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Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and delayed growth or puberty.

18 Feb 2022

The ability of therapeutic monoclonal antibodies to neutralize SARS-CoV-2 Omicron BA.2 variant

Researchers evaluated the neutralizing capacity of the clinically approved mAbs against the SARS-CoV-2 Omicron BA.2 variant.

18 Feb 2022

International Aspirin Foundation publishes a report on the work of highly commended investigators

The International Aspirin Foundation has published a report of the Winner and Highly Commended awardees, present at the prestigious Emerging Aspirin Investigator Award Ceremony.

18 Feb 2022

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Researchers conducted a retrospective cohort study to assess the rate of SARS-CoV-2 reinfection in patients who had recovered from COVID-19.

18 Feb 2022

Meta-analysis of population-based seroprevalence studies to estimate SARS-CoV-2 seroprevalence in Africa

Researchers conducted a descriptive meta-analysis to estimate the seroprevalence of SARS-CoV-2 infections in Africa.

18 Feb 2022

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

A recent study explored the safety, immunogenicity, and VE of the SARS-CoV-2 mRNA BNT162b2 and mRNA1273 vaccines against its Omicron VOC in HCWs in Israel.

18 Feb 2022

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Researchers have been examining the pathology and spread of the Omicron variant in mink.

18 Feb 2022

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

A new study aimed to clarify whether extensive RBD mutations could affect the magnitude and immunodominance hierarchy of the host antibody response.

18 Feb 2022

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Melanoma, a type of skin cancer, is often curable when detected and treated in its early stages. However, the disease can rapidly spread to other organs in the body and become deadly. According to the American Cancer Society, more than 7,600 people die of the disease each year in the United States.

17 Feb 2022

Intermediate size nanoparticles may be effective at stopping internal bleeding

Traumatic injuries are the leading cause of death in the U.S. among people 45 and under, and such injuries account for more than 3 million deaths per year worldwide.

17 Feb 2022

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

Researchers assess how fast the SARS-CoV-2 Alpha and Delta variants transmit from transmission data in a household study.

17 Feb 2022

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML) that may define a new subtype of the disease.

17 Feb 2022

Messenger RNA can be used at low doses to regenerate bone without side effects

Although fractures normally heal, bone will not regenerate under several circumstances. When bone does not regenerate, major clinical problems could result, including amputation.

17 Feb 2022

New high-risk subtype of relapsed pediatric AML revealed

When acute myeloid leukemia (AML) relapses, it is more difficult to treat and outcomes are dismal. Scientists at St. Jude Children's Research Hospital have discovered a mutation in pediatric AML that physicians can use to identify high-risk patients and better guide treatment.

17 Feb 2022

Older adults can prevent memory decline by sticking to regular exercise

We all know exercise is good for us, but that still leaves plenty of questions. How much exercise? Who benefits the most? And when in our lives? New research led by University of Pittsburgh psychologists pools data from dozens of studies to answer these questions, showing that older adults may be able to prevent declines in a certain kind of memory by sticking to regular exercise.

17 Feb 2022

Study reveals mechanisms associated with severe blood clotting in COVID-19 patients

After studying blood samples from 244 patients hospitalized for COVID-19, a group of researchers, including those who work at the National Institutes of Health, identified “rogue antibodies” that correlate with severe illness and may help explain mechanisms associated with severe blood clotting.

17 Feb 2022

Medical Science News

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

The ability of therapeutic monoclonal antibodies to neutralize SARS-CoV-2 Omicron BA.2 variant

International Aspirin Foundation publishes a report on the work of highly commended investigators

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Meta-analysis of population-based seroprevalence studies to estimate SARS-CoV-2 seroprevalence in Africa

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Intermediate size nanoparticles may be effective at stopping internal bleeding

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

New mutation may define a high-risk subtype of pediatric acute myeloid leukemia

Messenger RNA can be used at low doses to regenerate bone without side effects

New high-risk subtype of relapsed pediatric AML revealed

Older adults can prevent memory decline by sticking to regular exercise

Study reveals mechanisms associated with severe blood clotting in COVID-19 patients

Data management challenges in scientific research

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

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