may have increased risk for rare types of aggressive uterine cancer

Women with BRCA1 mutations may have an increased risk for developing rare types of aggressive uterine cancer despite having their ovaries and fallopian tubes removed, suggest preliminary findings being presented at the Society of Gynecologic Oncology (SGO) Annual Meeting on Women's Cancer in Tampa, Fla., March 22-25.

25 Mar 2014

Study shows how transcription factor p73 promotes process of producing fertile sperm

The process of producing high-quality, fertile sperm requires many steps. A study in The Journal of Cell Biology shows how the transcription factor p73 promotes this process by regulating the adhesions between developing sperm and their support cells.

25 Mar 2014

Research findings underscore importance of mice as reservoirs for tick-borne pathogens

People living in northern and central parts of the U.S. are more likely to contract Lyme disease and other tick-borne ailments when white-footed mice are abundant. Mice are effective at transferring disease-causing pathogens to feeding ticks. And, according to an in-press paper in the journal Ecology, these "super hosts" appear indifferent to larval tick infestations.

25 Mar 2014

XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

Scientists from Weill Cornell Medical College and Houston Methodist have found that a gene previously unassociated with breast cancer plays a pivotal role in the growth and progression of the triple negative form of the disease, a particularly deadly strain that often has few treatment options. Their research, published in this week's Nature, suggests that targeting the gene may be a new approach to treating the disease.

25 Mar 2014

New subcellular mechanism identified for fast transmission in basket cells of the brain

In his third major research paper since December 2013, IST Austria Professor Peter Jonas together with his collaborator, postdoc Hua Hu, identifies a new subcellular mechanism for reliable, fast transmission in the so-called basket cells of the brain.

25 Mar 2014

Researchers develop one-step analysis for detecting tumor markers in blood

Benign growth, or cancer? Tumor markers in the blood help determine whether the patient is afflicted with a malign tumor and whether it is excreting markers more vigorously - involving highly specific proteins. An increased concentration in the blood provides one indication of the disease for physicians. However, it has been quite expensive in time and effort to detect the markers thus far. This is because all kinds of molecules and proteins are teeming in the blood. To be able to detect a single specific one, doctors must first separate and purify the blood in several steps, and then isolate the marker they are searching for from the rest of the molecules.

25 Mar 2014

Study suggests that self-administration of influenza vaccine may be feasible with microneedle patch

There are many reasons some people may not get a flu shot, but would they be more likely to do so if there was a simple device that could be mailed directly to them, was easy enough to use by themselves, and provided at least the same level of protection as a traditional flu shot without the pain of a needle jab? A recent NIBIB-funded study, published online February 2014 in the journal Vaccine, suggests the answer is yes.

25 Mar 2014

$Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture$

Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture

Studies have shown that anyone age 50 or older who suffers a fragility fracture - a bone break sustained in a fall from a standing height or less - is two to five times more likely to experience a second fracture than someone who hasn't had one. The odds that a person who's suffered two such fractures will have a third are even higher.

25 Mar 2014

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

NeuroVive Pharmaceutical AB (publ) and A1M Pharma AB (publ) have announced that the two companies are initiating a research collaboration in mitochondrial medicine. The partnership is governed by a collaboration agreement signed on 21 March 2014.

25 Mar 2014

New technology gives tool to examine membrane proteins in natural environment of human cell

Scientists have a better way to study human proteins - large molecules that are part of every cell in the body - thanks to a new technology developed by University of Toronto researchers.

25 Mar 2014

Low dose injections of artificial properdin provide protection against septic diseases

Researchers at the University of Leicester have produced an artificial version of a naturally occurring protein, properdin, which has been found to successfully combat bacterial pneumonia and meningitis when tested in mice.

25 Mar 2014

Scientists develop new method to deliver cancer-fighting drugs directly to milk ducts

One of every eight women in the United States will develop breast cancer. Though the incidence of breast cancer began decreasing in 2000, it is still the second-leading cause of cancer death in women.

25 Mar 2014

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

A University of Cincinnati (UC) trauma and critical care researcher has received a National Institutes of Health grant to better understand how "microparticles" in stored blood can contribute to inflammation and injury after resuscitation from traumatic injury.

25 Mar 2014

Smokers find difficult to savor bitter taste of caffeine, says study

Smokers and those who have quit cannot fully appreciate the full flavor of a cup of coffee, because many cannot taste the bitterness of their regular caffeine kick. This is the finding of a study led by Nelly Jacob of the Piti--Salp-tri-re Hospital APHP in France, published in Springer's journal Chemosensory Perception.

25 Mar 2014

Medical Research News

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

tPA can improve chances of recovering from stroke

Women with BRCA1 mutations may have increased risk for rare types of aggressive uterine cancer

Study shows how transcription factor p73 promotes process of producing fertile sperm

Research findings underscore importance of mice as reservoirs for tick-borne pathogens

XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

New subcellular mechanism identified for fast transmission in basket cells of the brain

Researchers develop one-step analysis for detecting tumor markers in blood

Study suggests that self-administration of influenza vaccine may be feasible with microneedle patch

Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

New technology gives tool to examine membrane proteins in natural environment of human cell

Low dose injections of artificial properdin provide protection against septic diseases

Scientists develop new method to deliver cancer-fighting drugs directly to milk ducts

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

Smokers find difficult to savor bitter taste of caffeine, says study

Study: Menstrual abnormalities in women with PCOS is strongest predictor for mental health issues

New research reveals new complexity to nerve cells in brain that could affect future therapies

Study uncovers one way that p53 acts to prevent cancer cell invasion

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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