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MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

A Massachusetts General Hospital research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma - the second most common bone cancer in children and young adults - unleashes tumor growth.

2 Aug 2018

Study of neuroprotective microRNAs may lead to new avenues for treating tauopathies

Alzheimer's disease is an increasingly prevalent, neurodegenerative condition that erodes memory and other cognitive functions. Treatments for this complex disease have been elusive, although researchers have previously uncovered its main biological features: amyloid-beta plaques and tau tangles.

2 Aug 2018

Mushrooms from the Far East area could be used to design novel anti-cancer drugs

Mushrooms from the Far East area contain the natural chemical compounds, which could be used for the design of the novel drugs with highly specific anti-tumor activities and low-toxicity.

2 Aug 2018

Simple pH imbalance could be a root of Alzheimer’s disease, mouse study shows

Johns Hopkins Medicine scientists say they have found new evidence in lab-grown mouse brain cells, called astrocytes, that one root of Alzheimer's disease may be a simple imbalance in acid-alkaline - or pH - chemistry inside endosomes, the nutrient and chemical cargo shuttles in cells.

2 Aug 2018

Mice study shows mother's dengue immunity protects unborn from ZIKA infection

Dengue and Zika viruses are closely related and carried by mosquitos. In infested subtropical and tropical areas, dengue transmission often precedes Zika virus infection, suggesting that women who previously acquired dengue immunity may be bitten by ZIKV-carrying mosquitoes during pregnancy.

2 Aug 2018

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes.

2 Aug 2018

Gut bacteria may be important determinant of weight loss, study suggests

A preliminary study published in the August issue of Mayo Clinic Proceedings suggests that, for some people, specific activities of gut bacteria may be responsible for their inability to lose weight, despite adherence to strict diet and exercise regimens.

2 Aug 2018

Study: Obesity may play role in flu transmission, not just disease severity

Obesity increases a person's risk for severe complications from influenza, including hospitalization and even death.

2 Aug 2018

Scientists develop simple, innovative method to convert white fat to brown fat

Brown fat tissue in the body can burn enormous amounts of energy to generate heat, and studies in humans and animals have suggested that increasing the amount of healthy brown fat might help weight management and reduce symptoms of diabetes.

2 Aug 2018

Researchers reveal molecular mechanisms that make people with EV prone to ß-HPVs

Keratinocyte skin cells are common targets of the beta subtype of human papilloma virus. This usually harmless infection causes skin disease in people with rare gene mutations.

2 Aug 2018

Researchers uncover new mechanisms underlying common kidney cancer in children

Connecting two previously unrelated insights about the formation of pediatric kidney cancer, researchers at UT Southwestern Medical Center have uncovered the means by which the cancer continues to grow, providing potential targets for more effective treatments in the future.

2 Aug 2018

Researchers discover key piece for slowing colorectal cancer subtype

Inhibiting the Jagged 1 protein in mice prevents the proliferation and growth of colon and rectal tumors. What is more, this approach to the disease permits the removal of existing tumors.

2 Aug 2018

3D-printed implants appear to guide regrowth of missing bone in lab animals

Chemically coated, ceramic implants successfully guided the regrowth of missing bone in lab animals while "steadily dissolving," researchers report.

2 Aug 2018

Protein known to drive nerve cell survival may protect children from Duchenne cardiomyopathy

A protein known to drive nerve cell survival in the brain and spinal cord might also protect failing hearts in children and young adults with Duchenne muscular dystrophy, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions, a premier global exchange of the latest advances in basic cardiovascular science.

2 Aug 2018

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs, according to a study published in Nature Communications this month by researchers from the Perelman School of Medicine at the University of Pennsylvania.

2 Aug 2018

Medical Science News

MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

Study of neuroprotective microRNAs may lead to new avenues for treating tauopathies

Mushrooms from the Far East area could be used to design novel anti-cancer drugs

Simple pH imbalance could be a root of Alzheimer’s disease, mouse study shows

Mice study shows mother's dengue immunity protects unborn from ZIKA infection

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

Gut bacteria may be important determinant of weight loss, study suggests

Study: Obesity may play role in flu transmission, not just disease severity

Scientists develop simple, innovative method to convert white fat to brown fat

Researchers reveal molecular mechanisms that make people with EV prone to ß-HPVs

Researchers uncover new mechanisms underlying common kidney cancer in children

Researchers discover key piece for slowing colorectal cancer subtype

3D-printed implants appear to guide regrowth of missing bone in lab animals

Protein known to drive nerve cell survival may protect children from Duchenne cardiomyopathy

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

Researchers discover new, rare type of cell in the human airway

Women with PCOS more likely to have an autistic child

Researchers find possible active substance that may cure hepatitis E

New method to construct brain networks improves accuracy of diagnosing Alzheimer's disease

Tests show Drexel's polymer crystal nanocapsules can last longer in bloodstream

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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