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Increased blood pressure in older adults affects cognitive functioning

Adding another reason for people to watch their blood pressure, a new study from North Carolina State University shows that increased blood pressure in older adults is directly related to decreased cognitive functioning, particularly among seniors with already high blood pressure.

15 Dec 2008

Gene subnetworks provide new prognostic markers for breast cancer

The metastasis or spread of breast cancer to other tissues in the body can be predicted more accurately by examining subnetworks of gene expression patterns in a patient's tumor, than by conventional gene expression microarrays, according to a presentation at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

15 Dec 2008

How to build muscle mass with four and a half LIM domains 1

Mutations in FHL1 are present in several myopathies, including reducing-body myopathy (RBM), but until now, both the molecular mechanisms causing the disease, and the regular function of FHL1 in healthy tissue, remained unknown.

15 Dec 2008

Study looks at how parental age affects the mental functioning of offspring

Tel Aviv University researchers found in several consecutive studies that older dads are more likely to have boys with autism and lower IQs. Most recently, they found that the older a father's age, the greater the chance that his son will display poor social abilities as a teen.

15 Dec 2008

Psychological distress a growing heart health problem

Anyone will tell you that stress is bad for the heart. Many people also know about the toxic effects of anxiety and depression.

15 Dec 2008

Breakthrough in Alzheimer's disease screening

Australian scientists at CSIRO (Commonwealth Scientific and Industrial Research Organisation), have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer's disease.

15 Dec 2008

Sleep-related breathing disorders linked to calories burned at rest

Individuals with sleep-related breathing disorders appear to burn more calories when resting as their conditions become more severe, according to a report in the December issue of Archives of Otolaryngology-Head & Neck Surgery.

15 Dec 2008

Breast cancer genome shows instability of cancer

A newly published genome sequence of a breast cancer cell line reveals a heavily rearranged genetic blueprint involving breaks and fusions of genes and a broken DNA repair machinery, said researchers at Baylor College of Medicine in a report that appears online in the journal Genome Research.

15 Dec 2008

Blocking Myc proteins stops ovarian cancer cell cycle in its tracks

Ovarian cancer cells are "addicted" to a family of proteins produced by the notorious oncogene, MYC.

15 Dec 2008

Alzheimer's researcher explores the variety of animal models now being used in research

Very few species spontaneously develop the cognitive, behavioral and neuropathological symptoms of Alzheimer's disease (AD), yet AD research must progress at a more rapid pace than the rate of human aging.

15 Dec 2008

Pre-drinking - a new culture of intoxication

In a new report published online in the January issue of Addiction, researchers question whether current licensing policies have contributed to a rise in the phenomenon of "pre-drinking" amongst young people.

15 Dec 2008

Mechanism behind cardiac scarring discovered

In the aftermath of a heart attack, the body's own defenses may contribute to future heart failure. Authors of a new study believe they have identified a protein that plays an important role in a process that replaces dead heart muscle with stiffening scar tissue. The researchers are hopeful that the findings will lead to the development of new therapies to prevent this damage.

15 Dec 2008

Researchers solve failed vaccine mystery

Research led by Johns Hopkins Children's Center scientists has figured out why a respiratory syncytial virus vaccine used in 1966 to inoculate children against the infection instead caused severe respiratory disease and effectively stopped efforts to make a better one.

15 Dec 2008

Mouse model shows blood stem cells in action

Over a period of five years, scientists at the Johannes Gutenberg University Mainz have managed to create a genetically modified mouse in which the activity of the blood stem cells can be tracked.

15 Dec 2008

Fatherhood gene determines if it's a boy or a girl

According to recent research whether men are likely to father a boy or a girl is determined by a "fatherhood gene".

15 Dec 2008

Sarcasm - a diagnostic tool for dementia

Scientists say sarcasm, sometimes referred to as the lowest form of wit, might be a useful tool in diagnosing a certain type of dementia.

15 Dec 2008

Carbon monoxide used to protect mouse nerve cells from damage

Researchers at Johns Hopkins have shown that brain damage was reduced by as much as 62.2 percent in mice who inhale low amounts of carbon monoxide after an induced stroke.

15 Dec 2008

Lung cancer screening feasibility study funded

A study to assess the feasibility of undertaking a UK-based screening trial for lung cancer has been commissioned by the National institute for Health Research Health Technology Assessment (NIHR HTA) programme. Lung cancer kills more people worldwide than any other malignancy accounting for around 1.4 million deaths each year, and around 38,000 individuals are diagnosed with the disease in the UK each year.

15 Dec 2008

Later school start times may improve sleep in teens and decrease risk of auto accidents

Research in the current issue of the Journal of Clinical Sleep Medicine shows that after a one-hour delay of school start times, teens increased their average nightly hours of sleep and decreased their "catch-up sleep" on the weekends, and they were involved in fewer auto accidents.

15 Dec 2008

Continuous positive airway pressure improves sleeping glucose levels in type 2 diabetics with obstructive sleep apnea

A study in the Dec. 15 issue of the Journal of Clinical Sleep Medicine suggests that screening type 2 diabetes patients for obstructive sleep apnea (OSA) and treating those who have OSA with continuous positive airway pressure (CPAP) therapy could improve the management of their hyperglycemia and might favorably influence their long-term prognosis.

15 Dec 2008