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Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure - a leading cause of death worldwide. The team discovered a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.

2 Aug 2013

Omega-3 fatty acids can be used for treatment, prevention of skin and oral cancers: Research

Omega-3 fatty acids, contained in oily fish such as salmon and trout, selectively inhibit growth and induce cell death in early and late-stage oral and skin cancers, according to new research from scientists at Queen Mary, University of London.

2 Aug 2013

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized, or spread, to the patient's brain.

2 Aug 2013

Health care providers are missing opportunities to improve teens' vaccination coverage

Health care providers are missing opportunities to improve teens' vaccination coverage, reports a new study in the Journal of Adolescent Health.

2 Aug 2013

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Bethesda, MD-Japanese researchers have made a new step toward understanding why-and how to stop-runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 issue of The FASEB Journal scientists show that two receptors of an inflammatory molecule, called "leukotriene B4," play opposing roles in turning inflammation on and off for allergic asthma and COPD.

2 Aug 2013

Visual images of skin cancer most effective in prompting skin self-examinations

Seeing pictures of skin cancer motivates people to regularly check their own moles, according to a new research paper from the School of Public Health and Health Systems at the University of Waterloo.

2 Aug 2013

Researchers hope to exploit unique metabolic profile of cancer

Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies.

2 Aug 2013

BMC, BUSM and JIPMER to jointly research on tuberculosis

Boston Medical Center and Boston University School of Medicine are partnering with the Jawaharlal Institute of Postgraduate Medical Education and Research to study tuberculosis. This research is supported by a five-year, $2.5 million grant from the Indo-U.S. Vaccine Action Program.

2 Aug 2013

Deletion of a protein improves ability to fight bacteria in mice with CGD

Deletion of a protein in white blood cells improves their ability to fight the bacteria staphylococcus aureus and possibly other infections in mice with chronic granulomatous disease (CGD), according to a National Institutes of Health study. CGD, a genetic disorder also found in people, is marked by recurrent, life-threatening infections. The study's findings appear online in The Journal of Clinical Investigation.

2 Aug 2013

New type of chemical modification affects proteins, could provide insights into causes of cancer

Scientists at The Scripps Research Institute (TSRI) have discovered a new type of chemical modification that affects numerous proteins within mammalian cells. The modification appears to work as a regulator of important cellular processes including the metabolism of glucose.

2 Aug 2013

Researchers identify new culprit that likely plays big role in severity of asthma

MD-A new culprit has been identified that likely plays a big role in the severity of asthma-a small protein chemokine called CCL26. These findings were published in the Journal of Leukocyte Biology and represent the first demonstration that CCL26 is a potent regulator of the migration of asthmatic eosinophils, commonly observed in asthmatic airways. Results from this discovery may lead to new drug targets for the treatment of asthma.

2 Aug 2013

Neuroscientists identify protein that contributes to cognitive deficits in AS

A team of neuroscientists has identified a protein in laboratory mice linked to impairments similar to those afflicted with Angelman syndrome (AS)—a condition associated with symptoms that include autism, intellectual disability, and motor abnormalities.

2 Aug 2013

Study: Ultrasound treatments may prevent acute kidney injury

Ultrasound treatments may prevent acute kidney injury that commonly arises after major surgery, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that this simple and noninvasive therapy may be an effective precaution for patients at risk.

2 Aug 2013

Study: New therapeutic approach to treat prostate cancer

A study in the Journal of Biological Chemistry identifies a new therapeutic approach to treat prostate cancer. Conducted at Cincinnati Children's Hospital Medical Center, the research shows that expression of the FoxM1 protein is essential for prostate cancer to develop in mouse models. The study appears in the journal's Aug. 2 edition.

2 Aug 2013

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

The most commonly diagnosed form of breast cancer, termed estrogen receptor positive or ER+, accounts for the largest percentage of breast cancer deaths each year. Research by scientists at the HudsonAlpha Institute for Biotechnology and the University of Alabama at Birmingham Comprehensive Cancer Center aims to provide physicians a more targeted approach to treating ER+ breast cancer.

2 Aug 2013

Scientists use fMRI and EEG to unlock one of the human brain's mysteries

Physicists and neuroscientists from The University of Nottingham and University of Birmingham have unlocked one of the mysteries of the human brain, thanks to new research using functional Magnetic Resonance Imaging (fMRI) and electroencephalography (EEG).

2 Aug 2013

Soaring rates of peripheral artery disease call for global attention

The number of people with peripheral artery disease worldwide has risen dramatically (by 23.5%) in just 10 years, from about 164 million in 2000 to 202 million in 2010, according to the first robust global estimates, published in The Lancet.

1 Aug 2013

New report shows that access to clean water and soap may boost growth in children

Improving water quality and hygiene practices may improve the growth of children, according to a new report. The Cochrane review – authored by the London School of Hygiene & Tropical Medicine and WaterAid – found evidence of small but significant improvements in growth of children under the age of five who have access to clean water and soap.

1 Aug 2013

Research findings expand current understanding of postpartum sexuality

Partners of new mothers often experience shifts in sexuality, and these shifts are often unrelated to biological or medical factors pertaining to childbirth. The findings, which are published in a recent issue of The Journal of Sexual Medicine, expand current understanding of postpartum sexuality, and may help health professionals as they counsel new parents.

1 Aug 2013

Study proposes novel approach for understanding how genome affects biology of the human body

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. To apply this knowledge towards prevention or cure, including tailoring treatment to the patient’s genetic profile –also known as personalized medicine – we need to know how this genetic variant affects health.

1 Aug 2013

Medical Research News

Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

Omega-3 fatty acids can be used for treatment, prevention of skin and oral cancers: Research

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Health care providers are missing opportunities to improve teens' vaccination coverage

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Visual images of skin cancer most effective in prompting skin self-examinations

Researchers hope to exploit unique metabolic profile of cancer

BMC, BUSM and JIPMER to jointly research on tuberculosis

Deletion of a protein improves ability to fight bacteria in mice with CGD

New type of chemical modification affects proteins, could provide insights into causes of cancer

Researchers identify new culprit that likely plays big role in severity of asthma

Neuroscientists identify protein that contributes to cognitive deficits in AS

Study: Ultrasound treatments may prevent acute kidney injury

Study: New therapeutic approach to treat prostate cancer

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

Scientists use fMRI and EEG to unlock one of the human brain's mysteries

Soaring rates of peripheral artery disease call for global attention

New report shows that access to clean water and soap may boost growth in children

Research findings expand current understanding of postpartum sexuality

Study proposes novel approach for understanding how genome affects biology of the human body

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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