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Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

In what is believed to be the most comprehensive molecular characterization to date of the most common - and often treatment-resistant - form of kidney cancer, researchers at Johns Hopkins' departments of pathology and oncology, Johns Hopkins Kimmel Cancer Center, and the Johns Hopkins University School of Medicine report evidence for at least three distinct subtypes of clear cell renal cell carcinoma (ccRCC), along with new revelations about the proteins that define them.

From Johns Hopkins Medicine 31 Oct 2019

GLP-1 receptors could serve as targets for novel medications to treat opioid use disorder

Opioid use disorder and overdose deaths are a major public health crisis in the United States. While medication-assisted treatments for opioid use disorder exist, these treatments remain inadequate for many patients, resulting in a high rate of relapse following detoxification.

31 Oct 2019

Molecular gatekeepers that regulate calcium ions vital for muscle health and repair

Calcium ions are essential to how muscles work effectively, playing a starring role in how and when muscles contract, tap energy stores to keep working and self-repair damage.

31 Oct 2019

Researchers discover key mechanism in insulin release by cholesterol metabolite

Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells.

31 Oct 2019

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the 'runaway train' that is Parkinson's disease.

31 Oct 2019

Study identifies a kinase as potential target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies.

31 Oct 2019

Optometrists reduce opioid prescription without increasing pain

Optometrists at the University of Michigan have introduced a new approach to prescribing opioids in an effort to help curb the nation’s opioid epidemic.

31 Oct 2019

REANIMA project may overturn paradigms that underlie regenerative cardiology research

Research into new endogenous mechanisms of tissue regeneration is an innovative research avenue in cardiac regeneration.

31 Oct 2019

New deep learning tool will advance personalized medicine for musculoskeletal diseases

Personalized medicine has stirred the imagination of drugs and therapies that are individually tailored to patients.

31 Oct 2019

Factor responsible for formation of white blood cells has regulatory effect on adaptive immunity

Granulocyte colony-stimulating factor, which causes division and differentiation of bone marrow cells depending on the body's need for leukocytes, has a significant regulatory effect not only on innate, but also on adaptive immunity.

31 Oct 2019

Researchers identify genes linked to most severe symptoms of multiple sclerosis

In a bid to determine factors linked to the most debilitating forms of multiple sclerosis, Johns Hopkins Medicine researchers say they have identified three so-called "complement system" genes that appear to play a role in MS-caused vision loss.

From Johns Hopkins Medicine 31 Oct 2019

Study finds altered brain asymmetry in autism spectrum disorder

The left and right halves of our brains develop differently, as each hemisphere 'specialises' in certain functions. For example, for most people the left hemisphere--controlling the right hand--is dominant for language.

31 Oct 2019

LLNL leads multi-institutional collaboration in modeling protein interactions linked to cancer

Computational scientists, biophysicists and statisticians from Lawrence Livermore National Laboratory and Los Alamos National Laboratory are leading a massive multi-institutional collaboration that has developed a machine learning-based simulation for next-generation supercomputers capable of modeling protein interactions and mutations that play a role in many forms of cancers.

31 Oct 2019

Education level and socioeconomic status can predict thinking and memory performance

How well eight-year-olds score on a test of thinking skills may be a predictor of how they will perform on tests of thinking and memory skills when they are 70 years old, according to a study published in the October 30, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology.

31 Oct 2019

New study sheds light on artificial networks and human face recognition

Our brains are so primed to recognize faces - or to tell people apart - that we rarely even stop to think about it, but what happens in the brain when it engages in such recognition is still far from understood. In a new study reported today in Nature Communications, researchers at the Weizmann Institute of Science have shed new light on this issue.

30 Oct 2019

Exploring motivational factors for endurance running

Endurance running is often seen as a welcome escape from everyday life. But extraordinary experiences, such as running ultra-marathons, are not untouched by the competitive nature of contemporary consumer culture, a new thesis from Lund University in Sweden argues.

30 Oct 2019

Drug delivery still has great development potential

Nanocapsules and other containers can transport drugs through a patient's body directly to the origin of the disease and release them there in a controlled manner. Such sophisticated systems are occasionally used in cancer therapy. Because they work very specifically, they have fewer side effects than drugs that are distributed throughout the entire organism.

30 Oct 2019

Medical Science News

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

GLP-1 receptors could serve as targets for novel medications to treat opioid use disorder

Molecular gatekeepers that regulate calcium ions vital for muscle health and repair

Researchers discover key mechanism in insulin release by cholesterol metabolite

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Study identifies a kinase as potential target to treat heart failure

Optometrists reduce opioid prescription without increasing pain

REANIMA project may overturn paradigms that underlie regenerative cardiology research

New deep learning tool will advance personalized medicine for musculoskeletal diseases

Factor responsible for formation of white blood cells has regulatory effect on adaptive immunity

Researchers identify genes linked to most severe symptoms of multiple sclerosis

Study finds altered brain asymmetry in autism spectrum disorder

LLNL leads multi-institutional collaboration in modeling protein interactions linked to cancer

Education level and socioeconomic status can predict thinking and memory performance

New study sheds light on artificial networks and human face recognition

Exploring motivational factors for endurance running

Drug delivery still has great development potential

Researchers develop new therapeutic concept for treatment of temporal lobe epilepsy

New biomarker can track mitochondrial activity in lung tumors

Shared abnormalities found in brain's control circuit of patients with mood, anxiety disorders

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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