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Certain proteins, genes play key role in regenerating lost body parts: Research

Another option may be on the horizon for patients who lose limbs due to war, accident, or disease. Instead of using artificial legs or arms, patients actually may regrow their own missing limbs. An article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine, focuses on research efforts to turn the long-standing dream of human limb regeneration into reality.

5 Aug 2010

Amputation can be prevented when patients are treated by podiatric physicians: Study

Amputation, one of the most devastating and costly consequences of diabetes, can be prevented when patients are treated by podiatric physicians. That's the finding of a national, large-scale study co-authored by Dr. James Wrobel, DPM, MS, Associate Professor of Medicine at Rosalind Franklin University of Medicine and Science.

5 Aug 2010

Injecting PAP may reduce chronic pain: Research

A study published in the Aug. 4, 2010 issue of the Journal of Neuroscience introduces an enzyme that could pack a big punch in the battle against chronic pain. Its name is prostatic acid phosphatase or PAP for short. According to researchers at the University of North Carolina at Chapel Hill, PAP blocks pain in animal models by siphoning off a molecule called PIP2—a critical component of the chemical cascade behind chronic pain.

5 Aug 2010

Scientists identify tiny RNA molecule that increases blood stem cells

Investigators have identified a new mechanism that controls the number of hematopoietic stem cells - cells that give rise to all blood and immune system cells. In a report in the online Early Edition of Proceedings of the National Academy of Sciences, researchers from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute identify a tiny RNA molecule that increases the number of these blood stem cells, an advance that may improve treatment of blood system cancers.

5 Aug 2010

Excess maternal weight gain predicts high birth weight: Research

Expectant mothers who gain large amounts of weight tend to give birth to heavier infants who are at higher risk for obesity later in life. But it's never been proven that this tendency results from the weight gain itself, rather than genetic or other factors that mother and baby share. A large population-based study from Children's Hospital Boston, looking at two or more pregnancies in the same mother, now provides evidence that excess maternal weight gain is a strong, independent predictor of high birth weight.

5 Aug 2010

Ferroportin levels are strong predictors of propensity for breast cancer recurrence: Study

A new study by researchers at Wake Forest University Baptist Medical Center (WFUBMC) may soon help to spare some women with breast cancer from having to undergo invasive and toxic treatments for their disease.

5 Aug 2010

Sigma-Aldrich, NHLBI and BU collaborate in atherosclerotic cardiovascular disease research

Sigma-Aldrich® today announced it has entered into an agreement with the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, and Boston University (BU) to develop methods to measure several potential biomarkers of atherosclerotic cardiovascular disease (CVD) using plasma samples from the NHLBI's Framingham Heart Study (FHS), one of the most prestigious clinical studies in medicine. Funding for the project is provided by the NHLBI to Sigma-Aldrich under a research subaward agreement with BU.

5 Aug 2010

SORT1 pathway holds promise as new target for therapeutic intervention for LDL cholesterol reduction

The true power of genomic research lies in its ability to help scientists understand biological processes, particularly those that - when altered - can lead to disease. This power is demonstrated dramatically in a pair of papers published today in the journal Nature. In the first, a global team of researchers describes 95 different variations across the genome that contribute in different degrees to alterations in blood cholesterol and triglyceride levels in multiple human populations. In the second report, close examination of just one of these common variants not only reveals the involvement of an unexpected genetic pathway in lipid metabolism but also provides a blueprint for using genomic findings to unravel biological connections between lipid levels and coronary heart disease.

5 Aug 2010

Certain human leukemias can be treated by targeting stem-cell microRNAs: Research

Hematopoietic stem cells provide the body with a constant supply of blood cells, including the red blood cells that deliver oxygen and the white blood cells that make up the immune system. Hematopoietic-or blood-stem cells must also make more copies of themselves to ensure that they are present in adequate numbers to provide blood throughout a person's lifetime, which means they need to strike a delicate balance between self-renewal and development into mature blood-cell lineages. Perturb that balance, and the result can be diseases such as leukemia and anemia.

5 Aug 2010

Thinking of God reduces distress to anxiety-provoking mistakes: Study

Thinking about God may make you less upset about making errors, according to a new study published in Psychological Science, a journal of the Association for Psychological Science. The researchers measured brain waves for a particular kind of distress-response while participants made mistakes on a test. Those who had been prepared with religious thoughts had a less prominent response to mistakes than those who hadn't.

5 Aug 2010

Simmons Comprehensive Cancer Center at UT Southwestern attains National Cancer Institute designation

The Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center has attained National Cancer Institute (NCI) designation, an elite distinction held by only the top-tier cancer centers nationwide.

