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University of Arizona spin-off investigates DNA damage to human skin

Niadyne, Inc., a Tucson-based spin-off biopharmaceutical company co-founded by two University of Arizona professors, has received a Small Business Innovation Research grant of nearly $750,000 to continue investigating the prevention of DNA damage to human skin

22 Sep 2004

NIH opens new hospital totally dedicated to clinical research

This new hospital totally dedicated to clinical research — research involving patients — is the most significant addition to the NIH campus in more than 50 years and provides a unique opportunity for scientists, clinicians, and patients to study and conquer both chronic and acute disease in the 21st century.

22 Sep 2004

Fish oils appear to reduce breast cancer risk

Researchers who found that fish oils appear to reduce breast cancer risk have now discovered that the oils may especially benefit women with particular genetic makeups.

21 Sep 2004

Experimental drug PKC412 may be the key to treating myeloproliferative disease

Scientists at Dana-Farber Cancer Institute and Brigham and Women's Hospital have prolonged the lives of mice with a rare blood disorder by using an experimental drug that blocks signals promoting runaway growth of blood cells.

21 Sep 2004

New gene therapy technique may help treat Alzheimer's disease

Investigators at Rush University Medical Center have successfully initiated a new technique that uses gene therapy to deliver nerve growth factor into regions of the brain where neurons are degenerating, in order to prevent cell death and reverse cell atrophy, two hallmarks of Alzheimer's disease.

21 Sep 2004

Evidence pointing to chronic cellular inflammation as the precursor of heart disease and diabetes

Endocrinologists from the University at Buffalo are providing one more link in the growing chain of evidence pointing to chronic cellular inflammation as the precursor of heart disease and diabetes.

21 Sep 2004

Novel strategy for stimulating the production of utrophin

Researchers at the University of Pennsylvania School of Medicine report a novel strategy for stimulating the production of utrophin – an important muscle protein in young mice – for muscular dystrophy therapy.

21 Sep 2004

Stress response proteins offer a promising target for a novel drug guidance system

Their study, published in the September issue of the journal Cancer Cell, demonstrates how researchers can find protein tags that are unique to cancer cells and then tweak a drug delivery system to zero in on those tags and destroy the cells.

21 Sep 2004

HER-2 cell surface receptors tun on genes associated with carcinogenesis

Researchers at The University of Texas M. D. Anderson Cancer Center now have evidence that receptors found on tumors that were believed to function only on the surface of cells can actually switch on genes inside a cell's nucleus, thus promoting cancer development in two distinct ways.

21 Sep 2004

Laser therapy and tacrolimus ointment best for vitiligo

Patients with vitiligo, a skin disorder characterized by patches of white, or de-pigmented skin, had better repigmentation of these patches when they were treated with a combination of laser therapy and tacrolimus ointment than patients treated with laser therapy alone

21 Sep 2004

Obesity makes surgery more difficult and risky

Critically injured obese trauma patients have higher rates of death than nonobese trauma patients, according to an article in the September issue of The Archives of Surgery, one of the JAMA/Archives journals.

21 Sep 2004

Streptococcus bacteria uses sword and shield to fight white blood cells

A single gene called cylE within the important bacterial pathogen Group B Streptococcus (GBS), controls two factors that act together as a “sword” and “shield” to protect the bacteria from the killing effects of the immune system’s white blood cells

21 Sep 2004

A low salt diet can be extremely dangerous for elderly people

Professor Füsgen presented his findings at the European Geriatrics Congress in Vienna, which ended yesterday (September 19). They show that the symptoms of hyponatraemia (low sodium level in the blood), which are tiredness, difficulty in concentrating and loss of balance, can develop into confusion and even coma if left untreated.

20 Sep 2004

New imaging analysis techniques to probe causes of dyslexia

Using sophisticated new software that integrates a variety of imaging methods, Wake Forest University Baptist Medical Center researchers will probe the mystery of what causes dyslexia with a four-year, $2.3 million grant from the National Institutes of Health.

20 Sep 2004

Certain cancers might one day be cured without the use of toxic chemotherapy and radiation

The eradication of brain tumors in mice following treatment with a novel drug suggests that certain cancers might one day be cured without the use of toxic chemotherapy and radiation.

20 Sep 2004

New anti-inflammatory strategy for cancer therapy

A new strategy for cancer therapy, which converts the tumor-promoting effect of the immune system’s inflammatory response into a cancer-killing outcome, is suggested in research findings by investigators at the University of California, San Diego (UCSD) School of Medicine.

20 Sep 2004

Research may provide a better understanding of the mental retardation observed in Cri-du-Chat Syndrome

By specifically deleting the adhesion protein d-catenin, which is found exclusively in the brain, researchers at UCLA have found evidence that loss of d-catenin produces severe cognitive and synaptic dysfunction.

20 Sep 2004

Vanilla may become a drug to treat sickle cell disease

In addition to its popular role in flavoring ice cream, fudge and cake frosting, vanilla may have a future use as a medicine. Recent laboratory research has strengthened the possibility that a form of vanilla may become a drug to treat sickle cell disease.

20 Sep 2004

Non-human primates should never be considered as source animals for any future clinical trials of animal-to-human transplantation

Australia’s leading health advisory body, the National Health and Medical Research Council, says there should be a five-year moratorium on any clinical research into animal-to-human whole organ transplants in Australia.

20 Sep 2004

Breakthrough in spinal regeneration research

University of Queensland researchers are claiming a breakthrough in spinal regeneration research with the discovery of a molecule that blocks regrowth of damaged nerve processes.

20 Sep 2004