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Advanced cancer patients able to state their own pain goals

Advanced cancer patients are successfully able to express their desired level of pain relief on a scale of 1–10, indicating that personalized pain goals could be a novel target for pain treatment response, say researchers.

2 Aug 2012

Sickle cell trait link with sudden athlete death ‘confirmed’

Researchers say they have definitively confirmed that there is a link between the sickle cell trait and sudden cardiac death in African–American athletes.

2 Aug 2012

Emergency diverticulitis surgery victim of the ‘weekend effect’

Patients who have emergency surgery at weekends for acute diverticulitis have worse outcomes than those admitted on weekdays, the results of a US study show.

2 Aug 2012

Position paper recommends standards for quality assessment of CPD for medicines R&D

This position paper recommends a set of standards for quality assessment of continuing professional development (CPD) for medicines research and development (R&D).

2 Aug 2012

People with diabetes, hypertension and hyperlipidemia have difficultly managing all 3 conditions

Most people who have diabetes, high blood pressure, and high cholesterol have difficultly managing all three conditions; indeed, success is fleeting for those who do manage all three, according to a Kaiser Permanente Institute for Health Research study that appears online in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.

1 Aug 2012

Heart pumping exercises may reduce risk of dementia and mild cognitive impairment

The physical benefits of the Olympic sports are pretty obvious: strength, endurance and agility, to name a few. But did you know they also can help the brain? Mayo Clinic research shows that any exercise that gets the heart pumping may reduce the risk of dementia and mild cognitive impairment -- and slow those conditions if they start. Aerobic exercise also can boost your mood.

1 Aug 2012

Transfer of radioactive compounds in ecosystems is not straightforward

A new study by Tiina Tuovinen, from the University of Eastern Finland, and her colleagues casts doubt over the validity of models used to assess the impact of radiation on human health. Their work is published online in Springer's journal Hydrobiologia.

1 Aug 2012

Pediatric liver transplant recipients have increased risk of death when from obese donors

Children undergoing liver transplantation are at greater risk of graft loss and death from adult organ donors who are severely obese according to research published in the August issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases. The study, funded in part by a grant from the National Institutes of Health (NIH), found that pediatric donor body mass index (BMI) did not increase mortality risk in this pediatric population.

1 Aug 2012

NICE commissioning targets unveiled

NICE has released the full menu of Commissioning Outcomes Framework indicators that it is proposing CCG performance should be judged on from 2013.

1 Aug 2012

Surgery avoidable for some with persistent incontinence after prostatectomy

Researchers have identified factors that could help determine whether patients who have not recovered urinary continence more than 1 year after undergoing radical prostatectomy should undergo further surgery.

1 Aug 2012

Obesity affects musculoskeletal pain score in adolescents

Obese adolescents are significantly more likely to report musculoskeletal pain than their nonobese counterparts, researchers report.

1 Aug 2012

Low-cost device affords motor deficiency patients gaze-control

Researchers have developed a low-cost, 3D gaze estimation device to complement direct brain–machine interfaces, which could allow patients with serious motor deficiencies to interact with computers and their surroundings.

1 Aug 2012

Shampoo effective for pruritus relief in dogs

Shampooing dogs with pruritus is an effective method to reduce symptoms even if the shampoo does not contain any active ingredients, report researchers in Veterinary Record.

1 Aug 2012

Narrative skills track cognition in children with language impairments

Children with specific language impairment show poor general narrative skills alongside deficits in verbal working memory and sustained auditory attention relative to children with typical development, research shows.

1 Aug 2012

EEA stapler offers hemostasis advantage over PPH

The EEA stapler may have benefits over the PPH stapler for circular stapled hemorrhoidopexy, the results of the first head-to-head study of the devices show.

1 Aug 2012

Brain protein changes in PD with dementia differ from those in AD

Amyloid beta protein accumulation without neocortical tau deposition is a common pathologic feature of Parkinson’s disease with dementia, according to study findings.

1 Aug 2012

Gene discovery made for infant-onset blindness

Researchers have discovered that mutations in the NMNAT1 gene encoding nicotinamide mononucleotide adenylyltransferase 1 are present in patients with Leber congenital amaurosis.

1 Aug 2012

ART resistance increasing in sub-Saharan Africa

The prevalence of antiretroviral drug resistance is on the rise in sub-Saharan Africa, an increase driven by resistance to non-nucleoside reverse transcriptase inhibitors in east and southern Africa, research shows.

1 Aug 2012

Postoperative QT prolongation common

Most patients have QT interval prolongation immediately after undergoing noncardiac surgery, say researchers.

1 Aug 2012

Lipid treatment absolved of hemorrhagic transformation guilt

The lipid profiles of patients undergoing thrombolysis for acute stroke predict their mortality risk but not their risk for symptomatic intracerebral hemorrhage, shows a large study.

1 Aug 2012