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Researchers use brain connectome to reassess neuroimaging findings of Alzheimer's disease

Already affecting more than five million Americans older than 65, Alzheimer's disease is on the rise and expected to impact more than 13 million people by 2050.

17 Dec 2018

A new type of 'painless' adhesive for biomedical applications

Pulling off a Band-Aid may soon get a lot less painful. Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences and Xi'an Jiaotong University in China have developed a new type of adhesive that can strongly adhere wet materials -- such as hydrogel and living tissue -- and be easily detached with a specific frequency of light.

14 Dec 2018

Experimental HIV vaccine strategy works in non-human primates, research shows

For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research, published in Immunity, shows that their experimental vaccine strategy works in non-human primates.

14 Dec 2018

Using machine learning to predict risk of developing life-threatening infections

Staphylococcus epidermidis is an ubiquitous colonizer of healthy human skin, but it is also a notorious source of serious nosocomial infections with indwelling devices and surgical procedures such as hip replacements.

14 Dec 2018

Folate deficiency creates more damaging chromosomal abnormalities than previously known

Folate deficiency creates more problems in connection with DNA replication than researchers had hitherto assumed, researchers from the University of Copenhagen show in a new study.

14 Dec 2018

Magnesium may play important role in optimizing vitamin D levels, study shows

A randomized trial by Vanderbilt-Ingram Cancer Center researchers indicates that magnesium optimizes vitamin D status, raising it in people with deficient levels and lowering it in people with high levels.

14 Dec 2018

New computer model helps predict course of the disease in prostate cancer patients

How does a normal cell turn into a deadly cancer? Seeking an answer to this question, and working alongside other international working groups, researchers from Charité - Universitätsmedizin Berlin examined the tumor genomes of nearly 300 prostate cancer patients.

14 Dec 2018

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Genetically diverse bacterial strains that cause urinary tract infections differ in their ability to trigger protective immune responses in mice, potentially explaining why these infections frequently recur in many patients, according to a study published December 13 in the open-access journal PLOS Pathogens by Thomas Hannan and Scott Hultgren of Washington University School of Medicine, and colleagues.

14 Dec 2018

Weakened metabolism of immune T cells may account for serious complications in elderly

The elderly suffer more serious complications from infections and benefit less from vaccination than the general population.

14 Dec 2018

Shining new light on neuron firing

Scientists have plenty of ways to watch as individual neurons in a brain fire, sending electrical signals from one to the next, but they all share a basic problem.

14 Dec 2018

Diets containing GM maize have no harmful effects on health or metabolism of rats

For six months, rats were fed a diet containing either GM maize (MON 810 or NK603) or non-GM maize, in varying concentrations.

14 Dec 2018

New findings could help develop new immunotherapies against cancer

NK cells, or natural killer cells, play an important role in the body's defences against cancer and various infections.

14 Dec 2018

Genetically modified pigs could limit replication of classical swine fever virus, study shows

Researchers have developed genetically modified pigs that are protected from classical swine fever virus, according to a study published December 13 in the open-access journal PLOS Pathogens by Hongsheng Ouyang of Jilin University, and colleagues.

14 Dec 2018

New drug shows promise in treating sarcomas

A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports.

14 Dec 2018

New research lays out potential path for treatment of Huntington’s disease

New research gives scientists a clearer picture of what is happening in the brains of people with Huntington's disease and lays out a potential path for treatment.

14 Dec 2018

UA scientists uncover biological processes leading to rare brain disorder in babies

Babies born with pontocerebellar hypoplasia type Ib often do not survive past one year. Born with an underdeveloped brain, infants struggle to move, feed and even breathe.

14 Dec 2018

Recent developments and challenges in hMAT inhibitors

Zhu et al. have reviewed the recent developments in the knowledge about the binding, inhibitory mechanisms and structure-activity relationships of hSERT, hNET and hDAT, which are primary human monoamine transporters hMATs.

14 Dec 2018

Genetic marker, predictor of early relapse in common childhood cancer discovered

Nova Southeastern University researchers recently discovered that by testing the level of NER (nucleotide excision repair) gene expression, pediatric oncologists can determine the likelihood of early relapse (less than three years) in their acute lymphoblastic leukemia patients.

14 Dec 2018

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

A UCL-led study has confirmed that some vials of a hormone used in discontinued medical treatments contained seeds of a protein implicated in Alzheimer's disease, and are able to seed amyloid pathology in mice.s

14 Dec 2018

Study uncovers new genetic clues to frontotemporal dementia

Unlike the more common Alzheimer's disease, frontotemporal dementia tends to afflict young people. It accounts for an estimated 20 percent of all cases of early-onset dementia.

13 Dec 2018

Medical Science News

Researchers use brain connectome to reassess neuroimaging findings of Alzheimer's disease

A new type of 'painless' adhesive for biomedical applications

Experimental HIV vaccine strategy works in non-human primates, research shows

Using machine learning to predict risk of developing life-threatening infections

Folate deficiency creates more damaging chromosomal abnormalities than previously known

Magnesium may play important role in optimizing vitamin D levels, study shows

New computer model helps predict course of the disease in prostate cancer patients

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Weakened metabolism of immune T cells may account for serious complications in elderly

Shining new light on neuron firing

Diets containing GM maize have no harmful effects on health or metabolism of rats

New findings could help develop new immunotherapies against cancer

Genetically modified pigs could limit replication of classical swine fever virus, study shows

New drug shows promise in treating sarcomas

New research lays out potential path for treatment of Huntington’s disease

UA scientists uncover biological processes leading to rare brain disorder in babies

Recent developments and challenges in hMAT inhibitors

Genetic marker, predictor of early relapse in common childhood cancer discovered

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

Study uncovers new genetic clues to frontotemporal dementia

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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