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Penn State's neural engineering training program receives support from NIH

Penn State has a new cross-disciplinary program to train graduate students interested in the complex landscape of the human brain, supported by a $1.5 million grant from the National Institutes of Health.

2 Jul 2021

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Methylglyoxal (MG) is a highly reactive α-ketoaldehyde formed endogenously as a byproduct of the glycolytic pathway. MG accumulates under conditions of hyperglycemia, impaired glucose metabolism, or oxidative stress.

2 Jul 2021

Research pinpoints a molecular component responsible for modulating flu damage

New experimental data pinpoints a molecular component responsible for modulating the damage the flu can wreck on the lungs.

2 Jul 2021

Salivary markers of oxidative stress during severe COVID-19

An interesting study from researchers at the University of Sharjah, Sharjah, United Arab Emirates, presents evidence that an elevated level of expression of oxidant molecules may be correlated with severe infection and lung injury.

2 Jul 2021

B cell depleting agents can cause altered immune responses to COVID-19 vaccines, suggests study

A new preprint, available on the medRxiv* server, describes altered responses to the use of the highly effective messenger RNA (mRNA) vaccines from Pfizer/BioNTech and Moderna in patients with multiple sclerosis on anti-CD20 (MS-aCD20) monotherapy.

2 Jul 2021

What role did the SARS-CoV-2 delta variant play in India’s devastating second wave?

A detailed report, available on the preprint server medRxiv*, describes the various facets of the second wave that set it apart from the first. The report also contains the findings of an extended SIR model that explored the potential effects of intervention at various time points in the second wave.

2 Jul 2021

The use of flavonoids as antiviral agents against SARS-CoV-2

Researchers in Iran have undertaken a comprehensive review of flavonoids and their antiviral potential against SARS-CoV-2.

2 Jul 2021

Research highlights long-lasting effects of childhood reading problems on cognitive skills

Reading difficulties in childhood are linked to poorer cognitive skills in older age and a greater likelihood of registering scores indicative of dementia risk, suggests research published online in the Journal of Epidemiology & Community Health.

2 Jul 2021

Replication of SARS-CoV-2 in nasal ciliated cells could provide a new vaccination target

Researchers have found that nasal ciliated cells are targeted at the onset of COVID-19 infection, which may help to establish nasal mucosal immunity.

2 Jul 2021

New immunotherapy treatment for cancer patients is more effective and less dangerous

Cell toxicity during immunotherapy is a major limitation to cancer treatment.

2 Jul 2021

New PET imaging method tracks immunotherapeutic efficacy in mouse models

Several cancer tumors grow through immunosuppression; that is, they manipulate biological systems in their microenvironments and signal to a specific set of immune cells--those that clear out aberrant cells--to stop acting. It is no wonder that immunotherapy designed to re-establish anti-tumor immunity is rapidly becoming the treatment of choice for these cancers.

2 Jul 2021

New technique identifies specific neural pathways involved in executive functions of the brain

The human brain is a wonderfully enigmatic organ, helping to juggle multiple tasks efficiently to help us get through a long day! This feature, called executive function, seats primates like us at the pinnacle of evolution.

2 Jul 2021

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Evidence continues to mount that vaccination against COVID-19, most notably the Pfizer and Moderna vaccines, produces robust, durable protection in the vast majority of recipients.

2 Jul 2021

Immunity to SARS-CoV-2 could last longer than originally believed

One year after infection by SARS-CoV-2, most people maintain anti-Spike antibodies regardless of the severity of their symptoms, according to a study with healthcare workers co-led by the Barcelona Institute for Global Health (ISGlobal), the Catalan Health Institute (ICS) and the Jordi Gol Institute (IDIAP JG), with the collaboration of the Daniel Bravo Andreu Private Foundation.

2 Jul 2021

Is there a link between circadian rhythms and COVID-19 severity?

This study showed that the time of day of SARS-CoV-2 infection could impact the severity of the viral infection and the host immune response.

1 Jul 2021

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

A team of researchers recently demonstrated that mutations in the S protein of SARS-CoV-2 select for amino acid changes that result in a more stable protein than would otherwise be expected.

1 Jul 2021

Mustard seed, wall rocket and turmeric extracts show potential against SARS-CoV-2 in vitro

Researchers in Spain have identified plant extracts that may be of interest in the search for treatments of coronavirus disease 2019 (COVID-19) and serve as a basis for future chemical, in vivo, and clinical trials.

1 Jul 2021

Grapevine leaf extract inhibits SARS-CoV-2 and HSV-1 replication in the lab

Researchers in Italy have shown that leaf extract from the common grapevine – Vitis vinifera – exhibits significant antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

1 Jul 2021

Study finds a neural circuit for spirituality and religiosity

More than 80 percent of people around the world consider themselves to be religious or spiritual. But research on the neuroscience of spirituality and religiosity has been sparse.

1 Jul 2021

Loss of PTHrP hormone can prevent metastases, improve survival in mice with pancreatic cancer

Lowering levels of a hormone called PTHrP can prevent metastases and improve survival in mice with pancreatic cancer and could lead to a new way to treat patients, according to a study from cancer researchers at Columbia University Vagelos College of Physicians and Surgeons and Herbert Irving Comprehensive Cancer Center and with collaborators at the University of Pennsylvania.

1 Jul 2021

Medical Science News

Penn State's neural engineering training program receives support from NIH

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Research pinpoints a molecular component responsible for modulating flu damage

Salivary markers of oxidative stress during severe COVID-19

B cell depleting agents can cause altered immune responses to COVID-19 vaccines, suggests study

What role did the SARS-CoV-2 delta variant play in India’s devastating second wave?

The use of flavonoids as antiviral agents against SARS-CoV-2

Research highlights long-lasting effects of childhood reading problems on cognitive skills

Replication of SARS-CoV-2 in nasal ciliated cells could provide a new vaccination target

New immunotherapy treatment for cancer patients is more effective and less dangerous

New PET imaging method tracks immunotherapeutic efficacy in mouse models

New technique identifies specific neural pathways involved in executive functions of the brain

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Immunity to SARS-CoV-2 could last longer than originally believed

Is there a link between circadian rhythms and COVID-19 severity?

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

Mustard seed, wall rocket and turmeric extracts show potential against SARS-CoV-2 in vitro

Grapevine leaf extract inhibits SARS-CoV-2 and HSV-1 replication in the lab

Study finds a neural circuit for spirituality and religiosity

Loss of PTHrP hormone can prevent metastases, improve survival in mice with pancreatic cancer

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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