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SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

Researchers identify key gene necessary for cells to consume and destroy viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system's ability to combat viral infections, such as those fueling the ongoing COVID-19 pandemic.

17 Dec 2020

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, colonize distant organs, and form distant metastasis.

17 Dec 2020

Specific genetic target could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

People with ADHD tendencies are more sensitive to insomnia, severe functional impairments

Individuals with high ADHD-traits that do not meet the criteria for a diagnosis are less able to perform tasks involving attentional regulation or emotional control after a sleepless night than individuals with low ADHD-traits, a new study from Karolinska Institutet published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging reports.

17 Dec 2020

Novel method reveals the synaptic basis for feature selectivity

A common analogy used to describe the brain is that it consists of tiny interconnected computers.

17 Dec 2020

Researchers identify neurons that regulate nausea-like responses in mice

At some point, everyone experiences nausea. Whether it occurs after unwisely eating a week-old slice of pizza or as an accompaniment to a serious infection, that queasy, unsettling sensation centered around the stomach is a signal that something is amiss within the body and typically portends a bout of vomiting.

17 Dec 2020

Researchers explain the role of enzyme that facilitates appropriate development of mouse embryo

The body plan of an organism, crafted over millennia of evolutionary trial and error, is so exquisitely fine-tuned that even a subtle deviation can be detrimental to individual survival and reproductive success.

17 Dec 2020

Researchers examine proteins involved in SARS-CoV-2 infection

Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate.

17 Dec 2020

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Fractured sleep, daytime sleepiness and other signs of disturbance in one's circadian rhythm are common complaints of people with Alzheimer's disease, and the problems only get worse as the disease progresses.

17 Dec 2020

Researchers use noninvasive imaging to show variations in renal blood flow

Renal blood flow changes throughout the day in tandem with the body's circadian clock, with the increasing flow during daytime hours and decreasing flow in the evening and into the night.

17 Dec 2020

Researchers use new method to deliver anti-cancer drug to suppress tumor growth

Targeting drugs to cancer tissues is a major challenge in cancer treatment. Mesenchymal stem cells (MSCs) are known for their ability to find and target tumor cells in the body, but using MSCs for drug delivery has been tricky, because upon loading with drugs, MSCs lose their viability and migratory ability.

17 Dec 2020

Scientists demonstrate a promising strategy for treating lymphomas

Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes.

16 Dec 2020

NET study: New theranostic approach effective in reducing tumor volume and extending lifespan

A pair of copper radionuclides that target the somatostatin receptor overexpressed in neuroendocrine tumors has proven successful in identifying tumors and improving survival.

16 Dec 2020

Potency of neutralizing antibodies predicts COVID-19 severity and survival

Understanding the body's immune response to SARS-CoV-2, the virus that causes COVID-19, is key to developing effective treatments and long-lasting vaccines.

16 Dec 2020

New screening platform can be used to discover more effective drugs for type 1 diabetes

With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving.

16 Dec 2020

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Maresin and resolvin, produced by the body from omega-3 fatty acids, can help repair tissue damaged by periodontal disease.

16 Dec 2020

Researchers identify new biomarkers associated with incident heart failure

Researchers at the University of Eastern Finland and Kuopio University Hospital have discovered several new biomarkers that are associated with incident heart failure.

16 Dec 2020

Mass testing is not a ‘silver bullet’ for managing SARS-CoV-2 transmission, say researchers

A team of researchers from various institutions in France recently used a mathematical model to assess the impact of mass testing in controlling the SARS-CoV-2 epidemic. They evaluated the potential impact of mass testing campaigns in an epidemic rebound scenario at the end of the ongoing lockdown in Metropolitan France.

16 Dec 2020

Medical Science News

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers identify key gene necessary for cells to consume and destroy viruses

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Specific genetic target could help explain the variation in COVID-19 effects

Study shows how melanomas assist T cells from identifying and killing tumor cells

People with ADHD tendencies are more sensitive to insomnia, severe functional impairments

Novel method reveals the synaptic basis for feature selectivity

Researchers identify neurons that regulate nausea-like responses in mice

Researchers explain the role of enzyme that facilitates appropriate development of mouse embryo

Researchers examine proteins involved in SARS-CoV-2 infection

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Researchers use noninvasive imaging to show variations in renal blood flow

Researchers use new method to deliver anti-cancer drug to suppress tumor growth

Scientists demonstrate a promising strategy for treating lymphomas

NET study: New theranostic approach effective in reducing tumor volume and extending lifespan

Potency of neutralizing antibodies predicts COVID-19 severity and survival

New screening platform can be used to discover more effective drugs for type 1 diabetes

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Researchers identify new biomarkers associated with incident heart failure

Mass testing is not a ‘silver bullet’ for managing SARS-CoV-2 transmission, say researchers

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