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Magnetic resonance studies find clear differences between the structures of infectious and non-infectious prions

Infectious proteins known as prions have been identified as the cause of "mad cow" disease (BSE). The culprits are "incorrectly folded" proteins that can "infect" healthy proteins. The molecular bases for such prion diseases are not yet fully understood.

17 Jun 2008

Life expectancy in U.S. reached record high of 78.1 years in 2006

Life expectancy for U.S. residents reached a record high of 78.1 years in 2006, compared with a previous record high of 77.8 years in 2005, according to a preliminary report released on Wednesday by the National Center for Health Statistics at CDC, the Washington Post reports. For the report, Melonie Heron, a NCHS demographer, and colleagues analyzed 95% of the death certificates collected in the 50 states and Washington, D.C., in 2006.

17 Jun 2008

Adult stem cells improve healing of broken bones

Adult stem cells improve healing of broken bones and could eventually serve as a new treatment for the 10 to 20 percent of fractures that fail to heal, according to a new study. The results were presented Monday, June 16, at The Endocrine Society's 90th Annual Meeting in San Francisco, by Froilan Granero-Molto, PhD, research associate of the University of North Carolina.

16 Jun 2008

Combined PET and CT could be valuable noninvasive tool for determining stages of ovarian cancer

Combined positron emission tomography (PET) and computed tomography (CT) scanning of patients in the early stages of ovarian cancer can enable physicians to determine whether the cancer has spread to nearby lymph nodes without having to perform surgery, according to researchers at the Society of Nuclear Medicine's 55th Annual Meeting.

16 Jun 2008

Novel agents found to inhibit growth of estrogen-dependent breast cancer cells

Researchers have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. The finding, described at a meeting of the Endocrine Society, has opened an avenue of research into new drugs to combat estrogen-dependent breast cancers.

16 Jun 2008

Gene radiotherapy system shows promise for fighting treatment-resistant cancer cells

A gene radiotherapy system that detects and treats cancer cells that are resistant to traditional forms of chemotherapy and radiation showed success in the laboratory and could eventually prove beneficial for cancer patients, according to researchers at the Society of Nuclear Medicine's 55th Annual Meeting.

16 Jun 2008

Medicines derived from cannabis: A review of adverse events

Researchers at the McGill University Health Centre (MUHC), McGill University and the University of British Columbia (UBC) determined that medical use of cannabinoids do not cause an increase in serious adverse events, but are associated with an increase in some non-serious adverse events.

16 Jun 2008

Breakthrough toxin delivery system could pave way for new antibiotic drugs

Researchers at the Hebrew University of Jerusalem have achieved a breakthrough in monitoring the toxin-delivery system of highly pathogenic bacteria - an accomplishment that could help pave the way for new drugs that will be capable of neutralizing those germs.

16 Jun 2008

Discovery of mechanisms that direct cholinergic synapse assembly between neurons in vivo

Rapid information processing in the nervous system requires synapses, specialized contact sites between nerve cells and their targets. One particular synapse type, cholinergic, uses the chemical transmitter acetylcholine to communicate between nerve cells. Cholinergic synapses are essential for normal learning and memory, arousal, attention, and all autonomic (involuntary) nervous system functions.

16 Jun 2008

Alcohol and drug misuse fuels Scottish suicide and homicide rates

Alcohol and drug misuse mean Scots are almost twice as likely to kill or take their own life compared to people living in England and Wales, research published Monday, June 16 reveals.

From The University of Manchester 16 Jun 2008

HIPAA Privacy Rule is having a negative impact on the advance of biomedical research

The privacy rule of the Health Insurance Portability and Accountability Act (HIPAA) is having a negative impact on the advance of biomedical research and the search for treatments that benefit society, says a newly-released report by the Association of Academic Health Centers (AAHC).

16 Jun 2008

Unique brain maps to assist surgery and research

Researchers from the Howard Florey Institute in Melbourne are developing new technology to create individualised brain maps that will revolutionise diagnosis of disease and enhance the accuracy of brain surgery.

