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Obesity linked to colorectal adenoma risk

A meta-analysis has shown that increasing adiposity shows a direct relationship with the development of adenomas in the colon– helping to shed light on the link between obesity and colorectal cancer.

10 Jul 2012

As needed ranibizumab effective for exudative AMD

Study findings suggest that ranibizumab significantly improves visual acuity in patients with exudative age-related macular degeneration when administered initially on a monthly basis and followed by re-treatment if needed.

10 Jul 2012

One-quarter of ITP patients achieve 5-year treatment-free response

Approximately 25% of patients with immune thrombocytopenia purpura who receive treatment with rituximab maintain a treatment-free response lasting for at least 5 years, study findings suggest.

10 Jul 2012

Neuroprotective effects underpin fingolimod benefits in MS

Fingolimod therapy reduces inflammatory activity and tissue loss in the brains of patients with multiple sclerosis, shows further analysis of the FREEDOMS trial.

10 Jul 2012

Poor vaccine uptake blamed for polio rise in Pakistan, Afghanistan

The number of cases of poliomyelitis per year in Pakistan and Afghanistan has more than doubled since 2006 despite improvements in available vaccine efficacy, show study findings in The Lancet.

10 Jul 2012

Urinary components can both boost and impair crystallization

The prevention of renal stone formation with crystallization inhibitors somewhat depends on the joint effect of such compounds in the urine matrix, rather than on the individual action of each inhibitor, report researchers.

10 Jul 2012

TV news coverage makes painful viewing

Patients with existing chronic pain syndromes experience a significant increase in pain when they are exposed to media coverage of terrorist missile attacks, researchers say.

10 Jul 2012

High ferritin warns of bone loss

Individuals with high levels of ferritin, an indicator of iron stores within the body, have accelerated bone loss at the proximal femur, Korean researchers report.

10 Jul 2012

Effective ketoprofen dose identified for pig endotoxins

Compared with tap water, treatment with ketoprofen significantly reduces the rectal temperature and total clinical scores among pigs challenged with the Escherichia coli endotoxin, report researchers.

10 Jul 2012

Ozone concerns aired over effect on cardiac biomarkers

Exposure to ozone for as little as 2 hours could induce physiologic changes associated with cardiovascular disease, say US researchers.

10 Jul 2012

Racial differences in hospice use revealed

Study results show that while hospice use by Medicare beneficiaries with heart failure increased in the USA over the period 2000 through 2008, non-White patients were less likely to enroll than their White counterparts.

10 Jul 2012

Family history of schizophrenia, BD increases autism risk

A history of schizophrenia or bipolar disorder in first-degree relatives is associated with a significantly increased risk for autism spectrum disorders, study results suggest.

10 Jul 2012

TNF-α levels linked to lithium response in BD patients

Patients with bipolar disorder who have a poor response to lithium treatment have significantly higher serum levels of tumor necrosis factor-α than those with a good response, researchers report.

10 Jul 2012

Steroid receptor gene variant impacts metabolic health

A variant in the glucocorticoid receptor gene may be associated with increased body fat and insulin resistance, show study findings.

10 Jul 2012

Broken heart syndrome arms against epinephrine high

Takotsubo cardiomyopathy, or “broken heart syndrome,” may actually protect the heart from very high levels of epinephrine, suggest results from an animal study.

10 Jul 2012

Booklet simplifies dizziness care

Giving patients with chronic dizziness a simple booklet to help them learn vestibular rehabilitation exercises is a highly cost-effective alternative to the usual way of treating them, report researchers in the BMJ.

10 Jul 2012

Peritoneal dialysis patients who live remotely face high peritonitis risk

Patients with renal disease who live more than 100 km from their nearest peritoneal dialysis unit face a higher risk for peritonitis, particularly with Staphylococcus aureus, than their peers who live closer, results of a large Australian study show.

10 Jul 2012

Peripheral arterial disease predicts mortality in TAVI patients

Patients with severe aortic stenosis who undergo transcatheter aortic valve implantation are at particularly high risk for complications and death if they also have concomitant peripheral arterial disease, study results show.

10 Jul 2012

Brain activity patterns may aid mental illness diagnosis

The identification of neural activity patterns in response to facial expressions of emotion may help in the diagnoses of mental illness, say researchers.

10 Jul 2012