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ArQule, Daiichi Sankyo enter license agreement for development of new AKT inhibitor

ArQule, Inc. and Daiichi Sankyo, Co. Ltd. announced today the execution of a license agreement for the development of a new AKT inhibitor called ARQ 092, the first compound to emerge from the companies' November 2008 agreement to collaborate on research utilizing the AKIP (ArQule Kinase Inhibitor Platform) technology to generate novel, selective and potent small molecule kinase inhibitors.

10 Nov 2011

Enzyme research may lead to drugs with fewer side effects

A tree outside Oak Ridge National Laboratory researcher Pratul Agarwal's office window provided the inspiration for a discovery that may ultimately lead to drugs with fewer side effects, less expensive biofuels and more.

10 Nov 2011

IRCM peptide chemist listed as inventor on two U.S. patents

In 2010, after more than 10 years of basic research, Dr. Peter W. Schiller, a world-renowned peptide chemist and Director of the Chemical Biology and Peptide research unit at the Institut de recherches cliniques de Montr-al (IRCM), and his international collaborators were the listed inventors on two U.S. patents awarded to the institute and covering different uses of a unique class of peptide compounds initially synthesized in Dr. Schiller's laboratory at the IRCM.

10 Nov 2011

Maxygen's MAXY-G34 for Acute Radiation Syndrome not considered for BARDA award

Maxygen, Inc. today announced that it has been advised by the Biomedical Advanced Research and Development Authority (BARDA) that Maxygen's proposal for the development of its MAXY-G34 product candidate as a potential medical countermeasure for Acute Radiation Syndrome (ARS) will not be considered for a contract award.

10 Nov 2011

'Social Norms and Alcohol Prevention' to address problem drinking in college students

Perceptions of peer drinking of alcohol may be the strongest predictor of excessive alcohol use among college students according to new research by Clayton Neighbors, a professor and director of the social psychology program in the department of psychology at the University of Houston.

10 Nov 2011

Rensselaer engineer receives $1.4M NIH grant to study new method to heal traumatic nerve damage

Injuries to the nervous system affect large numbers of people globally. Such injuries can result in loss of feeling or movement. With a new $1.4 million grant from the National Institutes of Health, Deanna Thompson, associate professor of biomedical engineering at Rensselaer Polytechnic Institute, will investigate a promising new method to heal traumatic nerve damage, using electrical stimulation to prime and pump neuronal growth.

10 Nov 2011

Younger anxious adults tend to immediately avoid anti-smoking videos

Younger adults who generally feel anxious tend to immediately avoid anti-smoking videos that describe how cigarettes can lead to death, disease and harm to others, before considering the message, according to a new University of Georgia study.

10 Nov 2011

GHSU expert to again coordinate two national diabetes initiatives

Two national efforts supporting diabetes research will again be coordinated by a Georgia Health Sciences University bioinformatics expert.

10 Nov 2011

UC Riverside professor to co-lead '1000 Fungal Genomes' project

Jason Stajich, an assistant professor of plant pathology and microbiology at the University of California, Riverside, is a member of an international research team that, in collaboration with the Joint Genome Institute of the U.S. Department of Energy, has embarked on a five-year project to sequence 1000 fungal genomes from across the Fungal Tree of Life.

10 Nov 2011

Helping others helps adolescent helpers reduce cravings for alcohol and drugs

A new study of teens undergoing substance abuse treatment finds helping others helps the adolescent helper by reducing cravings for alcohol and drugs, a major precipitator of relapse.

9 Nov 2011

Online platform for automatic analysis of microscopic image data

Under the microscope lies a specimen of a liver. Deep in concentration, a student is analyzing the structure of the tissue when the university official asks her to finish up - the lab is about to close. This is a situation that may be familiar to many students. After all, the examination of specimens is an important course component; to practice and consolidate the theory presented in lectures.

9 Nov 2011

CU Denver researchers awarded Grand Challenges Explorations grant

The University of Colorado Denver announced today that it will receive funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables researchers worldwide to test unorthodox ideas that address persistent health and development challenges.

9 Nov 2011

Adult living donor liver transplantations safe for donors

Desperately needed adult living donor liver transplantation is a safe surgery for the donor, according to researchers at Henry Ford Hospital.

9 Nov 2011

Sleep paralysis more frequent among students and psychiatric patients

What do Moby Dick, the Salem witch trials and alien abductions all have in common? They all circle back to sleep paralysis.

9 Nov 2011

Conventional definition of obesity needs to be lowered in migrant South Asians

A major study calling for levels of obesity among South Asians to be recalculated has been published by researchers from the University of Leicester.

9 Nov 2011

Researchers plan joint clinical trials of new cancer treatments, personalized therapies

The Virginia G. Piper Cancer Center at Scottsdale Healthcare is expanding its efforts to accelerate advances in cancer care with the addition of Cedars-Sinai's Samuel Oschin Comprehensive Cancer Institute in Los Angeles as a collaborator in clinical trials to develop personalized therapies that could lead to more effective cancer treatments.

9 Nov 2011

NIH announces results from first large scale study on treatment of prescription opioid addiction

People addicted to prescription painkillers reduce their opioid abuse when given sustained treatment with the medication buprenorphine plus naloxone (Suboxone), according to research published in yesterday's Archives of General Psychiatry and conducted by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

9 Nov 2011

Study explores how telework may impact work exhaustion

If you work from home part of the week as a teleworker, does it help reduce work exhaustion caused by juggling work and family commitments? The answer may depend on the level of conflict you have between work and home and your ability to recharge your batteries adequately, according to Professor Timothy Golden, from the Rensselaer Polytechnic Institute in Troy, NY.

9 Nov 2011

Treatments can help most HCM patients

Most of the 600,000 Americans with hypertrophic cardiomyopathy (HCM) -- a genetic heart muscle disease -- can live normal life spans, according to the first science-based guideline for diagnosing and treating this disorder.

9 Nov 2011

Four-year kala azar treatment study launched in India, Bangladesh

"A four-year test of drugs to treat a widespread parasitic disease called kala azar was announced on Monday by the governments of India and Bangladesh, Doctors Without Borders, the Drugs for Neglected Diseases Initiative [DNDi] and other groups," the New York Times reports.

9 Nov 2011