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New use for a cell toxin found to inhibit survival proteins in cancer cells

A chemically-modified version of a mitochondrial toxin long used to control species of invasive fish in lakes has been found to selectively inhibit two "survival proteins" in cancer cells.

11 Jul 2007

Cancer-causing enzyme could be stopped

Scientists from the MRC's Laboratory of Molecular Biology (LMB) and the Albert Einstein College of Medicine have discovered a way to stop an enzyme responsible for many cancers.

11 Jul 2007

Diabetes researcher honored with prestigious Novartis prize

John E. Gerich, M.D., professor of Medicine and program director of the General Clinical Research Center at the University of Rochester Medical Center, has been awarded the Novartis Prize for Long-Standing Achievement in Diabetes.

11 Jul 2007

White blood cells are picky about sugar

Biology textbooks are blunt - neutrophils are mindless killers. These white blood cells patrol the body and guard against infection by bacteria and fungi, identifying and destroying any invaders that cross their path. But new evidence, which may lead to better drugs to fight deadly pathogens, indicates that neutrophils might actually distinguish among their targets.

11 Jul 2007

Obesity rate in the U.S. has increased at an alarming rate over the past three decades

The U.S. obesity prevalence increased from 13 percent to 32 percent between the 1960s and 2004, according to researchers at the Johns Hopkins Bloomberg School of Public Health Center for Human Nutrition.

11 Jul 2007

Researchers measure effect of hepatitis B on patients' quality of life

"Am I going to die? I have no future." "I feel depressed at times, fearful I may not see my children marry or be a grandparent." Such heart-rending statements from patients with chronic hepatitis B reveal the social and mental impact of this disease, which affects 350 million worldwide.

11 Jul 2007

Master switch for the production of brown fat discovered

Researchers at Dana-Farber Cancer Institute have identified a long-sought "master switch" in mice for the production of brown fat, a type of adipose tissue that generates heat and counters obesity caused by overeating.

11 Jul 2007

Neural stem cells for Parkinson's disease

A University of South Florida neuroscientist reports that the cutting-edge research study of human stem cells in primates with Parkinson's disease is compelling on several fronts , particularly how the transplanted cells did their job of easing disease symptoms.

11 Jul 2007

Magnetic resonance spectroscopy for breast cancer

The American Cancer Society recently issued new recommendations for women with a higher risk of developing breast cancer, including those with a family history of breast or ovarian cancer, and those who may carry genetic mutations (BRCA1 or BRCA2) that make them more likely to develop the disease.

11 Jul 2007

Genetically engineered herpes simplex virus keeps arteries free-flowing

A genetically engineered herpes simplex virus, primarily known for causing cold sores, may help keep arteries "free-flowing" in the weeks following angioplasty or stent placement for patients, according to research published early in the online edition of PNAS (Proceedings of the National Academy of Sciences of the United States of America).

11 Jul 2007

Potential role of milk thistle as an anticancer agent

Milk thistle extract, an herbal remedy since the times of the ancient Greeks and Romans, is today one of the most popular herbal supplements, with U.S. retail sales of nearly nine million dollars.

11 Jul 2007

Cicardian system suffers and protects from prenatal cocaine exposure

Researchers from Boston University School of Medicine (BUSM) have shown that prenatal cocaine exposure in zebrafish (which share the majority of the same genes with humans) can alter neuronal development and acutely dysregulate the expression of circadian genes and those affecting melatonin signaling, growth and neurotransmission.

11 Jul 2007

Discovery of gallstone gene

Scientists at the University of Bonn, together with colleagues from Romania, have discovered a gene variant that significantly increases the risk of developing gallstones (Hepatology No. 46, 11 July 2007, DOI 10.1002/hep.21847).

11 Jul 2007

First-time link between food intolerance and illness

Researchers from University College London have found compelling evidence for the first time to link food intolerances and serious illness.

11 Jul 2007

How immune cells catch pathogens

To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalise and destroy them.

11 Jul 2007

Top brain experts say alcohol does not destroy brain cells

At an international neural stem cell conference in Australia, ninety of the world's top scientists in neural stem cell and brain development research, from 11 different countries were brought together last month by the Queensland Brain Institute (QBI).

11 Jul 2007

Antibiotics for children with urinary tract infections create even more problems

New research has questioned the use of antibiotics for children with urinary tract infections.

11 Jul 2007

Uncooked fish linked with liver cancer in Asia

An age old preference for eating uncooked fish dishes like koi-pla puts people in SE Asia at risk of ingesting trematodes that can cause a type of liver cancer called cholangiocarcinoma (cancer of the bile ducts), say researchers in this week's PLoS Medicine.

10 Jul 2007

No compelling evidence that meditation has therapeutic value

While it's not likely to do you any harm, there is also no compelling evidence that meditation has therapeutic value, says a new report from the University of Alberta.

10 Jul 2007

Scientists identify two brain networks in Parkinson's

The disease that causes tremors, rigidity and slowed movements in a million Americans also targets another brain network that regulates cognitive thought and the ability to carry out everyday tasks.

10 Jul 2007