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Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML

Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today.

29 Mar 2009

Facial flushing in East Asians who consume alcohol linked to esophageal cancer risks

About one-third of people of Chinese, Japanese and Korean descent have an enzyme deficiency that causes their face to flush when they drink alcohol, a trait that puts them at a higher risk for developing esophageal cancer, according to a study published in the journal PLoS Medicine, Reuters Health reports.

25 Mar 2009

Fructose metabolism by the brain increases food intake and obesity

The journal Biochemical and Biophysical Research Communications (BBRC), published by Elsevier, will publish an important review this week online, by M. Daniel Lane and colleagues at Johns Hopkins, building on the suggested link between the consumption of fructose and increased food intake, which may contribute to a high incidence of obesity and Type 2 diabetes.

25 Mar 2009

Lifeless cells ensure sharp vision

Seemingly dead cells perform a surprising task in the lens of a fish eye. Every morning and evening they change the lens's capacity to refract light in order to enhance color perception during the day and night vision when it's dark. This is shown in new research from Lund University in Sweden.

25 Mar 2009

The egg makes sure that sperm don't get too old

In contrast to women, men are fertile throughout life, but research at the Sahlgrenska Academy, University of Gothenburg, Sweden, has now shown that a fertilising sperm can get help from the egg to rejuvenate. The result is an important step towards future stem cell therapy.

25 Mar 2009

Researchers decipher blood stem cell attachment, communication

Researchers at the National Institutes of Health have deciphered a key sequence of events governing whether the stem cells that produce red and white blood cells remain anchored to the bone marrow, or migrate into the circulatory system.

25 Mar 2009

Effect of neighborhood context and smoking prevalence among Asian Americans

Does the neighborhood where you live play a role in whether you become a smoker?

24 Mar 2009

Discovery of a protein link to wound healing

Diabetes and eczema may appear to be two completely unrelated diseases.

24 Mar 2009

Sodas increase risk for coronary heart disease

Regular consumption of sugary beverages such as soda put women at a higher risk for coronary heart disease.

24 Mar 2009

Study helps identify college drinkers at risk for adult alcohol abuse

College students who are problem drinkers using alcohol to cope with personal problems and boost self-confidence are more likely to continue excessive drinking into adulthood, a recent study suggests.

24 Mar 2009

Diabetic retinopathy more prevalent in South Asians and occurs earlier

South Asians with type 2 diabetes are significantly more at risk of losing their eyesight and losing it at an earlier age, compared to White Europeans with the same condition.

24 Mar 2009

Recently identified genetic heart disorder often deadly for young patients

A study that included young patients with a recently recognized rare type of cardiomyopathy (a disorder of the heart muscle) linked to a genetic mutation finds that progression of this disease may be rapid and often results in early death, according to a study in the March 25 issue of JAMA.

24 Mar 2009

Scientists develop new agents to fight superbugs

Experts from Queen's University Belfast have developed new agents to fight MRSA and other hospital-acquired infections that are resistant to antibiotics.

24 Mar 2009

Omega-3 fatty acids appear protective against advanced prostate cancer

Omega-3 fatty acids appear protective against advanced prostate cancer, and this effect may be modified by a genetic variant in the COX-2 gene, according to a report in Clinical Cancer Research , a journal of the American Association for Cancer Research.

24 Mar 2009

Older adults concern for personal health linked to walking difficulty

Older adults who worry about their health engage in less physical activity, and those who participate in less activity are more likely to report having difficulty walking, according to a new study.

24 Mar 2009

Trial looks at intensive insulin therapy risks

Intensive insulin therapy is used in many intensive care units around the world as a means to tightly regulate blood sugar.

24 Mar 2009

New test for breast cancer metastasis

Scientists at Albert Einstein College of Medicine of Yeshiva University have previously shown that the co-mingling of three cell types can predict whether localized breast cancer will spread throughout the body.

24 Mar 2009

New study set to change how critically ill patients are treated

The current practice of intensively lowering blood glucose in critically ill patients increases the risk of death by 10%.

24 Mar 2009

Discovery of 'master regulator' gene for skin development

Researchers at Oregon State University have found one gene in the human body that appears to be a master regulator for skin development, in research that could help address everything from skin diseases such as eczema or psoriasis to the wrinkling of skin as people age.

24 Mar 2009