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Muscle restoration in an animal model of Duchenne muscular dystrophy

Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of Duchenne's muscular dystrophy (DMD).

24 Apr 2007

Miscue of body's genetic repair system may cause Huntington's disease

Mayo Clinic researchers, along with collaborators from the National Institutes of Health (NIH) and University of Oslo, Norway, have discovered that a miscue of the body's genetic repair system may cause Huntington's disease, a fatal condition that affects 30,000 Americans annually by destroying their nervous system.

24 Apr 2007

Chitin compound causes allergic inflammation

The beetle's back and the crab's shell owe their toughness to a common compound called chitin that now appears to trigger airway inflammation and possibly asthma, UCSF scientists have found.

24 Apr 2007

Johns Hopkins creates database of phosphorylation events

Researchers at Johns Hopkins took advantage of a new technique that reads the makeup of proteins to identify nearly all chemical changes nature makes by adding phosphate to proteins manufactured in human cells.

24 Apr 2007

UNC-45 protein critical to proper formation of muscles

Proper formation of the proteins that power heart and skeletal muscle seems to rely on a precise concentration of a "chaperone" protein known as UNC-45, according to a new study.

24 Apr 2007

NYU Medical Center partners with Rosetta Genomics to tackle mesothelioma

Rosetta Genomics, Ltd has announced that it has partnered with NYU Medical Center with the aim of developing a line of early detection diagnostic products for lung, and Mesothelioma cancers.

24 Apr 2007

Discovery of new genes associated with fever-related seizures that occur in infancy and childhood

Researchers have localized two new genes that are associated with fever-related seizures that occur in infancy and childhood, according to a study published in the April 24, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.

24 Apr 2007

Stoichiometric controls of mercury dilution by growth

Research led by Dartmouth scientists found that animals fed nutritious, high-quality food end up with much lower concentrations of toxic methylmercury in their tissues.

24 Apr 2007

Low vitamin D levels linked to poor physical performance in older adults

Older adults who don't get enough vitamin D - either from their diets or exposure to the sun - may be at increased risk for poor physical performance and disability, according to new research from Wake Forest University School of Medicine and colleagues.

24 Apr 2007

Junk DNA plays a role in controlling when genes turn on and off

Large swaths of garbled human DNA once dismissed as junk appear to contain some valuable sections, according to a new study by researchers at the Stanford University School of Medicine and the University of California-Santa Cruz.

24 Apr 2007

New methods for treating lung cancer cells that have become resistant to new anti-cancer agents

Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center have developed methods for treating lung cancer cells that have become resistant to new anti-cancer agents.

24 Apr 2007

Inflammatory bowel disease linked to nerve damage and other neurological problems

People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 , May 5, 2007.

24 Apr 2007

GP surgeries with specialist nurses can help save lives

One of the biggest research trials carried out in GP surgeries has confirmed that those with specialist cardiac nurse clinics can help to improve patients' lives.

24 Apr 2007

Exercise reduces risk for Parkinson's disease

The risk of developing Parkinson's disease may be reduced with moderate to vigorous exercise or other recreational activities, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 , May 5, 2007.

24 Apr 2007

Eating regularly in some fast-food restaurants unsafe

Eating regularly in some fast-food chain outlets is unsafe in many parts of the world, top Danish research experts warn today.

24 Apr 2007

Potential therapeutic target for multiple sclerosis

Oregon Health & Science University neuroscientists are eyeing a protein as a potential therapeutic target for multiple sclerosis because de-activating it protects nerve fibers from damage.

24 Apr 2007

New direction for therapies to treat amyotrophic lateral sclerosis

Researchers from The Ludwig Institute and the University of California, San Diego (UCSD) School of Medicine have discovered that when motor neurons damaged by amyotrophic lateral sclerosis (ALS), or Lou Gehrig?s disease, inappropriately send the wrong signal, immune cells react by killing the messenger.

24 Apr 2007

Qigong helped people during SARS outbreak

Oriental therapies can help chronically ill people stay strong and reduce stress levels during epidemics, according to research in the April issue of the UK-based Journal of Clinical Nursing.

24 Apr 2007

Naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells

These findings, which were published online March 20 in the Journal of Biological Chemistry and will be in press on May 4, offer hope for a more selective, less toxic therapy for leukemia.

24 Apr 2007

Klotho proteins important players in future therapies for diabetes, obesity and kidney disease

A relative of the anti-aging gene Klotho helps activate a hormone that can lower blood glucose levels in fat cells of mice, making it a novel target for developing drugs to treat human obesity and diabetes, UT Southwestern Medical Center researchers have found.

24 Apr 2007