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Two studies shed light on joint replacement outcomes in rheumatoid arthritis patients

Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis. One study overturns the common belief that RA patients have worse outcomes after a total knee replacement than patients who undergo the operation for osteoarthritis. The other study demonstrates that RA patients who undergo a total hip replacement were as likely to have significant improvements in function and pain as patients with osteoarthritis, even though they did not do as well.

12 Jun 2013

Johns Hopkins researchers develop experimental vaccine for TB meningitis

A team of Johns Hopkins researchers working with animals has developed a vaccine that prevents the virulent TB bacterium from invading the brain and causing the highly lethal condition TB meningitis, a disease that disproportionately occurs in TB-infected children and in adults with compromised immune system.

12 Jun 2013

PSMA enzyme could become hallmark of new generation of biomarkers for prostate cancer treatment

No matter where they have hidden, metastatic prostate cancer cells still express some of the same signaling as normal prostate cells; in some cases even more so, as with the PSMA enzyme. Harnessing this enzyme could mean the beginning of a new platform for prostate cancer detection, staging, treatment and post-treatment monitoring, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

12 Jun 2013

Hybrid molecular imaging technique helps doctors identify diabetic foot infection

Researchers are kick-starting better diabetic foot care and promoting reduced radiation dose with a new take on a hybrid molecular imaging technique. By targeting both bone cell activity and immune response and improving imaging data interpretation, doctors can better distinguish diabetic foot infection from another common foot condition that often requires an additional bone-marrow scan for definitive diagnosis, say researchers presenting a study at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

12 Jun 2013

PET and MR imaging can improve quality of life and survival for advanced breast cancer patients

For patients with advanced breast cancer, positron emission tomography and magnetic resonance imaging can improve quality of life and survival by providing physicians with information on the effectiveness of chemotherapy prior to surgery, say researchers presenting at the 2013 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

12 Jun 2013

Countrywide study in Germany deems PRRT as life-prolonging treatment for patients with NETs

Peptide-receptor radionuclide therapy has been a subject of growing research on neuroendocrine tumors, which take up residence in a variety of organs replete with nerve cells that respond to hormone signaling.

12 Jun 2013

Understanding Phelan-McDermid Syndrome

In the first prospective study of its kind, Seaver Autism Center researchers at the Icahn School of Medicine at Mount Sinai provide new evidence of the severity of intellectual, motor, and speech impairments in a subtype of autism called Phelan-McDermid Syndrome.

12 Jun 2013

Research could lead to new ways to combat chlamydia

A protein secreted by the chlamydia bug has a very unusual structure, according to scientists in the School of Medicine at The University of Texas Health Science Center San Antonio. The discovery of the protein's shape could lead to novel strategies for diagnosing and treating chlamydia, a sexually transmitted disease that infects an estimated 2.8 million people in the U.S. each year.

12 Jun 2013

Research discovery could shed light on unsolved cases of arrhythmia

The heart's regular rhythm is crucial to the delivery of oxygenated blood and nutrients to all the organs of the body. It is regulated by a bundle of cells called "the pacemaker," which use electrical signals to set the pace of the heart. Dysfunction in this mechanism can lead to an irregular heartbeat, known as arrhythmia, and often necessitates the implantation of an artificial pacemaker.

12 Jun 2013

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Advanced metastatic melanoma is a disease that has proven difficult to eradicate. Despite the success of melanoma-targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before. In the current issue of the journal Cancer Cell, however, researchers at The Wistar Institute describe how they increase the effectiveness of anti-melanoma drugs by combining anticancer therapies with diabetes drugs.

12 Jun 2013

Research finding offers new insight into stroke rehabilitation

A new study finds that stroke patients' brains show strong cortical motor activity when observing others performing physical tasks - a finding that offers new insight into stroke rehabilitation.

12 Jun 2013

UC Irvine researchers to study how maternal signals and care impact adolescent cognitive behaviors

With $10 million in new federal funding, UC Irvine researchers will study how maternal signals and care before and after birth may increase an infant's vulnerability to adolescent cognitive and emotional problems, such as risky behaviors, addiction and depression.

