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Researchers examine role of high cholesterol in prostate cancer

Current research suggests that lowering cholesterol may block the growth of prostate tumors.

23 Feb 2009

Human stem cells provide a new model for Lou Gehrig's disease

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating condition in which motor neuron degeneration causes progressive loss of movement and muscle tone, leading to death.

23 Feb 2009

Discovery of gene that controls the production of tooth enamel

Researchers have identified the gene that ultimately controls the production of tooth enamel, a significant advance that could some day lead to the repair of damaged enamel, a new concept in cavity prevention, and restoration or even the production of replacement teeth.

23 Feb 2009

Enhanced skin cancer risk linked to defects in cellular aging controls

Cell lifespan is limited by telomeres, DNA sequences that cap chromosomes and control the number of times a cell may be copied.

23 Feb 2009

Statins may lessen brain function

Research by an Iowa State University scientist suggests that cholesterol-reducing drugs known as statins may lessen brain function.

23 Feb 2009

Researchers develop 'wireless' activation of brain circuits

Traditionally, stimulating nerves or brain tissue involves cumbersome wiring and a sharp metal electrode.

23 Feb 2009

Redesign technique for proteins

Proteins are widely viewed as a promising alternative to synthetic chemicals in everything from medications to hand lotion.

23 Feb 2009

New understanding of how anger can ventricular arrhythmias

New research published in the March 3, 2009, issue of the Journal of the American College of Cardiology finds that anger-induced electrical changes in the heart can predict future arrhythmias in patients with implantable cardioverter-defibrillators (ICDs).

23 Feb 2009

Aneurysms do not occur earlier in second generation

People whose parents or aunts and uncles have had a brain aneurysm are more likely to have one themselves, indicating that genetic risk factors passed down by generation are responsible.

23 Feb 2009

Gold nanoparticles improve gene regulation

Investigators at Northwestern University have found that packing small interfering RNA (siRNA) molecules onto the surface of a gold nanoparticle can protect siRNAs from degradation and increase their ability to regulate genes involved in cancer. As a result of this discovery, cancer researchers have at their disposal a relatively straightforward method of delivering these potent gene-regulating agents into targeted cells.

23 Feb 2009

Targeted nanospheres find, penetrate, then fuel burning of melanoma

Hollow gold nanospheres equipped with a targeting peptide find melanoma cells, penetrate them deeply, and then cook the tumor when bathed with near-infrared light. When heated with lasers, the actively targeted hollow gold nanospheres did eight times more damage to melanoma tumors in mice than did the same nanospheres that gathered less directly in the tumors.

23 Feb 2009

Nanoparticles detect dying cancer cells

Two years ago, researchers at the University of South Australia discovered a new molecular marker specific for chemotherapy-induced cancer cell death. Now, those same investigators have used this marker to develop an imaging agent that can pinpoint tumor cell death using magnetic resonance imaging.

23 Feb 2009

Basis of immunity to oral thrush, common in AIDS, identified by UB researchers

Oral thrush, a hallmark symptom in AIDS patients, is caused by a type of yeast that grows unchecked in people with weakened immune systems, and appears in colonies of white patches in the mouth.

23 Feb 2009

Statins can stimulate cardiac muscle cell regeneration, improve heart function

Statins, used widely to treat elevated cholesterol, have been shown to prevent progression of coronary narrowing and to have other beneficial effects on the heart, such as reducing inflammation, that are independent of cholesterol.

23 Feb 2009

Suppressing cancer with a master control gene

Starting with the tiny fruit fly and then moving into mice and humans, researchers at VIB and K. U. Leuven show that expression of the same gene suppresses cancer in all three organisms. Reciprocally, switching off the gene - called Ato in flies and ATOH1 in mammals - leads to cancer.

23 Feb 2009

People who start smoking before age 17 increase risk for multiple sclerosis

People who start smoking before age 17 may increase their risk for developing multiple sclerosis (MS), according to a study released today that will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009.

22 Feb 2009

Tiny cell cultivation chamber of silicon plastic opens new potential in tumor research

Researchers at Uppsala University have developed a new tool that makes it possible to study the signals in the body that control the generation of blood vessels.

22 Feb 2009

Scientists identify lab-made proteins that neutralize multiple strains of seasonal and pandemic flu

Scientists have identified a small family of lab-made proteins that neutralize a broad range of influenza A viruses, including the H5N1 avian virus, the 1918 pandemic influenza virus and seasonal H1N1 flu viruses.

22 Feb 2009

Scientists mine drugs database for new diabetes treatment

Scientists funded by the Biotechnology and Biological Sciences Research Council have harnessed a new drug discovery tool to identify a new player in the body's insulin secretion process.

22 Feb 2009

Scientists identify human monoclonal antibodies effective against bird flu

Researchers at the Dana-Farber Cancer Institute (Dana-Farber), Burnham Institute for Medical Research (Burnham) and the Centers for Disease Control and Prevention (CDC) have reported the identification of human monoclonal antibodies (mAb) that neutralize an unprecedented range of influenza A viruses, including avian influenza A (H5N1) virus, previous pandemic influenza viruses, and some seasonal influenza viruses.

22 Feb 2009