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UT Southwestern Medical Center researchers identify novel chemical compounds with anti-malarial activity

As part of a multicenter study, UT Southwestern Medical Center researchers have identified a series of chemical compounds that might serve as starting points for the identification of new classes of anti-malarial drugs.

26 May 2010

RSV appears to be predominant among Kenyan children hospitalized with severe pneumonia: Study

Among infants and children hospitalized in Kenya with severe pneumonia, respiratory syncytial virus appears to be the predominant virus detected, according to a study in the May 26 issue of JAMA.

26 May 2010

Consequences of secrecy in medicine

No one knows how many mothers' and babies' lives have been saved by the obstetrical forceps. This device has been part of the standard equipment of every maternity room for about 250 years. However, a shadow lies over the success story: after the Chamberlen brothers developed the device at the beginning of the 17th century, the brothers and their descendants used it for 3 generations, but kept it a secret from other obstetricians.

26 May 2010

Medication for mood disorders common among youth: Study

Living with a mental illness can be a tough experience for adults, but with the increasing numbers of youth diagnosed and taking medications for mood disorders, it can become a time of isolation, according to a study from Case Western Reserve University Mandel School of Applied Social Sciences.

26 May 2010

Research findings on pediatric ILD published online in PED

An insightful and in-depth presentation of the most up-to-date clinical and research findings and historical perspectives on pediatric interstitial lung disease is presented in a special issue published online ahead of print in Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal published by Mary Ann Liebert, Inc.

26 May 2010

Researchers describe carcinogenic effects of EDCs

Longtime environmental health researchers at Tufts University School of Medicine describe the carcinogenic effects of endocrine-disrupting chemicals, ubiquitous chemicals that have hormone-like effects in the body. In a review article published online May 25 in Nature Reviews Endocrinology, the researchers express the need for more complex strategies for studying how these chemicals affect health but report that ample evidence already supports changing public health and environmental policies to protect the public from exposure to EDCs.

26 May 2010

ReVision Optics receives $35 million in capital funding

ReVision Optics, Inc. (RVO), an ophthalmic surgical products company, recently received $35 million in capital funding. The Lake Forest, Calif.-based firm specializes in the research, development and manufacturing of custom products to correct and maintain near vision.

26 May 2010

NIDDK awards Albert Einstein College of Medicine $9.5M for continuation of Diabetes Research and Training Center

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) has awarded Albert Einstein College of Medicine of Yeshiva University a five-year, $9.5 million grant for the continuation of its Diabetes Research and Training Center (DRTC). The DRTC was also awarded a $632,000 supplemental grant for equipment and additional pilot and feasibility studies through the American Recovery and Reinvestment Act (ARRA), bringing total NIH support to $10,177,000.

26 May 2010

NASH-induced cirrhosis is greater risk factor for HCC: Cleveland Clinic study

A study conducted by researchers at the Cleveland Clinic finds that patients suffering from cirrhosis preceded by nonalcoholic steatohepatitis are at an equal risk of developing hepatocellular carcinoma than those who develop cirrhosis resulting from hepatitis C virus. Results of this study appear in the June issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

26 May 2010

HDL cholesterol can transform from good to bad actor in heart-disease process

We've all heard about the importance of raising HDL, or the so-called "good" cholesterol, and lowering LDL, or "bad" cholesterol, to improve heart health. While we've come to assume HDL cholesterol is an inherently good thing, a new study shows that for a certain group of patients, this is not always the case. The study is the first to find that a high level of the supposedly good cholesterol places a subgroup of patients at high risk for recurrent coronary events, such as chest pain, heart attack, and death.

26 May 2010

Osteopathic manipulative medicine reduces length of hospital stays for pneumonia patients: Research

Older patients battling pneumonia spent less time in the hospital when treated using osteopathic manipulative medicine - a drug-free form of hands-on medical care focusing on increasing muscle motion - in addition to conventional care, recently published research shows.

26 May 2010

Heptares Therapeutics, O2h extend multi-FTE -synthetic chemistry services collaboration

Executives from Heptares Therapeutics (Welwyn Garden City, UK) and O2h (Cambridge, UK) announced today an extension of the agreement under which O2h provides multi-FTE -synthetic chemistry services to support discovery programmes at Heptares.

26 May 2010

Five Prime Therapeutics, Fast Forward partner to develop Multiple Sclerosis therapeutic candidate

Five Prime Therapeutics, Inc., a leader in the discovery and development of innovative biologics, and Fast Forward, LLC, a subsidiary of the National Multiple Sclerosis Society, today announced an alliance to fund the development of a FivePrime pre-clinical stage therapeutic candidate for treatment of Multiple Sclerosis (MS). Fast Forward will commit up to $1 million to fund the advancement of the therapeutic candidate.

