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Building stronger bones, one stem cell at a time

Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.

25 Jan 2008

New approach to gene therapy

RNA interference (RNAi) represents an innovative new strategy for using small RNA molecules to silence specific genes associated with disease processes, and a series of review articles describing the state-of-the-art and potential therapeutic applications of RNAi and microRNAs will begin with two review papers in the January 2008 issue (Volume 19, Number 1) of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc.

24 Jan 2008

Researchers identify brain's 'eureka' circuitry

Researchers have found the brain region that controls the decision to halt your midnight exploration of the refrigerator and commence enjoyment of that leftover chicken leg.

24 Jan 2008

No clear evidence that antidepressants assist in the management of chronic low back pain

Doctors commonly prescribe antidepressants for patients with low back pain for three main reasons; to relieve pain; reduce mild depression and improve a person's mood; and improve sleep.

24 Jan 2008

Nitrogen fixation process in plants to combat drought in various species of legumes

The regulation of the biological fixation of nitrogen in hydric stress conditions varies with the different species of legume plants studied.

24 Jan 2008

New method enables design, production of extremely novel drugs

A new chemical synthesis method based on a catalyst worth many times the price of gold and providing a far more efficient and economical method than traditional ones for designing and manufacturing extremely novel pharmaceutical compounds is described by its University at Buffalo developers in a review article in the current issue of Nature.

24 Jan 2008

Hawthorn extract helps the heart

Taking hawthorn extract can help control symptoms of chronic heart disease such as low abilities to work and walk, and also improve a range of heart-related measurements.

24 Jan 2008

Handwashing can reduce diarrhea episodes by about one third

Both in institutions and in communities, interventions that promote hand washing lead to significant reductions in the incidence of diarrhoea.

24 Jan 2008

Genetic difference predicts antidepressant response

Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant drugs.

24 Jan 2008

Evolutionary phenomenon in mice may explain human infertility

Scientists at the University of Liverpool have found that field mice have evolved a unique way of ensuring faster fertilisation, a phenomenon which could explain some cases of infertility in humans.

24 Jan 2008

Engineers use blood's hydrodynamics to manipulate stem, cancer cells

A tiny, implantable device has pulled adult stem cells out of a living rat with a far greater purity than any present technique.

24 Jan 2008

DNA sensors found to be an effective artificial nose

In designing artificial noses modeled after biological olfaction, the challenge has been to generate a similarly large sensor repertoire with the requisite combinatorial complexity to detect odors in the real world.

24 Jan 2008

Cranberries might help prevent urinary infections in women

Evidence supports drinking cranberry juice a familiar home remedy to treat urinary tract infection (UTI), according to a new review from Scotland.

24 Jan 2008

Cigarettes leave deadly path by purging protective genes

A University of Rochester scientist discovered that the toxins in cigarette smoke wipe out a gene that plays a vital role in protecting the body from the effects of premature aging.

24 Jan 2008

Skull survey could improve vehicle safety

Women's skulls are thicker than men's, but they both shrink slowly after we reach adulthood.

23 Jan 2008

Gene therapy for pain

Researchers in the Department of Medicine and Department of Neurosciences at Mount Sinai School of Medicine have discovered that chronic pain can be successfully treated with novel targeted gene therapy.

23 Jan 2008

New compounds for treating tuberculosis and malaria

University of Navarra PhD in chemistry researcher, Esther Vicente, has discovered new compounds active for treating tuberculosis and malaria.

23 Jan 2008

New way to boost the immune system

Queen's University immunologists have discovered how to manipulate the immune system to increase its power and protect the body from successive viral infections.

23 Jan 2008

New anticancer drugs may block HSP90-IP6K2 protein interaction involved in cell death

Johns Hopkins researchers have discovered a previously unsuspected mechanism of cell death that may afford a new way to find and develop stronger yet less-harmful anticancer drugs.

23 Jan 2008

Brain molecule from endothelial cells may be a new target for treatment of multiple sclerosis

In the February issue of Nature Immunology, the team provides fresh answers concerning the role of novel adhesion molecules in the pathogenesis of MS, a chronic autoimmune disease of the nervous system that affects approximately 55,000 young adults in Canada.

23 Jan 2008