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Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

In a new study, researchers evaluated SARS-CoV-2 vaccination-induced T cell responses cross-recognition among the early and novel SARS-CoV-2 variants.

26 Jan 2022

Study suggests synthetic SARS-CoV-2 S glycoprotein coated lipid vesicles are an effective vaccine candidate

In a new study, a team of researchers developed a vaccine candidate with the SARS-CoV-2 spike (S) glycoprotein coated onto lipid vesicles which resembles virus-like particles.

26 Jan 2022

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

An interdisciplinary team of researchers from Europe analyzed the alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients.

26 Jan 2022

Does remdesivir reduce mortality in moderately ill hospitalized patients with COVID-19?

A team of researchers performed a meta-analysis to investigate the use of remdesivir in the treatment of COVID-19.

26 Jan 2022

Exploring hematological alterations in COVID-19 patients

New study findings indicated that some hematological alterations that occur during COVID-19-related hospital admission were associated with an increase in the risk of COVID-19-associated ICU admission and mortality.

26 Jan 2022

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

A study recently identified Neurolipin-1 or NRP1, a host factor for SARS-CoV-2 infection, as a cargo retrograde-transported by the ESCPE-1.

26 Jan 2022

Study demonstrates differential alternative splicing in betacoronaviruses

A new study investigates whether the proportion of ribosomal genes displaying differential gene expression and differential alternative splicing differed between three betacoronaviruses and six other viruses and bacteria.

26 Jan 2022

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

In a recent study, whole mRNA-seq was used to investigate the global effects of SARS-CoV-2 viral genes Nsp6, Nsp8, and M on the transcriptome of hPSC-CMs.

26 Jan 2022

The new Omicron subvariant BA.2: what we know so far

Presently, an Omicron subvariant known as BA.2, first identified in late 2021, has made headlines due to its rapid spread.

26 Jan 2022

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

In a new study, scientists have compared the Omicron variant with the Delta VOC (B.1.617.2) as well as the wildtype strain (B.1), with respect to their interaction with the antiviral type 1 interferon response in infected cells.

26 Jan 2022

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

A recent study analyzed the effects of the interaction between SARS-CoV-2 Omicron spike amino acid and the human ACE2 receptor or with human antibodies.

26 Jan 2022

Anti-SARS-CoV-2 antibodies found in wild mustelids in France

A new study focused on the identification of SARS-CoV-2 infection in wild mustelids in the French region of Brittany.

26 Jan 2022

Evaluating the use of megadoses of corticosteroids as a treatment of COVID-19

In a new study, researchers have been investigating the effects of megadoses of corticosteroids on hospitalized COVID-19 patients.

26 Jan 2022

DoD Awards Contract to Siemens Healthineers to Purchase COVID-19 Antigen Over-the-Counter Test Kits in Support of POTUS' 500 Million Free At-Home COVID-19 Tests

On Jan. 21, 2022, the Department of Defense (DoD) awarded a contract to Siemens Healthineers to procure 50 million over-the-counter COVID-19 test kits.

From Siemens Healthineers 26 Jan 2022

Test-negative case-control analysis during a Delta variant-dominant period in California’s prisons

A new study studies the waning of vaccine-conferred protection against SARS-CoV-2 infection, specifically the Delta variant, in two high-risk populations.

26 Jan 2022

Research says spill-over of SARS-CoV-2 from humans to cattle is possible

In a recent study posted to the bioRxiv* preprint server, a team of researchers assessed the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from humans to cattle.

26 Jan 2022

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

26 Jan 2022

SARS-CoV-2 infection found in wild white-tailed deer in Canada

In a recent study posted to the bioRxiv* preprint server, scientists investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in white-tailed deer (WTD) in southern Québec, Canada, as part of a more extensive pan-Canadian analysis into SARS-CoV-2 spillover into wildlife. To further define SARS-CoV-2 infection in this species, researchers used viral genomes and isolation.

25 Jan 2022

SARS-CoV-2 infection and vaccination-induced T cells cross-recognize Omicron

In a recent study posted to the Nature In Review* preprint server, researchers performed a comprehensive, in-depth comparison of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell epitope repertoire following natural infection of coronavirus disease 2019 (COVID-19) compared to messenger ribonucleic acid (mRNA) vaccinations.

25 Jan 2022

COVID-19 research made easier with outbreak.info

In a recent paper posted to the bioRxiv* preprint server, researchers reveal the development of an open-source database that provides data on coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) resources.

25 Jan 2022

Medical Science News

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

Study suggests synthetic SARS-CoV-2 S glycoprotein coated lipid vesicles are an effective vaccine candidate

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

Does remdesivir reduce mortality in moderately ill hospitalized patients with COVID-19?

Exploring hematological alterations in COVID-19 patients

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

Study demonstrates differential alternative splicing in betacoronaviruses

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

The new Omicron subvariant BA.2: what we know so far

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

Anti-SARS-CoV-2 antibodies found in wild mustelids in France

Evaluating the use of megadoses of corticosteroids as a treatment of COVID-19

DoD Awards Contract to Siemens Healthineers to Purchase COVID-19 Antigen Over-the-Counter Test Kits in Support of POTUS' 500 Million Free At-Home COVID-19 Tests

Test-negative case-control analysis during a Delta variant-dominant period in California’s prisons

Research says spill-over of SARS-CoV-2 from humans to cattle is possible

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

SARS-CoV-2 infection found in wild white-tailed deer in Canada

SARS-CoV-2 infection and vaccination-induced T cells cross-recognize Omicron

COVID-19 research made easier with outbreak.info

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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