16 Jun 2008

New research scotches link between heroin drought and increased amphetamine use

The suspicion on the part of some experts that Australia's heroin drought has led to an increase in amphetamine use in the last decade, has been scotched by the latest research from the New South Wales Bureau of Crime Statistics and Research.

16 Jun 2008

Pomegranate extract may provide humans with relief of chronic inflammatory conditions

Oral ingestion of pomegranate extract reduces the production of chemicals that cause inflammation suggests a study published in BioMed Central's open access Journal of Inflammation. The findings indicate that pomegranate extract may provide humans with relief of chronic inflammatory conditions.

15 Jun 2008

How to reduce obesity and cardiovascular disease risk

Changes in society are leading to a sedentary lifestyle and are causing a rise in the number of people with obesity and cardiovascular disease. This is consequently having a large impact on the health of the nation.

15 Jun 2008

Transfer of learning traced to areas of the brain

Practice makes perfect, but a question that still remains a mystery is why it is so difficult to transfer learning from a trained to an untrained task? Why are we no better at remembering faces when we have been training our memory for words? Scientists at Umea University and Karolinska Institutet in Sweden now show in the journal Science that the answer lies in the brain areas activated by each task.

15 Jun 2008

Nanoparticles trigger built-in cell-death signal to overcome drug resistance

One of the most vexing problems in treating cancer is the propensity of tumors to develop resistance to a wide range of anticancer drugs. Over 70 percent of ovarian cancer patients, for example, have drug-resistant tumors at the time of their initial diagnosis, and virtually all patients who relapse have drug-resistant tumors.

15 Jun 2008

High-content screening as a universal tool for fingerprinting of vytotoxicity of nanoparticles

As researchers develop an ever-expanding toolkit of nanoparticles for use as drug and imaging agent delivery vehicles, there is a growing need to understand how a given nanoparticle's physical and chemical properties affect biological activity and toxicity.

15 Jun 2008

Nanoparticle delivers antisense agent to tumors

A multifunctional drug delivery system consisting of a lipid-based nanoparticle, a standard anticancer drug, and a short nucleic acid designed to augment the activity of that drug has demonstrated the ability to treat drug-resistant tumor cells.

15 Jun 2008

Human tumor nanoparticles induce apoptosis of pancreatic cancer cells

Using nanoparticles made from pieces of tumor cells, investigators from Aix-Marseille University in Marseille, France, have developed a new type of anticancer agent that appears to stop tumor cell growth and proliferation.

15 Jun 2008

Medical Research News

Magnetic resonance studies find clear differences between the structures of infectious and non-infectious prions

Life expectancy in U.S. reached record high of 78.1 years in 2006

Adult stem cells improve healing of broken bones

Combined PET and CT could be valuable noninvasive tool for determining stages of ovarian cancer

Novel agents found to inhibit growth of estrogen-dependent breast cancer cells

Gene radiotherapy system shows promise for fighting treatment-resistant cancer cells

Medicines derived from cannabis: A review of adverse events

Breakthrough toxin delivery system could pave way for new antibiotic drugs

Discovery of mechanisms that direct cholinergic synapse assembly between neurons in vivo

Alcohol and drug misuse fuels Scottish suicide and homicide rates

HIPAA Privacy Rule is having a negative impact on the advance of biomedical research

Unique brain maps to assist surgery and research

New research scotches link between heroin drought and increased amphetamine use

Pomegranate extract may provide humans with relief of chronic inflammatory conditions

How to reduce obesity and cardiovascular disease risk

Transfer of learning traced to areas of the brain

Nanoparticles trigger built-in cell-death signal to overcome drug resistance

High-content screening as a universal tool for fingerprinting of vytotoxicity of nanoparticles

Nanoparticle delivers antisense agent to tumors

Human tumor nanoparticles induce apoptosis of pancreatic cancer cells

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