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Enhancing the NMDA glutamate receptor causes antidepressant-like effects

Thirteen years ago, an article in this journal first reported that the anesthetic medication, ketamine, showed evidence of producing rapid antidepressant effects in depressed patients who had not responded to prior treatments. Ketamine works by blocking one of the targets for the neurotransmitter glutamate in the brain, the N-methyl-D-aspartate (NMDA) glutamate receptor.

20 Nov 2013

Advanced cytotoxins help bacteria survive antibiotics treatment

In spite of the fact that the first antibiotics were discovered almost a century ago, infectious diseases such as tuberculosis, encephalitis and meningitis are still serious diseases for humans in the twenty-first century. The World Health Organization (WHO) estimates that there are more than 8 million new cases of tuberculosis per year on a global scale, and that more than 300,000 of these are due to multidrug-resistant strains that are not only difficult to treat, but are also emerging rapidly in regions such as Eastern Europe.

20 Nov 2013

Higher 36°C temperature as effective as 33°C for therapeutic hypothermia treatment

Therapeutic hypothermia - cooling the body and brain down to 33-C - is the method used worldwide to treat cardiac arrest, even though a lower body temperature may raise the risk of side-effects. However, keeping the temperature steady at 36-C is just as effective, a study led by Lund University researchers has found.

20 Nov 2013

Connectivity, size of brain can predict degree of anxiety in young children

Prolonged stress and anxiety during childhood is a risk factor for developing anxiety disorders and depression later in life. Now, Stanford University School of Medicine researchers have shown that by measuring the size and connectivity of a part of the brain associated with processing emotion - the amygdala - they can predict the degree of anxiety a young child is experiencing in daily life.

20 Nov 2013

Special issue on Helicobacter pylori provides new insights into diagnosis, prevention and treatment

A special issue on Helicobacter pylori has been published by Landes Bioscience (Austin, TX USA). The articles contained in this special issue of the journal Gut Microbes have been authored by world-class investigators and provide new insights into the pathophysiology, diagnosis, prevention, and treatment of this microbe.

20 Nov 2013

Mount Sinai researchers win Best Manuscript Award for research on repair, reversal of heart attack damage

The Editors of the American Heart Association's (AHA) journal Circulation Research have awarded Icahn School of Medicine at Mount Sinai researchers a "Best Manuscript Award" for their investigations on repair and reversal of heart attack damage.

20 Nov 2013

Adverse events linked with HPV vaccine appear to be related with media coverage

The number of adverse events associated with the HPV vaccine reported to the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) appeared to be related to media coverage and online controversy about the vaccine, finds a study in the Journal of Adolescent Health.

20 Nov 2013

NIAID awards $4.4M grant to study unknown gene function in bacteria that cause plague, brucellosis

The National Institute of Allergy and Infectious Diseases has awarded the University of Chicago $4.4 million over five years to study genes of unknown function in bacteria that cause plague and brucellosis.

20 Nov 2013

Simple blood test may predict people at highest risk for developing heart problems

For years, doctors have been divided on how effective annual testing and screenings are for apparently healthy individuals. New research, however, shows that a simple blood test may predict who is at highest risk to develop heart problems - and how long these people may have to live.

20 Nov 2013

Findings could potentially save millions of people from having unnecessary cardiac catheterization

An ultrafast, 320-detector computed tomography scanner that shows both anatomy within coronary arteries and blood flow can accurately sort out which people need - or don't need - an invasive procedure to identify coronary blockages, according to an international study. The researchers say their findings could potentially save millions of people worldwide from having an unnecessary cardiac catheterization.

20 Nov 2013

Study finds resveratrol in colored vegetables, fruits may block effects of methamphetamine

Studies have shown that resveratrol, a natural compound found in colored vegetables, fruits and especially grapes, may minimize the impact of Parkinson's disease, stroke and Alzheimer's disease in those who maintain healthy diets or who regularly take resveratrol supplements.

20 Nov 2013

Data from CT scans can be used with 3-D printers to make accurate copies of fossilized bones

Data from computed tomography (CT) scans can be used with three-dimensional (3-D) printers to make accurate copies of fossilized bones, according to new research published online in the journal Radiology.