5 Aug 2010

Study links sea sponge genome sequence with first animals and cancer

The sponge, which was not recognized as an animal until the 19th century, is now the simplest and most ancient group of animals to have their genome sequenced. In a paper appearing in the August 5 issue of the journal Nature, a team of researchers led by Daniel Rokhsar of the University of California, Berkeley, and the Department of Energy's Joint Genome Institute (JGI), report the draft genome sequence of the sea sponge Amphimedon queenslandica and several insights the genome gives into the origins of both the first animals and cancer.

5 Aug 2010

Research examines effects of orthostatic hypotension in adults, children

A simple variation to the tried and true method of checking blood pressure can reveal startling information about both older and younger persons, new research suggests.

4 Aug 2010

New study of breast cancer survivors may help physicians ease side effect of treatments

A new study of breast cancer survivors may help physicians ease a common side effect of cancer treatments. The collaborative research by Eva Sevick, Ph.D., Director of the Center for Molecular Imaging at the University of Texas Health Science Center in Houston, and Caroline Fife, M.D., Director of the Memorial Herman Wound Care Clinic at UTHSC, could bring relief to millions.

4 Aug 2010

Blood coagulation, antimicrobial defence processes are functionally coupled: Research

The adaptive immune system can recognize and respond specifically to particular infectious agents. But the first line of defence against pathogens is the so-called innate immune system. This system reacts to invaders by initiating unspecific inflammatory responses which attract various types of specialized cells such as neutrophils to the site of the incursion.

4 Aug 2010

Targacept licenses Cornerstone technology for inflammatory disorders program

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics(TM), today announced that it has added to its program for inflammatory disorders by entering into an exclusive worldwide license agreement with Cornerstone Therapeutics Inc. The agreement grants Targacept rights to Cornerstone's NNR-based patents, as well as its library of preclinical compounds that act on the alpha7 or other nicotinic receptors.

4 Aug 2010

MabCure files provisional patent application for ovarian cancer diagnostic antibodies

Biotechnology company MabCure, Inc. today announced the company has filed a provisional patent application for its ovarian cancer diagnostic antibodies with the U.S. Patent and Trademark Office. The filing was based on positive results of a recent study that showed MabCure's tumor-specific monoclonal antibodies (MAbs) successfully identified ovarian cancer in blood (94 percent) and distinguished it from benign tumors of the ovaries or healthy blood obtained from men and women.

4 Aug 2010

Definiens launches Tissue Studio 2.0 image analysis software for digital pathology

Definiens today announced the introduction of Definiens Tissue Studio™ 2.0, the latest version of the company's leading image analysis software for digital pathology.

4 Aug 2010

Achievement of tenth milestone triggers EUR 2.5 million payment from Boehringer Ingelheim to Evotec

Evotec AG today announced that its research alliance with Boehringer Ingelheim has reached a milestone, triggering a payment of EUR 2.5 million to Evotec. The milestone reached was the selection of a candidate compound for pre-development studies in an inflammation and immunology programme.

4 Aug 2010

Researchers identify TACI; MyD88 activates immune system against infection

Researchers from Mount Sinai School of Medicine have found a new mechanism that explains how certain immune cells are activated to create protective antibodies against infections or pathological antibodies such as those present in autoimmune diseases like lupus and rheumatoid arthritis. The research is published online in the September issue of Nature Immunology.

4 Aug 2010

Medical Research News

Certain proteins, genes play key role in regenerating lost body parts: Research

Amputation can be prevented when patients are treated by podiatric physicians: Study

Injecting PAP may reduce chronic pain: Research

Scientists identify tiny RNA molecule that increases blood stem cells

Excess maternal weight gain predicts high birth weight: Research

Ferroportin levels are strong predictors of propensity for breast cancer recurrence: Study

Sigma-Aldrich, NHLBI and BU collaborate in atherosclerotic cardiovascular disease research

SORT1 pathway holds promise as new target for therapeutic intervention for LDL cholesterol reduction

Certain human leukemias can be treated by targeting stem-cell microRNAs: Research

Thinking of God reduces distress to anxiety-provoking mistakes: Study

Simmons Comprehensive Cancer Center at UT Southwestern attains National Cancer Institute designation

Study links sea sponge genome sequence with first animals and cancer

Research examines effects of orthostatic hypotension in adults, children

New study of breast cancer survivors may help physicians ease side effect of treatments

Blood coagulation, antimicrobial defence processes are functionally coupled: Research

Targacept licenses Cornerstone technology for inflammatory disorders program

MabCure files provisional patent application for ovarian cancer diagnostic antibodies

Definiens launches Tissue Studio 2.0 image analysis software for digital pathology

Achievement of tenth milestone triggers EUR 2.5 million payment from Boehringer Ingelheim to Evotec

Researchers identify TACI; MyD88 activates immune system against infection

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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