12 Jun 2013

Nimodipine reduces febrile seizures

Fever-induced childhood seizures, known as febrile seizures, can be terrifying for parents to witness. The full-body convulsions, which mostly affect children six months to five years old, can last from mere seconds up to more than 40 minutes. Currently, children are not treated with daily anticonvulsant medication to prevent these seizures even when they recur repeatedly because toxic side effects of existing treatments outweigh potential benefits.

12 Jun 2013

Growth patterns in 2 months old infants help predict child's weight by age 5

Infants as young as two months old already exhibit growth patterns that can predict the child's weight by age 5, according to researchers at Case Western Reserve University's Frances Payne Bolton School of Nursing and Tennessee State University.

11 Jun 2013

Prostate cancer and DNA: an interview with Dr. Jianfeng Xu, Wake Forest School of Medicine

Prostate cancer development is associated with both inherited and acquired genetic alterations. More than 70 inherited genetic variants have been consistently identified in human DNA that may contribute to susceptibility or risk of prostate cancer.

11 Jun 2013

Study: 35% of designated drivers have high blood-alcohol levels that impair driving

Maybe better call that cab, after all: A new University of Florida study found that 35 percent of designated drivers had quaffed alcohol and most had blood-alcohol levels high enough to impair their driving.

11 Jun 2013

Study shows iron-uptake receptor plays a role in HCV infection

Hepatitis C virus (HCV) infects more than 170 million people worldwide. Approximately 80 percent of infections lead to chronic illness including fibrosis, cirrhosis, cancer and also hepatic iron overload.

11 Jun 2013

U-M, Johns Hopkins researchers receive $1.7M grant to design web-based tool for dementia

Aside from memory loss and cognitive impairments, often the most difficult aspect of caring for people with dementia is treating their disruptive changes in behavior.

11 Jun 2013

Kessler Foundation receives grants from NJ Commission to study deficits in TBI patients

The New Jersey Commission on Brain Injury Research awarded two grants to scientists at Kessler Foundation to study emotional processing deficits in people with traumatic brain injury (TBI) and the effects of aerobic exercise on memory impairments after TBI. The grants exceeded $500,000.

11 Jun 2013

Columbia psychiatry researchers suggest possible approaches to treat or prevent OCD

Columbia Psychiatry researchers have identified what they think may be a mechanism underlying the development of compulsive behaviors. The finding suggests possible approaches to treating or preventing certain characteristics of OCD.

11 Jun 2013

Medical Research News

Two studies shed light on joint replacement outcomes in rheumatoid arthritis patients

Johns Hopkins researchers develop experimental vaccine for TB meningitis

PSMA enzyme could become hallmark of new generation of biomarkers for prostate cancer treatment

Hybrid molecular imaging technique helps doctors identify diabetic foot infection

PET and MR imaging can improve quality of life and survival for advanced breast cancer patients

Countrywide study in Germany deems PRRT as life-prolonging treatment for patients with NETs

Understanding Phelan-McDermid Syndrome

Research could lead to new ways to combat chlamydia

Research discovery could shed light on unsolved cases of arrhythmia

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Research finding offers new insight into stroke rehabilitation

UC Irvine researchers to study how maternal signals and care impact adolescent cognitive behaviors

Nimodipine reduces febrile seizures

Growth patterns in 2 months old infants help predict child's weight by age 5

Prostate cancer and DNA: an interview with Dr. Jianfeng Xu, Wake Forest School of Medicine

Study: 35% of designated drivers have high blood-alcohol levels that impair driving

Study shows iron-uptake receptor plays a role in HCV infection

U-M, Johns Hopkins researchers receive $1.7M grant to design web-based tool for dementia

Kessler Foundation receives grants from NJ Commission to study deficits in TBI patients

Columbia psychiatry researchers suggest possible approaches to treat or prevent OCD

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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