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Janssen, Orexo to end OX-CLI/OX-ESI research collaboration and license agreement

Orexo AB and Janssen Pharmaceuticals, Inc., formerly Ortho-McNeil-Janssen Pharmaceuticals, Inc. and Janssen Pharmaceutica NV, have decided to end their research collaboration and license agreement regarding the OX-CLI and OX-ESI programs and a third, undisclosed Janssen program.

31 Jan 2012

Tobacco smoking may increase risk of esophageal cancer in Barrett's patients

Barrett's esophagus (BE) patients who smoke tobacco are at a two-fold increased risk of developing esophageal cancer, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. BE patients who smoke also double their risk for developing advanced precancerous cells.

31 Jan 2012

Musical training can avoid age-related hearing loss

Age-related delays in neural timing are not inevitable and can be avoided or offset with musical training, according to a new study from Northwestern University. The study is the first to provide biological evidence that lifelong musical experience has an impact on the aging process.

31 Jan 2012

Tailored approach may help prevent heavy drinking in college students

The first few weeks of college are a critical time in shaping students' drinking habits. Now Penn State researchers have a tailored approach that may help prevent students from becoming heavy drinkers.

31 Jan 2012

Abbott, DNDi partner to research on new treatments for NTDs

The Drugs for Neglected Diseases initiative (DNDi) and Abbott have signed a four-year joint research and non-exclusive licensing agreement to undertake research on new treatments for several of the world's most neglected tropical diseases, including Chagas disease, helminth infections, leishmaniasis and sleeping sickness.

31 Jan 2012

Watson plans to establish Global R&D Technology Center in North Brunswick

Watson Pharmaceuticals, Inc. today announced plans to establish a Global R&D Technology Center in North Brunswick, New Jersey.

30 Jan 2012

KineMed, Pfizer enter research collaboration on metabolic diseases

KineMed, Inc. today announced a non-exclusive research collaboration with Pfizer Inc. for the advancement of novel approaches towards metabolic disease, in particular Type II Diabetes.

30 Jan 2012

Negative outlook need not have to be permanent in chronic melancholics

Good news for the 13 per cent of the population with depressive personality traits: their negative outlook does not have to be permanent. This has been shown by psychologist Rachel Maddux in new research from Lund University in Sweden.

30 Jan 2012

Family participation in school-based interventions can help reduce problem behavior in teens

When parents of middle school students participate in school-based, family interventions, it can reduce problem behavior, according to new research released online in the Journal of Adolescent Health.

30 Jan 2012

Signs motivate more people to take the stairs

Signs that read, "Burn Calories, Not Electricity" posted in lobbies of New York City buildings, motivated more people to take the stairs and continue to use them even months later.

30 Jan 2012

Teens who drive with peers have increased risks of crashing

Research shows that teens who drive with peers as passengers have increased risks of crashing. Many states have responded by creating graduated driver licensing laws which include limits on the number of passengers teen drivers can have.

30 Jan 2012

People underestimate weight and overestimate height during research surveys

When people in the U.S. are asked to provide their weight for research surveys, they underestimate their weight and overestimate their height, despite numerous public reports about increasing rates of obesity. Whites are more likely to do so than Blacks or Hispanics, a new study finds.

30 Jan 2012

Blood sugar self-monitoring has no benefit for diabetics not on insulin

For type 2 diabetics who are not on insulin, monitoring their blood sugar does little to control blood sugar levels over time and may not be worth the effort or expense, according to a new evidence review.

30 Jan 2012

International Roadmap for TB Research outlines priorities

In this post in the PLoS "Speaking of Medicine" blog, guest blogger Christian Lienhardt, senior scientific adviser at the Stop TB Partnership and WHO, "discusses the International Roadmap for Tuberculosis (TB) Research, a framework outlining priority areas for investment in TB research."

30 Jan 2012

IGC researcher awarded ERC Advanced Grant for tissue damage study

There is more to fighting infection than just clearing the body of pathogens. As important as resisting infection, is limiting damage to the host's tissue caused, very frequently, by toxins produced by pathogens or by components of the host immune response that clears those pathogens.

30 Jan 2012

Pleasurability of scratching for itch relief is related to body location

New research from Gil Yosipovitch, M.D., Ph.D., professor of dermatology at Wake Forest Baptist Medical Center and a world-renowned itch expert, shows that how good scratching an itch feels is related to the itch's location.

30 Jan 2012

Hard drug users in 50s more likely to die earlier

Young adults often experiment with hard drugs, such as cocaine, amphetamines and opiates, and all but about 10 percent stop as they assume adult roles and responsibilities. Those still using hard drugs into their 50s are five times more likely to die earlier than those who do not, according to a new study by University of Alabama at Birmingham researchers published online Jan. 27, 2012, in the Journal of General Internal Medicine.

30 Jan 2012

SENP1 prevents STAT5 from becoming trapped in nucleus

When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports today in Molecular Cell.

30 Jan 2012

Researchers study new strategies to treat patients with influenza

Influenza virus can rapidly evolve from one form to another, complicating the effectiveness of vaccines and anti-viral drugs used to treat it. By first understanding the complex host cell pathways that the flu uses for replication, University of Georgia researchers are finding new strategies for therapies and vaccines, according to a study published in the January issue of the Journal of the Federation of American Societies for Experimental Biology.

30 Jan 2012

OHSU research sheds light on molecules involved in cardiorespiratory control

Researchers at Oregon Health & Science University have discovered that a molecule critical to the development and plasticity of nerve cells - brain-derived neurotrophic factor -- is severely lacking in brainstem neurons in mutations leading to Rett syndrome, a neurological developmental disorder.

30 Jan 2012