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New radiation-free targeted therapy detects and eliminates breast cancer tumors in mice

Combining a compound known as a gallium corrole with a protein carrier results in a targeted cancer therapy that is able to detect and eliminate tumors in mice with seemingly fewer side effects than other breast-cancer treatments, says a team of researchers from the California Institute of Technology (Caltech), the Israel Institute of Technology (Technion) and the Cedars-Sinai Medical Center.

30 Mar 2009

New, more effective nisin antibiotics combat superbugs and food diseases

Researchers at University College Cork have used bioengineering to produce a new generation of natural antibiotics that target harmful micro-organisms such as MRSA and the food-borne pathogen, Listeria monocytogenes

30 Mar 2009

Research helps explain how chronic liver damage can eventually lead to cancer

Liver damage can be triggered by various insults, including hepatitis infection or alcohol-induced cirrhosis.

30 Mar 2009

In lab supplements of lipoic acid lower triglyceride levels

Studies done with laboratory rats suggest that supplementation of their diet with lipoic acid had a significant effect in lowering triglycerides, which along with cholesterol levels and blood pressure are one of the key risk factors in cardiovascular disease.

30 Mar 2009

Mutations within a conservative region of hepatitis C virus affect therapy

At least 200 million individuals are currently infected with hepatitis C virus (HCV) worldwide.

30 Mar 2009

Multiple sclerosis associated with lower cancer risk overall

A new study shows that people with multiple sclerosis may be at a lower risk for cancer overall, but at a higher risk of developing certain types of cancer, such as brain tumors and bladder cancer.

30 Mar 2009

Mice and men should have more in common in clinical trials

Just as no two humans are the same, a Purdue University scientist has shown treating mice more as individuals in laboratory testing cuts down on erroneous results and could significantly reduce the cost of drug development.

30 Mar 2009

Melatonin may be served as a potential anti-fibrotic drug

In China, the incidence of liver cirrhosis is still high. Liver cirrhosis results from fibrosis. If treated properly at fibrosis stage, cirrhosis can be prevented.

30 Mar 2009

Is transforming growth factor-beta involved in intestinal wound healing?

Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease.

30 Mar 2009

Improving cancer therapy achieved through taste, odor intervention

Cancer and its therapies, including chemotherapy and radiotherapy, may directly alter and damage taste and odor perception, possibly leading to patient malnutrition, and in severe cases, significant morbidity, according to a Virginia Tech - Wake Forest University Comprehensive Cancer Center compilation of various existing studies.

30 Mar 2009

New model helps predict risk of new onset heart failure in the elderly

Researchers at Emory University School of Medicine created the Health ABC Heart Failure Model for predicting risk of new onset heart failure in the elderly.

30 Mar 2009

Eye cells believed to be retinal stem cells are misidentified

Cells isolated from the eye that many scientists believed were retinal stem cells are, in fact, normal adult cells, investigators at St. Jude Children's Research Hospital have found.

30 Mar 2009

Typical Western diet is a recipe for colon cancer

A typical Western diet, rich in meat and fats and low in complex carbohydrates, is a recipe for colon cancer, Professor Stephen O'Keefe from the University of Pittsburgh, USA, told the Society for General Microbiology meeting at Harrogate today (Tuesday 31 March).

30 Mar 2009

Discovery of 'lock-like' molecule may provide new ways to starve cancer tumors or prevent drug side effects

Scientists have shed new light -- literally -- on a possible way to starve cancer tumors or prevent side effects from a wide range of drugs.

30 Mar 2009

How your brain grows might come down to how your cells divide

In the April 6 issue of the Journal of Cell Biology (JCB), Lake and Sokol report that mouse protein Vangl2 controls the asymmetrical cell division and developmental fate of progenitor neurons.

30 Mar 2009

Steroids and antihistamines alleviate clopidogrel-related allergic reaction symptoms

A clinical study of cardiac patients who suffered an allergic reaction to the widely-prescribed drug clopidogrel, also known by the pharmaceutical name Plavix, found that treatment with a combination of steroids and antihistamines can alleviate the allergic reaction symptoms thereby allowing patients to remain on the drug, say doctors from Thomas Jefferson University Hospital.

30 Mar 2009