25 May 2010

BIO praises Obama Administration’s dissemination of Therapeutic Discovery Project Program

The Biotechnology Industry Organization (BIO) praised the Obama Administration for its new guidance, released today, that will lead to many small biotechnology companies receiving needed funding to support critical on-going research and development programs. The guidance document initiates the Therapeutic Discovery Project Program (TDPP), which was created by the Patient Protection and Affordable Care Act signed into law by President Obama on March 23.

25 May 2010

Researchers study how hematopoietic cells react when Epo levels increase

Our body reacts to blood loss by stimulating the production of red blood cells (erythrocytes). The cells of the hematopoietic (blood-forming) system in the bone marrow do so upon receipt of a signal by a hormone called erythropoietin, or Epo for short. This hormone is produced mainly by the kidney that increases the Epo level by up to a thousand-fold as a response to falling oxygen saturation of the blood.

25 May 2010

Masimo PVI identifies patients at high risk for developing severe hypotension during anesthesia induction

Masimo, the inventor of Pulse CO-Oximetry and Measure-Through Motion and Low Perfusion pulse oximetry, announced today that a new clinical study published in the May 2010 issue of Acta Anaesthesiologica Scandinavica shows that Masimo pleth variability index can be used to help clinicians assess risk for mean arterial pressure decreases and subsequent hypotension during anesthesia administration.

25 May 2010

Anti-aging supplements may prevent decline in physical function: Researchers

Anti-aging supplements made up of mixtures might be better than single compounds at preventing decline in physical function, according to researchers at the University of Florida's Institute on Aging. In addition, it appears that such so-called neutraceuticals should be taken before very old age for benefits such as improvement in physical function.

25 May 2010

Excessive amounts of HSP10 inside mitochondria can halt body's ageing process: Researchers

HSP10 (Heat Shock Protein), helps monitor and organise protein interactions in the body, and responds to environmental stresses, such as exercise and infection, by increasing its production inside cells. Researchers at Liverpool, in collaboration with colleagues at the University of California, found that excessive amounts of HSP10 inside mitochondria - 'organs' that act as energy generators in cells - can halt the body's ageing process by preserving muscle strength.

25 May 2010

RainDance Technologies increases commercial activities in Europe with series of technology seminars

RainDance Technologies, Inc., a leading provider of innovative microdroplet-based solutions for human health and disease research, today announced it is increasing its commercial activities in Europe beginning with a series of technology seminars during the week of 24 May 2010.

25 May 2010

New research finding may change direction of vaccine research for M. tuberculosis

Scientists at NYU Langone Medical Center have discovered that the strategy of "immune evasion" common to many viruses, bacteria and parasites, is uncommon to M. tuberculosis where the antigens remain strikingly unchanged and homogenous. The study published in Nature Genetics on May 23, 2010, suggests that M. tuberculosis antigens do not mutate because they hope to be recognized by the body's immune system- perhaps because the host immune mechanism that leads to the typical lung destruction and cough can contribute to the spread of the disease.

25 May 2010

Medical Research News

UT Southwestern Medical Center researchers identify novel chemical compounds with anti-malarial activity

RSV appears to be predominant among Kenyan children hospitalized with severe pneumonia: Study

Consequences of secrecy in medicine

Medication for mood disorders common among youth: Study

Research findings on pediatric ILD published online in PED

Researchers describe carcinogenic effects of EDCs

ReVision Optics receives $35 million in capital funding

NIDDK awards Albert Einstein College of Medicine $9.5M for continuation of Diabetes Research and Training Center

NASH-induced cirrhosis is greater risk factor for HCC: Cleveland Clinic study

HDL cholesterol can transform from good to bad actor in heart-disease process

Osteopathic manipulative medicine reduces length of hospital stays for pneumonia patients: Research

Heptares Therapeutics, O2h extend multi-FTE -synthetic chemistry services collaboration

Five Prime Therapeutics, Fast Forward partner to develop Multiple Sclerosis therapeutic candidate

BIO praises Obama Administration’s dissemination of Therapeutic Discovery Project Program

Researchers study how hematopoietic cells react when Epo levels increase

Masimo PVI identifies patients at high risk for developing severe hypotension during anesthesia induction

Anti-aging supplements may prevent decline in physical function: Researchers

Excessive amounts of HSP10 inside mitochondria can halt body's ageing process: Researchers

RainDance Technologies increases commercial activities in Europe with series of technology seminars

New research finding may change direction of vaccine research for M. tuberculosis

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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