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Soft tumor environments prime cancer cells for survival during metastasis

Researchers have discovered how the mechanical properties of tumors can prime cancer cells to better survive their spread to other organs.

13 Apr 2024

Study finds dysfunction of key brain systems in people with psychosis

Inside the brains of people with psychosis, two key systems are malfunctioning: a "filter" that directs attention toward important external events and internal thoughts, and a "predictor" composed of pathways that anticipate rewards.

13 Apr 2024

Addressing public health challenges through behavioral interventions

The concept of "One Health" – which emphasizes the relationship between human, animal, plant and environmental health – has been gaining ground in scientific discussions in recent years.

13 Apr 2024

Childhood verbal abuse costs global society $300 billion annually, study finds

Childhood verbal abuse by adults costs society an estimated $300 billion (£239 billion) a year globally, show findings presented at the first international conference on childhood verbal abuse, hosted by UCL, Words Matter and the World Health Organization (WHO).

13 Apr 2024

Neural circuitry in the spinal cord allows brain-independent motor learning

Aya Takeoka at the RIKEN Center for Brain Science (CBS) in Japan and colleagues have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning.

13 Apr 2024

Women predominantly treated for anxiety and depression at psychiatric outpatient clinics

More than 75% of the patients treated at the psychiatric outpatient clinic of Hospital de Base in São José do Rio Preto, São Paulo state (Brazil), are women with a mean age of 45 and suffering from sadness, anxiety and irritability, according to a study reported in the journal Frontiers in Psychiatry.

13 Apr 2024

Study reveals metabolic markers linked to long COVID-19 severity

Long COVID-19, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a global health phenomenon characterized by persistent symptoms following the acute phase of COVID-19.

13 Apr 2024

Intraoperative anemia linked to higher female mortality after heart bypass surgery

Women are at higher risk of death when undergoing heart bypass surgery than men. Researchers at Weill Cornell Medicine have determined that this disparity is mediated, to a large extent, by intraoperative anemia - the loss of red blood cells during surgery.

13 Apr 2024

New murine model sheds light on anti-MDA5 antibody-positive dermatomyositis

Some diseases involve autoimmune reactions, when the body begins to attack its own cells and proteins.

13 Apr 2024

Hypertensive disorders in pregnancy strongly associated with cardiovascular mortality after giving birth

Rutgers Health researchers have found that hypertensive disorders in pregnancy are strongly associated with fatal cardiovascular disease for up to a year after birth.

13 Apr 2024

Research sheds light on post-sepsis immune suppression mechanism

Severe sepsis from bacterial or viral infections can be life-threatening and even people recovering from severe sepsis may experience long-lasting effects on the immune system, making them more susceptible to recurrent infections.

13 Apr 2024

Unraveling the mysteries of gastro-esophageal junction development

The transition from the esophagus to the stomach is a delicate region from a medical point of view, often associated with pathological disorders leading to cancer.

13 Apr 2024

Mayo Clinic study offers insights into lucid episodes in dementia

A recent Mayo Clinic study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association investigated lucid episodes in people living with later stages of dementia, providing insights into how these occurrences reveal themselves.

13 Apr 2024

ERC Advanced grant awarded to crack the code of cartilage repair

In our aging society, healing joint problems is becoming increasingly important. To do this, cartilage damage must become repairable.

12 Apr 2024

Study aims to explore the underlying causes of excessive alcohol production in overweight people

The microorganisms in the intestines of many overweight people produce alcohol to an increased extent, as Max Nieuwdorp, professor of Internal Medicine at Amsterdam UMC discovered a few years ago.

12 Apr 2024

AI model can accurately screen for post-traumatic stress disorder after childbirth

A generative artificial intelligence (AI) model that can analyze the narrative accounts of women who have undergone recent childbirth has shown the ability to accurately screen for post-traumatic stress disorder (CB-PTSD), a study by Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system has found.

12 Apr 2024

Cystic fibrosis drug found to be safe and effective in newborns

A Cystic Fibrosis drug targeting the basic defect that causes the condition has been shown to be safe and effective in newborns aged four weeks and above, new research involving RCSI University of Medicine and Health Sciences and Children's Health Ireland has found.

12 Apr 2024

Hospital sinks fuel antibiotic-resistant bacteria spread

A new study published today in the American Journal of Infection Control reports the infection prevention steps taken to control a months-long multispecies outbreak of carbapenemase-producing Enterobacterales that occurred in a pediatric ward at the Toho University Omori Medical Center in Tokyo in 2017.

12 Apr 2024

Hypoglossal nerve stimulation offers hope for pediatric Down syndrome patients with OSA

While Obstructive Sleep Apnea (OSA) affects about five percent of the general pediatric population, 80 percent of children with Down syndrome experience OSA. Continual OSA results in poor health, including disruptions to cognitive development and functioning, leading physician-researchers from Mass General Brigham to investigate better methods to treat these patients as early as possible to maximize their health outcomes.

12 Apr 2024