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IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.

11 Nov 2020

Researchers identify new prognostic markers for colon cancer

The gut-associated lymphoid tissue represents an integral part of the immune system. Among the powerful players of the mucosa-associated lymphoid tissue are isolated lymphoid structures (ILSs).

11 Nov 2020

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

High doses of vitamin C under study for treating COVID-19 may benefit some populations, but investigators exploring its potential in aging say key factors in effectiveness include levels of the natural transporter needed to get the vitamin inside cells.

11 Nov 2020

Study indicates the role of Polβ enzyme in cognitive development

It's a fact of life that things break down. And when they do, whether it's your car, the roof, or a blocked artery, there are people who we can call to help with the repairs.

11 Nov 2020

Study: Sleep loss hijacks the brain's ability to unlearn fear-related memories

Sleep is crucial for consolidating our memories, and sleep deprivation has long been known to interfere with learning and memory.

11 Nov 2020

Synthetic protein nanoparticle may treat aggressive brain cancer

A new synthetic protein nanoparticle capable of slipping past the nearly impermeable blood-brain barrier in mice could deliver cancer-killing drugs directly to malignant brain tumors, new research from the University of Michigan shows.

11 Nov 2020

Gene signature may help develop new therapies against advanced prostate cancer

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Microglia -- the brain's immune cells -- play a primary role in removing cellular debris from the brain. According to a recent study by a Nagoya University-led research team in Japan, another kind of brain cell, called astrocyte, is also involved in removing debris as a backup to microglia.

11 Nov 2020

Study: SphK2 enzyme regulates immune cell responses during viral infection

Viruses such as HIV, hepatitis B and hepatitis C evade or disrupt the immune system to create persistent infections.

11 Nov 2020

“Molecular volume knob” in the brain helps with learning, memory

A "molecular volume knob" regulating electrical signals in the brain helps with learning and memory, according to a Dartmouth study.

11 Nov 2020

Optical technique could transform accuracy and detection of biomechanical alterations of cells

Scientists have developed an optical elastography technique that could revolutionize the accuracy and ease to which health professionals can detect biomechanical alterations of cells and tissues.

11 Nov 2020

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver.

11 Nov 2020

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

St Petersburg University researchers, led by Professor Raul R. Gainetdinov, Director of the Institute of Translational Biomedicine and Academic Supervisor of the St Petersburg University Hospital, have found a new role for recently discovered neurotransmitter system that uses the trace amine-associated receptor 5 (TAAR5) for neurotransmission.

11 Nov 2020

$4 million NIH grant supports research for tackling teenage depression

According to the National Institute of Mental Health (NIMH), in 2017 approximately 13% of adolescents in the United States, or 3.2 million children aged 12 to 17, had at least one major episode of depression.

11 Nov 2020

Lowest risk for autism associated with mid-levels of immune marker measured at birth

The causes of autism spectrum disorder (ASD) - including genetic and environmental factors - are not entirely understood. Many studies have already shown that serious maternal infection during pregnancy is associated with increased risk for offspring in both people and animals.

10 Nov 2020

Study could provide a new tool to predict relapse in bipolar disorder

Relapse in people with bipolar disorder can be predicted accurately by their tendency towards having pessimistic beliefs, according to a study published today in eLife.

10 Nov 2020

Study uncovers mechanisms behind premature menopause's link to cardiovascular disease

Menopause that occurs before a woman is 40 years old accelerates aging and is a risk factor for cardiovascular disease.

10 Nov 2020

Semi-automated approach accelerates artificial organoid growth and selection

The method currently used to produce stem cell-derived tissues has a very limited throughput. By semi-automating tissue differentiation, researchers from MIPT and Harvard have made the process nearly four times faster, without compromising on quality.

10 Nov 2020

Repairing brain damage caused by MS

Neurological symptoms as a result of Multiple Sclerosis (MS), such as loss of cognitive or motor function, lead to a great many problems for over 2.5 million people worldwide.

10 Nov 2020

Bioconductive, neuron-growing ink offers hope for people with nerve injury

Researchers have developed a neuron-growing ink that uses the body’s own electrical signals to precisely guide the growth of nerve cells.

10 Nov 2020

Medical Science News

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

Researchers identify new prognostic markers for colon cancer

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

Study indicates the role of Polβ enzyme in cognitive development

Study: Sleep loss hijacks the brain's ability to unlearn fear-related memories

Synthetic protein nanoparticle may treat aggressive brain cancer

Gene signature may help develop new therapies against advanced prostate cancer

Study may lead to new therapies that accelerate removal of cellular debris from the brain

Study: SphK2 enzyme regulates immune cell responses during viral infection

“Molecular volume knob” in the brain helps with learning, memory

Optical technique could transform accuracy and detection of biomechanical alterations of cells

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

$4 million NIH grant supports research for tackling teenage depression

Lowest risk for autism associated with mid-levels of immune marker measured at birth

Study could provide a new tool to predict relapse in bipolar disorder

Study uncovers mechanisms behind premature menopause's link to cardiovascular disease

Semi-automated approach accelerates artificial organoid growth and selection

Repairing brain damage caused by MS

Bioconductive, neuron-growing ink offers hope for people with nerve injury

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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