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Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Many breast cancer patients do not feel fully informed about their treatment options, say researchers

A research team in the U.S. has found that most women who undergo breast cancer operations do not feel fully informed about their treatment options when they decide on which procedure to undergo.

18 Dec 2017

A guide to Severe Combined Immunodeficiency Disease, review released

A new review published today in the Canadian Medical Association Journal provides guidance on Severe Combined Immunodeficiency Disease (SCID), a deadly and rare disease that is potentially curable if detected early.

18 Dec 2017

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Mature cells also play role in initiating cancer, study suggests

Rapidly dividing, yet aberrant stem cells are a major source of cancer. But a new study suggests that mature cells also play a key role in initiating cancer - a finding that could upend the way scientists think about the origin of the disease.

18 Dec 2017

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Study reveals biology behind why muscle stem cells respond differently to aging or injury

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute describes the biology behind why muscle stem cells respond differently to aging or injury.

15 Dec 2017

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, and how to improve the treatment of illness in the future.

15 Dec 2017

Scientists use nanoparticles to fight Mucoviscidosis

Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination.

15 Dec 2017

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level.

15 Dec 2017

Scientists use AI-enhanced microscope system to quickly, accurately identify bacteria

Microscopes enhanced with artificial intelligence could help clinical microbiologists diagnose potentially deadly blood infections and improve patients' odds of survival, according to microbiologists at Beth Israel Deaconess Medical Center

15 Dec 2017

Researchers uncover THOR gene involved in cancer development

It turns out Thor, the Norse god of thunder and the Marvel superhero, has special powers when it comes to cancer too.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Researchers have glimpsed how the toxic protein clusters that are associated with Parkinson's Disease disrupt the membranes of healthy brain cells, creating defects in the cell walls and eventually causing a series of events that induce neuronal death.

15 Dec 2017

Aging brain's failure to coordinate deep-sleep brainwaves makes older adults forget

Like swinging a tennis racket during a ball toss to serve an ace, slow and speedy brainwaves during deep sleep must sync up at exactly the right moment to hit the save button on new memories, according to new UC Berkeley research.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

Extracellular vesicles can be used to effectively delay progression of kidney damage

Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage in mice with a type of chronic kidney disease.

15 Dec 2017

Rare gene mutation gives rise to low sensitivity to pain

Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by conditions such as lower back pain and osteoarthritis is one of the most prominent causes of disability worldwide, as assessed by the Global Burden of Disease reviews.

15 Dec 2017

A daily cup of hot tea may lower glaucoma risk

According to a small study published online yesterday in the British Journal of Ophthalmology, drinking at least one cup of hot tea daily may be associated with a considerably lower risk of contracting glaucoma, a serious eye condition.

15 Dec 2017

Medical Science News

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

Many breast cancer patients do not feel fully informed about their treatment options, say researchers

A guide to Severe Combined Immunodeficiency Disease, review released

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Mature cells also play role in initiating cancer, study suggests

Excessive copper in diabetes impedes ability to make new blood vessels

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

Study reveals biology behind why muscle stem cells respond differently to aging or injury

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

Scientists use nanoparticles to fight Mucoviscidosis

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

Scientists use AI-enhanced microscope system to quickly, accurately identify bacteria

Researchers uncover THOR gene involved in cancer development

Researchers examine human mutations' impact on therapeutic effect of medicine

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Aging brain's failure to coordinate deep-sleep brainwaves makes older adults forget

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Extracellular vesicles can be used to effectively delay progression of kidney damage

Rare gene mutation gives rise to low sensitivity to pain

A daily cup of hot tea may lower glaucoma risk

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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