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Early microstructural changes can help predict long-term recovery from spinal cord injury

A trauma to the spinal cord, quickly leads to a progressive loss of nerve tissue. This not only affects the injured area, but over time affects also other parts of the spinal cord and even the brain.

9 Mar 2018

Engineers develop optical tool that can read metabolism at subcellular resolution

Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage. Now, a team led by engineers at Tufts University School of Engineering has opened a window into the cell by developing an optical tool that can read metabolism at subcellular resolution, without having to perturb cells with contrast agents, or destroy them to conduct assays.

9 Mar 2018

Impaired transport processes in neurons contribute to neurodegenerative disorders

Two partners have to find their way to each other in order to transport substances to the remote ends of special nerve fibers to maintain their function. If this partnering process is disturbed, the cells may die in the worst case, resulting in neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy.

9 Mar 2018

Novel screening tool aids search for curative kidney treatment

Researchers have developed a screening tool for identifying compounds that restore functionality of the protein that is dysfunctional in Alport syndrome.

9 Mar 2018

Surprise discovery may lead potential treatment for multiple sclerosis

A surprise finding by medical scientists may lead to the development of a possible treatment for multiple sclerosis (MS).

9 Mar 2018

Study finds link between women having children and shorter telomeres

A recent study by George Mason University researchers in the Department of Global and Community Health found that women who have given birth have shorter telomeres compared to women who have not given birth.

9 Mar 2018

Mice study illustrates potential risks associated with prion transmission

Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations.

9 Mar 2018

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists at The Scripps Research Institute have now shown a path to developing treatments for disease subtype CMT2D.

8 Mar 2018

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Scientists uncovered a high-resolution map of the wiring inside the mouse brain's thirst center. With these blueprints, they could trick mice into becoming light or heavy water drinkers.

8 Mar 2018

Air pollution exposure during fetal life related to brain abnormalities, cognitive impairment in children

A new study performed in the Netherlands has linked exposure to residential air pollution during fetal life with brain abnormalities that may contribute to impaired cognitive function in school-age children. The study, published in Biological Psychiatry, reports that the air pollution levels related to brain alterations were below those considered to be safe.

8 Mar 2018

Study seeks to examine whether gut bacteria cause brain dysfunction in sepsis patients

Surviving a critical illness is no small feat, but it's only half the battle for many patients. Serious complications can still result after an illness appears to have cleared.

8 Mar 2018

Discovery may lead to effective research and better treatments for Ebola, other viral diseases

University of Alberta researchers have found the Ebola polymerase (enzyme), which may lead to more effective research and better treatments for the often fatal infection, and other related viral diseases.

8 Mar 2018

Study shows how fly's circadian clock network takes temperature cues to control sleep

Circuits in the brain act as an internal clock to tell us it is time to sleep and to control how long we then stay asleep. A new study in flies suggests a part of that clock constantly monitors changes in external temperature and integrates that information into the neural network controlling sleep.

8 Mar 2018

Blood samples can soon reflect a person’s lifestyle

People who use moist snuff 'snus' have significantly higher levels of the protein cornulin in their blood than non-snusers. This previously unknown relationship was found in a new study from Umeå University, Sweden. Whether higher levels per se increase the risk of disease has, however, not yet been clarified.

8 Mar 2018

Researchers examine how well category-learning works in a stressful episode

When people have to assess a situation within seconds, it helps them to draw on learned categories. Psychologists from the Ruhr-Universität Bochum examined with the help of electroencephalography (EEG) how well category-learning works in a stressful episode.

8 Mar 2018

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood.

8 Mar 2018

New study examines origin of cryptococcosis within the central nervous system

A particular fungal infection is responsible for more than 220,000 cases of cryptococcosis worldwide each year in people with HIV and AIDS, with nearly 181,000 of those resulting in death.

8 Mar 2018

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

Sanford Burnham Prebys Medical Research Institute researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function.

8 Mar 2018

High-resolution fMRI provides clues about age-related memory differences

As we get older, it's not uncommon to experience "senior moments," in which we forget where we parked our car or call our children by the wrong names. And we may wonder: Are these memory lapses a normal part of aging, or do they signal the early stages of a severe disorder such as Alzheimer's disease? Currently, there's no good way to tell.

8 Mar 2018

Golgi stress signaling pathway found in cells with Huntington’s disease

Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants.

8 Mar 2018

Medical Science News

Early microstructural changes can help predict long-term recovery from spinal cord injury

Engineers develop optical tool that can read metabolism at subcellular resolution

Impaired transport processes in neurons contribute to neurodegenerative disorders

Novel screening tool aids search for curative kidney treatment

Surprise discovery may lead potential treatment for multiple sclerosis

Study finds link between women having children and shorter telomeres

Mice study illustrates potential risks associated with prion transmission

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Air pollution exposure during fetal life related to brain abnormalities, cognitive impairment in children

Study seeks to examine whether gut bacteria cause brain dysfunction in sepsis patients

Discovery may lead to effective research and better treatments for Ebola, other viral diseases

Study shows how fly's circadian clock network takes temperature cues to control sleep

Blood samples can soon reflect a person’s lifestyle

Researchers examine how well category-learning works in a stressful episode

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

New study examines origin of cryptococcosis within the central nervous system

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

High-resolution fMRI provides clues about age-related memory differences

Golgi stress signaling pathway found in cells with Huntington’s disease

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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