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Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease

Researchers investigating anecdotal evidence that cannabis relieves some of the symptoms of inflammatory bowel disease (IBD) have discovered a potential new target for cannabis-derived drugs for treatment of the disease.

2 Aug 2005

Aging profile of the human brain differs greatly from that seen in chimpanzees

Researchers have found that the two primary areas of the human brain appear to age in radically different ways: The cortex used in higher-level thought undergoes more extensive changes with age than the cerebellum, which regulates basic processes such as heartbeat, breathing and balance.

2 Aug 2005

Drugs with similar chemical attributes as Ecstasy might offer useful alternatives to current therapies for Parkinson's disease

Amphetamines, including the drug popularly known as Ecstasy, can reverse the symptoms of Parkinson's disease in mice with an acute form of the condition, according to new research at Duke University Medical Center.

2 Aug 2005

Protein called cyclin D1 disrupts BRCA1's normal role as a cancer inhibitor

For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases are linked to genetic miscues, about half of which are linked to BRCA1.

2 Aug 2005

Aging and gene expression in the primate brain

While medical science and a healthy lifestyle can help increase life expectancy, many aspects of aging and longevity are beyond our control. Published this week in the open-access journal PLoS Biology, Michael Eisen and colleagues shed light on these genetic factors by identifying sets of genes whose expression changes with age in human and chimp brains.

2 Aug 2005

Arf gene prevents excessive growth of blood vessels in the developing eye

A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital.

2 Aug 2005

Researchers characterize the proteome of the human cornea

In doing so, they have identified 141 distinct proteins, 99 of which had not been previously recognized in mammalian corneas. The details of their findings appear in the August/September issue of Molecular and Cellular Proteomics, an American Society for Biochemistry and Molecular Biology journal.

1 Aug 2005

Discovery that oxidative stress from pollen is as important as antigen exposure could lead to new therapies

For a person with allergies or asthma, breathing in pollen can be a very bad thing. Within minutes of inhalation by someone sensitive to their effects, these tiny particles can trigger severe inflammation of the respiratory passages, producing uncontrollable sneezing, coughing, or extreme shortness of breath -- symptoms agonizingly familiar to those who suffer from allergy and asthma attacks.

1 Aug 2005

Researchers unravel control of growing blood vessels

Researchers at UT Southwestern Medical Center have discovered a basic mechanism by which smooth muscle cells that line the blood vessels can grow - sometimes abnormally - suggesting methods of treatment for various coronary diseases.

1 Aug 2005

Researchers have identified a pathway that is specific for cancer

When cancer spreads, people often die. That's why a lot of cancer research and drugs focus on the metabolic pathways that allow cancer to metastasize -- to spread from one part of the body to another.

1 Aug 2005

Inhibitors of cellular enzymes could be developed for SARS treatment

Researchers from the University of Pennsylvania School of Medicine have found that inhibitors of an enzyme called cathepsin L prevent the SARS (severe acute respiratory syndrome) virus from entering target cells. SARS is caused by an emergent coronavirus. There is no effective treatment at this time.

1 Aug 2005

Brain may interpret the information it receives from sensory neurons using a code more complicated than scientists previously thought

...according to new research from the National Autonomous University of Mexico and Cold Spring Harbor Laboratory. By studying how monkeys perceive a vibrating object when it touches the skin, scientists found that changes in an animal's attention over time influence how a sensory signal is interpreted.

1 Aug 2005

Cannabis drugs may benefit those with bowel disease

UK scientists say they believe that patients with inflammatory bowel disease may benefit from cannabis-based drugs.

1 Aug 2005

Link between peritoneum closure and fewer adhesions

A controversial surgical procedure that has lost favor among medical professionals may benefit women who have had caesarean sections. So say researchers at the Stanford University School of Medicine, who have found that closing the parietal peritoneum, a multi-layered membrane that lines the abdomino-pelvic walls, substantially decreases the likelihood of scarring that can make future C-sections more difficult.

1 Aug 2005

Controlling the expression of genes by turning them on or off could produce a drug for the treatment or cure of almost any disease

A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center.

1 Aug 2005

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Professor Susan Wray, who heads the UK's top rated Department of Physiology, and Dr. Ted Burdyga, are studying muscles in the wall of the ureter, which connects the kidney to the bladder, to understand how muscles respond to signals in the body telling them to contract or relax.

1 Aug 2005

Pseudomonas aeruginosa has broken the immune system's code

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

1 Aug 2005

Medical Research News

Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease

Aging profile of the human brain differs greatly from that seen in chimpanzees

Drugs with similar chemical attributes as Ecstasy might offer useful alternatives to current therapies for Parkinson's disease

Protein called cyclin D1 disrupts BRCA1's normal role as a cancer inhibitor

Aging and gene expression in the primate brain

Arf gene prevents excessive growth of blood vessels in the developing eye

Researchers characterize the proteome of the human cornea

Discovery that oxidative stress from pollen is as important as antigen exposure could lead to new therapies

Researchers unravel control of growing blood vessels

Researchers have identified a pathway that is specific for cancer

Inhibitors of cellular enzymes could be developed for SARS treatment

Brain may interpret the information it receives from sensory neurons using a code more complicated than scientists previously thought

Cannabis drugs may benefit those with bowel disease

Link between peritoneum closure and fewer adhesions

Controlling the expression of genes by turning them on or off could produce a drug for the treatment or cure of almost any disease

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Pseudomonas aeruginosa has broken the immune system's code

People can show early warning signs of Alzheimer's disease years before they are officially diagnosed

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

Good bacteria helps ease symptoms of ulcerative colitis

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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