20 Nov 2013

New paper highlights correlations between changes in natural systems and potential health outcomes

A new paper from members of the HEAL (Health & Ecosystems: Analysis of Linkages) consortium delineates a new branch of environmental health that focuses on the public health risks of human-caused changes to Earth's natural systems.

20 Nov 2013

Study finds patients with focal epilepsy have widespread, abnormal connections in their brains

Patients with the most common form of focal epilepsy have widespread, abnormal connections in their brains that could provide clues toward diagnosis and treatment, according to a new study published online in the journal Radiology.

20 Nov 2013

Findings underscore importance of obesity prevention and nutrition in addressing metabolic syndrome

Data reported by the Hearts Beat Back: The Heart of New Ulm Project reinforce the positive influence of lifestyle factors in mitigating risks that potentially increase the likelihood of heart disease and other health problems. Findings based on 1,059 residents of New Ulm, Minn, underscore the importance of obesity prevention and nutrition, specifically eating more fruits and vegetables, in addressing metabolic syndrome, a common precursor to cardiovascular disease.

20 Nov 2013

Teens who experience deployment of parent in military are more likely to be depressed

It is widely known that deployment is stressful for military families, including their children. A new study in the Journal of Adolescent Health finds that teens from military families are more likely to feel sad or hopeless, have thoughts about suicide and symptoms of depression than teens of civilian families.

20 Nov 2013

Women who attempted VBAC had 63% successful natural delivery

Almost two-thirds of women who attempt a natural delivery after having a caesarean section for their first birth are successful, according to a new study published today (20 November) in BJOG: An International Journal of Obstetrics and Gynaecology.

20 Nov 2013

Research provides first rigorous comparison of 2 surgical approaches for severe heart valve disease

New research presented today at the 2013 Scientific Sessions of the American Heart Association by researchers at the Perelman School of Medicine at the University of Pennsylvaniafound no difference in outcomes at one-year between two recommended surgical options for treating ischemic mitral regurgitation (IMR) - repair of the leaky valve or its replacement with an artificial valve.

20 Nov 2013

New approach may help researchers find new drugs for human diseases

A team of biochemists and mathematicians have developed a sophisticated geometric model to predict how a biological molecule will interact with water molecules, computing the results up to 20 times faster than other existing approaches. This new approach may help researchers find new drugs to treat human diseases, said the team, who described their theoretical approach in the Journal of Chemical Physics, which is produced by AIP Publishing.

20 Nov 2013

Many primary care pediatricians feel uncomfortable in providing care to patients with genetic disorders

Many primary care pediatricians say they feel uncomfortable providing health care to patients with genetic disorders. Also, many do not consistently discuss all risks and benefits of genetic tests with patients, according to research published today in the American Journal of Medical Genetics.

20 Nov 2013

Medical Research News

Enhancing the NMDA glutamate receptor causes antidepressant-like effects

Advanced cytotoxins help bacteria survive antibiotics treatment

Higher 36°C temperature as effective as 33°C for therapeutic hypothermia treatment

Connectivity, size of brain can predict degree of anxiety in young children

Special issue on Helicobacter pylori provides new insights into diagnosis, prevention and treatment

Mount Sinai researchers win Best Manuscript Award for research on repair, reversal of heart attack damage

Adverse events linked with HPV vaccine appear to be related with media coverage

NIAID awards $4.4M grant to study unknown gene function in bacteria that cause plague, brucellosis

Simple blood test may predict people at highest risk for developing heart problems

Findings could potentially save millions of people from having unnecessary cardiac catheterization

Study finds resveratrol in colored vegetables, fruits may block effects of methamphetamine

Data from CT scans can be used with 3-D printers to make accurate copies of fossilized bones

New paper highlights correlations between changes in natural systems and potential health outcomes

Study finds patients with focal epilepsy have widespread, abnormal connections in their brains

Findings underscore importance of obesity prevention and nutrition in addressing metabolic syndrome

Teens who experience deployment of parent in military are more likely to be depressed

Women who attempted VBAC had 63% successful natural delivery

Research provides first rigorous comparison of 2 surgical approaches for severe heart valve disease

New approach may help researchers find new drugs for human diseases

Many primary care pediatricians feel uncomfortable in providing care to patients with genetic disorders

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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