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Florida Hospital, Sanford-Burnham and Takeda renew research agreement

Sanford-Burnham Medical Research Institute (Sanford-Burnham) and Florida Hospital announced today that they have renewed a research agreement with Takeda Pharmaceutical Company Limited (Takeda) to extend their collaboration to discover and evaluate new therapeutic approaches to obesity. The collaboration uses a research and drug-development model that creates an early feedback loop in the discovery pipeline.

12 Feb 2013

New cancer research to be highlighted in AACR Annual Meeting 2013

The AACR Annual Meeting 2013 will bring more than 17,000 scientists, advocates, industry leaders and other professionals to Washington, D.C., for the latest in breakthrough cancer science.

12 Feb 2013

Short but frequent exercise best for beating weight gain

Results from a small exploratory study suggest that short bouts of intermittent exercise may stimulate fat metabolism more effectively than longer continuous exercise sessions.

11 Feb 2013

MRI promising for noninvasive hepatic steatosis assessment

Magnetic resonance imaging allows accurate measurement of the extent and severity of hepatic steatosis in patients with nonalcoholic fatty liver disease, demonstrate the results of two studies published in Radiology.

11 Feb 2013

Modified measure quickly and effectively gauges intraventricular hemorrhage

Researchers have modified the Graeb score to produce a reliable, simple, quick, and clinically meaningful approximation of intraventricular hemorrhage volume.

11 Feb 2013

Biomarkers could be antidote to overdose overtreatment

Researchers have identified several biomarkers that can accurately predict acute liver injury after acetaminophen overdose.

11 Feb 2013

Lipid associated variant linked to aortic stenosis, valve disorders

People who carry a lipoprotein(a) gene variant are at increased risk for aortic valve calcification and aortic stenosis, suggest study findings.

11 Feb 2013

Oral Candida infection weakens tooth enamel

Oral infection with Candida albicans is associated with demineralization of tooth enamel, potentially increasing susceptibility to caries, research shows.

11 Feb 2013

Arrhythmia may confound heart failure treatment

Meta-analysis findings question whether beta-blocker treatment remains effective in patients who have heart failure with reduced left ventricular ejection fraction if they also have atrial fibrillation.

11 Feb 2013

Individualized flu immune responses revealed by high-throughput sequencing

Researchers have shown that it is possible to create personalized, individual-specific measurements of the antibody repertoire in response to influenza vaccination using high-throughput DNA sequencing technology.

11 Feb 2013

Bladder reconstruction rate after cystectomy varies

The use of bladder orthotopic reconstruction after cystectomy for cancer is uncommon in England and varies significantly among patient groups, report researchers.

11 Feb 2013

'Urgent need’ for primary care pneumonia diagnosis tools

While family doctors can exclude pneumonia with a high level of accuracy, they can only identify around a third of radiographically confirmed cases, research shows.

11 Feb 2013

Steroid therapy impedes Duchenne’s cardiomyopathy

Steroid therapy is associated with a considerable reduction in all-cause mortality and new-onset and progressive cardiomyopathy in patients with the debilitating X-linked disease Duchenne muscular dystrophy.

11 Feb 2013

Higher arm reading ‘overestimates true BP’

Using the higher of left and right arm single blood pressure readings taken sequentially leads to an overestimation of patients’ “true” level as determined by ambulatory monitoring, UK researchers warn.

11 Feb 2013

Bronchiolitis, air pollution have ‘synergistic effect’ on asthma risk

Results from a Korean study show that a history of bronchiolitis plus exposure to increased levels of air pollution “synergistically” increases a child’s risk for asthma.

11 Feb 2013

Work stress ‘unlikely’ cause of cancer

Work-related stress is unlikely to be a major cause of cancer, say researchers who found no link between job strain and the risk for overall or site-specific malignancy.

11 Feb 2013

Valproate, pregnancy and IQ: an interview with Professor Kimford Meador

Valproate (sodium salt of valproic acid) is an anticonvulsant used in the treatment of epilepsy, migraine and bipolar disorder as well as some other off label psychiatric indications.

11 Feb 2013

Case Western Reserve receives $220,000 grant to study gastric cancers

The Case Western Reserve University School of Medicine has received a $220,000 grant from the DeGregorio Family Foundation to study gastric cancers, which remain among the most deadly forms of disease.

11 Feb 2013

NIH researchers review research on dog cranium development

Man's best friend may touch our hearts with their empathy, companionship, playfulness and loyalty, and they may also lead us to a deeper understanding of our heads.

11 Feb 2013

Diet high in fruits and vegetables may help protect kidneys of patients with CKD

Adding fruits and vegetables to the diet may help protect the kidneys of patients with chronic kidney disease (CKD) with too much acid build-up, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

10 Feb 2013