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Type 1 diabetes triggered by lazy T-cells

A research team led by Dr. Ciriaco A. Piccirillo of McGill University's Department of Microbiology and Immunology has discovered that in some individuals, the specialized immunoregulatory T-cells that regulate the body's autoimmune reactions may lose their effectiveness and become "lazy" over time, leading to the onset of type 1 diabetes.

16 Jan 2008

Molecules might identify high-risk acute-leukemia patients

New research suggests that certain small molecules used by cells to control the proteins they make might also help doctors identify adult acute-leukemia patients who are likely to respond poorly to therapy.

16 Jan 2008

Gender differences in liver cancer

A fundamental difference in the way males and females respond to chronic liver disease at the genetic level helps explain why men are more prone to liver cancer, according to MIT researchers.

16 Jan 2008

Iowa State researchers aim to improve vaccine technology

A team of Iowa State University researchers is examining a new vaccine method that may change the way we get vaccinations.

16 Jan 2008

Genetic differences may explain response to multiple sclerosis treatment

By comparing the DNA of patients with multiple sclerosis whose symptoms are reduced by interferon beta therapy to the DNA of those who continue to experience relapses, researchers may have identified important genetic differences between the two, according to an article posted online that will appear in the March 2008 print issue of Archives of Neurology.

16 Jan 2008

Unique role of apoptosis protein TRADD in viral signaling

Epstein-Barr virus is incredibly common in humans; up to 95% of adults in the developed world have been infected, which causes glandular fever and has been linked to the development of several forms of cancer.

16 Jan 2008

Researchers find cell protein that blocks HIV virus generation

UCLA researchers have found that a key protein in the body's dendritic cells can stop the virus that causes AIDS from "budding" part of the virus' life cycle that is crucial to its ability to replicate and infect other cells.

16 Jan 2008

Probiotic drinks work - but who knows how or why?

New research from Imperial College London and the Nestlé Research Center, Lausanne, Switzerland, says that probiotic drinks and yoghurts help the gut but it is unclear how or why.

16 Jan 2008

How exactly does aging affect judgment and decision-making abilities?

We often read or hear stories about older adults being conned out of their life savings, but are older individuals really more susceptible to fraud than younger adults?

15 Jan 2008

Researchers find new way to block destructive rush of immune cells

Researchers have found a way to selectively block the ability of white blood cells to "crawl" toward the sites of injury and infection when such mobility drives disease, according to a study published today in The Journal of Experimental Medicine.

15 Jan 2008

New auditory cortex research may bring better hearing aids and more effective speech recognition systems

Recognising people, objects or animals by the sound they make is an important survival skill and something most of us take for granted.

15 Jan 2008

Genetic differences may help explain response to multiple sclerosis treatment

15 Jan 2008

6,000 genes help determine body weight

Reporting in the online journal BMC Genetics, researchers from the Monell Center have for the first time attempted to count the number of genes that contribute to obesity and body weight.

15 Jan 2008

Brain processes aggression as a reward

New research from Vanderbilt University shows for the first time that the brain processes aggression as a reward - much like sex, food and drugs - offering insights into our propensity to fight and our fascination with violent sports like boxing and football.

15 Jan 2008

Uncovering the Achilles' heel of the HIV-1 envelope

New structural details illustrate how a promising class of antibodies may block human immunodeficiency virus (HIV)-1 infection and reveal valuable clues for design of an effective HIV-1 vaccine.

15 Jan 2008

University of Minnesota researchers have created a beating heart in the laboratory

By using a process called whole organ decellularization, scientists from the University of Minnesota Center for Cardiovascular Repair grew functioning heart tissue by taking dead rat and pig hearts and reseeding them with a mixture of live cells. The research will be published online in the January 13 issue of Nature Medicine.

15 Jan 2008

Stem cells make bone marrow cancer resistant to treatment

Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments.

15 Jan 2008

Researchers associate six new genetic variants with heart disease risk factor

Using new techniques for rapidly scanning the human genome, researchers have associated levels of cholesterol and triglycerides, two fats in the blood, to 18 genetic variants, six of which represent new DNA regions never before associated with the traits.

15 Jan 2008