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Scientists discover molecular switch that determines death or survival of cell

The study is the result of a collaboration of scientists at Karolinska Institutet in Sweden, University of Michigan, and University of California San Diego, USA, who were interested in finding out whether autophagy can be affected by events in the cell nucleus. Surprisingly, they discovered that a signal chain in the nucleus serves as a kind of molecular switch that determines whether the cell dies or survives.

19 Jul 2013

Depressive disorder patients exhibit negative bias brain imaging changes and cognitive dysfunction

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19 Jul 2013

Nanotechnology drug kills brain-tumor cells and retards growth of tumor blood vessels

An experimental drug in early development for aggressive brain tumors can cross the blood-brain tumor barrier and kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).

19 Jul 2013

Research shows split liver transplantation carries no increased risk of failure in either recipient

Split liver transplantation carries no increased risk of failure in either recipient, allowing surgeons to safely save two lives from a single donated organ (graft), according to new research from Boston Children's Hospital published online in the Journal of the American College of Surgeons.

19 Jul 2013

Researchers identify genetic cause of severe obesity

Researchers at Boston Children's Hospital have identified a genetic cause of severe obesity that, though rare, raises new questions about weight gain and energy use in the general obese population. The research, published in the journal Science on July 19, involved genetic surveys of several groups of obese humans and experiments in mice.

19 Jul 2013

Three key technologies receive £85 million investment for capital equipment from EPSRC

Three key technologies, identified in the pre-budget statement by The Chancellor of the Exchequer as part of the government's 'eight great technologies' to drive UK growth, are to receive an -85 million investment for capital equipment.

19 Jul 2013

NGM Biopharmaceuticals announces completion of $50 million Series C financing

NGM Biopharmaceuticals, Inc. announced today the successful completion of a $50 million Series C financing to support advancing its portfolio of potential therapeutics for the treatment of diabetes, obesity and other cardio-metabolic diseases.

19 Jul 2013

Researchers develop new drug delivery technique for diabetes treatment

Researchers have developed a drug delivery technique for diabetes treatment in which a sponge-like material surrounds an insulin core. The sponge expands and contracts in response to blood sugar levels to release insulin as needed. The technique could also be used for targeted drug delivery to cancer cells.

19 Jul 2013

Boys more likely to receive HPV4 vaccine if their mothers receive flu shots, study finds

Boys are more likely to receive the quadrivalent human papillomavirus vaccine if their mothers receive flu shots or Pap screenings, according to a Kaiser Permanente study published in the American Journal of Public Health.

19 Jul 2013

Ensemble Therapeutics announces initiation of drug discovery collaboration with Alexion subsidiary

Ensemble Therapeutics, a biotechnology company developing Ensemblins, a novel class of small molecule therapeutics with the potential to modulate targets typically addressed by biologics, today announced the initiation of a drug discovery collaboration with a subsidiary of Alexion Pharmaceuticals, Inc., the global biopharmaceutical company focused on developing and commercializing life-transforming therapies for patients with life-threatening, ultra-rare disorders.

18 Jul 2013

Kolltan signs research agreement with CHOP for novel therapeutic approaches for neuroblastoma

Kolltan Pharmaceuticals, Inc., a privately held biopharmaceutical company, today announced a license and research agreement with The Children's Hospital of Philadelphia to commence a collaboration with Yaël Mossé, M.D, an internationally recognized clinician and scientist for her work studying the causes and novel therapeutic approaches for the treatment of children diagnosed with neuroblastoma.

18 Jul 2013

Oncodesign receives AAALAC certification for Dijon-based research center

Oncodesign, a contract research laboratory for the discovery of new anticancer therapies, today announces that its Dijon-based research center has received AAALAC certification.

18 Jul 2013

Plague detection through anti-carbohydrate antibodies could lead to rapid diagnosis

Even today, the lives of humans and animals are claimed by plague. A new antibody-based detection method can be used to reliably and sensitively identify plague in patient serum and other biological samples.

18 Jul 2013

Study brings new hope for patients with metastatic prostate cancer

A study of a new radiotherapeutic drug published this week in the New England Journal of Medicine brings fresh hope for a particular group of cancer patients that otherwise suffer and ultimately die from the disease -- those with prostate cancer that has spread to their bones and has failed to be controlled by hormone deprivation drugs.

18 Jul 2013

Research: Vegetarian athletes can stay competitive with balanced plant-base diets

A balanced plant-based diet provides the same quality of fuel for athletes as a meat-based diet, provided vegetarians seek out other sources of certain nutrients that are more commonly found in animal products, according to a presentation at the 2013 Institute of Food Technologists Annual Meeting & Expo.

18 Jul 2013

Human filariasis research: an interview with Professor Mark Taylor, Liverpool School of Tropical Medicine

Filariasis refers to a group of diseases caused by parasitic worms, which are transmitted by blood feeding insects. Two species infect the lymphatic and blood systems causing lymphatic filariasis, which in some people can lead to gross swelling of the limbs and 'elephantiasis'.

18 Jul 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene.

18 Jul 2013

Scientists develop iKnife that helps surgeons identify cancerous tissues

Scientists have developed an "intelligent knife" that can tell surgeons immediately whether the tissue they are cutting is cancerous or not.

18 Jul 2013

Study shows positive impact of using music as personal coping method for cancer patients

Very few treatments or therapies endured by cancer patients can be described as pleasant, but a study published in Arts & Health shows the positive impact of using music as a personal coping method when faced with the disease.

18 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

Medical Research News

Scientists discover molecular switch that determines death or survival of cell

Depressive disorder patients exhibit negative bias brain imaging changes and cognitive dysfunction

Nanotechnology drug kills brain-tumor cells and retards growth of tumor blood vessels

Research shows split liver transplantation carries no increased risk of failure in either recipient

Researchers identify genetic cause of severe obesity

Three key technologies receive £85 million investment for capital equipment from EPSRC

NGM Biopharmaceuticals announces completion of $50 million Series C financing

Researchers develop new drug delivery technique for diabetes treatment

Boys more likely to receive HPV4 vaccine if their mothers receive flu shots, study finds

Ensemble Therapeutics announces initiation of drug discovery collaboration with Alexion subsidiary

Kolltan signs research agreement with CHOP for novel therapeutic approaches for neuroblastoma

Oncodesign receives AAALAC certification for Dijon-based research center

Plague detection through anti-carbohydrate antibodies could lead to rapid diagnosis

Study brings new hope for patients with metastatic prostate cancer

Research: Vegetarian athletes can stay competitive with balanced plant-base diets

Human filariasis research: an interview with Professor Mark Taylor, Liverpool School of Tropical Medicine

CHOP-led research increases numbers of patients who could be treated with gene therapy

Scientists develop iKnife that helps surgeons identify cancerous tissues

Study shows positive impact of using music as personal coping method for cancer patients

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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