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New vaccination strategy targets toxic molecules released by all Staphylococcal bacteria

Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.

30 Jun 2020

SAFB1 may be a diagnostic marker for neurodegenerative diseases, shows study

Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease.

30 Jun 2020

Researchers identify new step in brain cell mechanism that shows promise for treating epilepsy

Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy.

30 Jun 2020

Newly identified molecules can help develop COVID-19 therapeutics

SARS-CoV-2, the coronavirus causing the global COVID-19 pandemic, uses a protein called polymerase to replicate its genome inside infected human cells.

30 Jun 2020

Researchers develop new coatings for implants to make them more compatible

New coatings on implants could help make them more compatible. Researchers at the Martin Luther University Halle-Wittenberg (MLU) have developed a new method of applying anti-inflammatory substances to implants in order to inhibit undesirable inflammatory reactions in the body.

30 Jun 2020

Glitches in DNA replication have important implications for treating cancer

USC researchers peering deep inside a living cell have discovered something surprising: Its system for preventing genetic damage linked to diseases can fail so badly that the cell would be better off without it.

30 Jun 2020

Engineered immune cells attack solid-tumor cancer cells from humans and mice

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia.

30 Jun 2020

Bioengineered uterine tissue can support normal pregnancies, study shows

In new research from the Wake Forest Institute for Regenerative Medicine (WFIRM), scientists have shown that bioengineered uteri supported fertilization, fetal development, and live birth with normal offspring.

29 Jun 2020

Overactive neutrophils may drive life-threatening blood clots in some COVID-19 patients

Scientists have new evidence that overactive neutrophils--a common type of circulating immune cell--may drive the life-threatening blood clots and inflammation that occur in some patients with COVID-19.

29 Jun 2020

Research reveals key role of fat cells in renal failure-associated cardiomyopathy

New research from a team at the Marshall University Joan C. Edwards School of Medicine reveals the central role of fat cells in the systemic oxidant stress observed in renal failure-associated cardiomyopathy.

29 Jun 2020

Innovative technology permits faster, cheaper toxicological screening of drug candidates

Ramot at Tel Aviv University has signed a collaboration agreement with Bayer to develop and validate a platform for in vitro cardiotoxicity screening, using human heart tissues 3D-printed in Prof. Tal Dvir's Laboratory for Tissue Engineering and Regenerative Medicine at Tel Aviv University.

29 Jun 2020

Study unravels CNL6 mystery in Batten disease

Batten disease is a family of 13 rare, genetically distinct conditions. Collectively, they are the most prevalent cause of neurodegenerative disease in children, affecting 1 in 12,500 live births in the U.S. One of the Batten disease genes is CLN6.

29 Jun 2020

Researchers show how upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

New eye drops could prevent vision loss after retinal vein occlusion

Researchers at Columbia University Irving Medical Center have developed eye drops that could prevent vision loss after retinal vein occlusion, a major cause of blindness for millions of adults worldwide.

29 Jun 2020

Older people less likely to share memories of their past experiences

By the time people reach a certain age, they've accumulated enough life experience to have plenty of stories to tell about life "back in their day."

29 Jun 2020

The gut shields the liver from fructose-induced lipogenesis

After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

29 Jun 2020

Remodeling may make neurons more prone to Alzheimer's disease

Neurons that regularly remodel are more prone to Alzheimer's disease and die when that remodeling goes awry, a new study suggests. The work is the first to track the progression of Alzheimer's at the genetic and molecular levels within neurons vulnerable to the disease.

29 Jun 2020

Human Brain Project starts final phase as EU-funded FET Flagship

The Human Brain Project announces the start of its final phase as an EU-funded FET Flagship. The European Commission has signed a grant agreement to fund the HBP with 150 million Euros from now until 2023.

29 Jun 2020

Nanofiber filters can be reused through a simple ethanol cleaning process

As the COVID-19 pandemic spreads around the world, masks have become an essential personal hygiene product as the first line of defense to protect one's respiratory system against the viruses and germs that spread through droplets in the air.

29 Jun 2020

NUS researchers discover protein that promotes cancer progression

Cancers arise when the genetic code of normal cells is altered, causing excessive growth. Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a protein that drives the growth of cancers of the esophagus or liver by altering the genetic code in a novel way.

29 Jun 2020