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Gene mutation associated with deafness can play an important part in wound healing

A mutation in a gene commonly associated with deafness can play an important part in improving wound healing, a scientist told the annual conference of the European Society of Human Genetics in Amsterdam, The Netherlands.

8 May 2006

A pericellular collagenase directs the 3-D development of white adipose tissue

In the journal Cell, researchers report the serendipitous discovery that the initial development of fat requires a "remodeling" protein that must first make way for the lipid-laden tissue's growth.

8 May 2006

Discovery of gene that appears to play an important role in the onset of type 2 diabetes

In a painstaking set of experiments in overweight mice, scientists from the University of Wisconsin-Madison have discovered a gene that appears to play an important role in the onset of type 2 diabetes.

8 May 2006

Bacterial binding in the stomach

Scientists have determined that decay-accelerating factor (DAF), a protein found in epithelial cells in the stomach, acts as a receptor for the bacteria Helicobacter pylori. Blocking this interaction could lead to new drugs that reduce the risk of peptic ulcer disease or gastric cancer.

8 May 2006

Important insights into how cells regulate certain growth-proteins

Researchers here have discovered a new mechanism used by cells - and manipulated by retroviruses - to control the making of certain essential proteins, including some involved in cancer.

8 May 2006

Research into tiny muscle movements proves useful in anti-terror investigations

When trying to lie your way through any situation, keep a tight rein on your zygo maticus major and your orbicularis oculi. They'll give you away faster than a snitch.

8 May 2006

Mutated gene leads to JSRD

The research team, directed by Joseph Gleeson, M.D., Director of the Neurogenetics Laboratory at the UCSD School of Medicine and associate professor in the Department of Neurosciences, have identified a new gene that, when mutated, leads to JSRD. Their findings will be published on-line in advance of publication in the journal Nature Genetics.

8 May 2006

Researchers have made important progress in regenerating hearing cells

Massachusetts General Hospital (MGH) researchers have made important progress in their ongoing effort to regenerate the inner ear's hair cells, which convert sound vibrations to nerve impulses.

3 May 2006

Pten regulates neuronal arborization and social interaction in mice

While the causes of autism remain complex and mysterious, researchers are steadily adding pieces to its intricate puzzle. In what they believe to be a significant new approach to understanding "autism spectrum disorders" (ASD), researchers have developed a mouse that shows abnormal social interactions and brain hypertrophy characteristic of the disease.

3 May 2006

New technique for freezing and preserving genetically enhanced pig embryos

Researchers led by a University of Missouri-Columbia professor of reproductive biotechnology have reported success in freezing and preserving swine embryos that were created by in vitro techniques and that carried modified genetic material.

3 May 2006

Researchers pinpoint autism's genetic roots

By deleting a gene in certain parts of the brain, researchers at UT Southwestern Medical Center have created mice that show deficits in social interaction that are reminiscent of humans with autism spectrum disorders.

3 May 2006

Combination of genetic mutation and viral infection may cause prostate cancer

Significant recent interest in the literature (JAMA 2006;295:1503, Lancet, epub) and by patients has arisen in response to a presentation given by Dr. Eric Klein of the Cleveland Clinic at the 2006 Prostate Cancer Symposium in San Francisco, February 24, 2006.

3 May 2006

Inhibiting cell process may give cancer drug a boost

A molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug, according to findings appearing in the May 3 issue of the European Journal of Cancer.

3 May 2006

Brain scan could reveal who will get Alzheimer's disease

According to researchers in California, a brain scan may possibly identify structural and metabolic brain changes that predict dementia or cognitive decline in normal older adults.

3 May 2006

Melatonin, taken orally can improve ability to sleep

Researchers from the Divisions of Sleep Medicine at Brigham and Women's Hospital and Harvard Medical School have found in a double-blind placebo-controlled clinical study, that melatonin, taken orally during non-typical sleep times, significantly improves an individual's ability to sleep.

3 May 2006

Death risks high in younger people with diabetes

People with Type 2 diabetes aged between 35 and 54 are over three times more likely to die than those without the condition according to research published in the journal Diabetic Medicine.

3 May 2006

DARPA grant supports research toward realizing tissue regeneration

While U.S. soldiers fighting in Iraq and Afghanistan are surviving injuries that in previous conflicts likely would have been fatal, the number of wounded with major tissue loss has never before been so high.

3 May 2006

Differential effects of HOXB4 on nonhuman primate short and long-term repopulating cells

Transplantation of hematopoietic stem cells (HSCs, the cells that can give rise to all blood and most immune cell types) can save patients whose own hematopoietic system is defective or has been destroyed (often through radiation or chemotherapy of cancer).

3 May 2006

Endocannabinoid system shows promise in combating obesity

As the obesity epidemic grows in the United States, the medical community is faced with the significant challenge of properly treating patients before complications such as heart disease arise.

3 May 2006