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Researchers demystify interdomain communication pathway in Hsp70 protein

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has demystified the pathway of interdomain communication in a family of proteins known as Hsp70s - a top target of dozens of research laboratories trying to develop new anti-cancer drugs, antibiotics and treatments for Alzheimer's and Parkinson's diseases.

30 Aug 2017

Study sheds new light on gene fusion in bladder and brain cancer

A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.

30 Aug 2017

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Scientists at Children's Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease.

29 Aug 2017

Tiny tears in membranes of bone cells may be key to strong bones

The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say.

29 Aug 2017

Immunotherapy that uses existing cancer drugs in a new way delivers promising results

Immunotherapy is an emerging field in the global fight against cancer, even though scientists and clinicians have been working for decades to find ways to help the body's immune system detect and attack cancerous cells.

29 Aug 2017

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukemia patients who have undergone stem cell transplantation.

29 Aug 2017

New study pinpoints origin of abnormalities in autism spectrum disorder

The origins of autism remain mysterious. What areas of the brain are involved, and when do the first signs appear? New findings published in Biological Psychiatry brings us closer to understanding the pathology of autism, and the point at which it begins to take shape in the human brain.

29 Aug 2017

Spaceflight causes many significant changes in the human body, research shows

A team of scientists from Russia and Canada has analyzed the effect of space conditions on the protein composition in blood samples of 18 Russian cosmonauts. The results indicated many significant changes in the human body caused by space flight.

29 Aug 2017

Magnetic stimulation of the prefrontal cortex improved test subjects’ evaluation of own performance

Researchers at Aalto University and the University of Helsinki have succeeded for the first time ever in affecting metacognition of a tactile working memory task by combining neural pathway imaging and magnetic stimulation of the brain.

29 Aug 2017

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

Parkinson's disease is an insidious disease: by the time it manifests as the typical motor dysfunctions such as tremors or muscle rigidity, portions of the brain have already been irreversibly destroyed.

29 Aug 2017

Researchers reveal reason for reduced release of satiety hormones in obese people

Individuals with severe overweight have an inhibited sense of satiation - they release fewer satiety hormones than people of normal weight.

29 Aug 2017

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

New blood vessels branch out of preexisting ones is via a process called angiogenesis. Although this is essential for survival, development and wound healing, on the flip side, it also feeds and progresses malignant tumors, as well as other diseases.

29 Aug 2017

Scientists discover way to treat severe inflammation from mosquito-borne diseases

Scientists have discovered a way that could help treat severe inflammation from an infectious mosquito-borne disease during outbreaks.

29 Aug 2017

Boosting blood levels of bone-derived hormone may reverse age-related memory loss

Age-related memory loss may be reversed by boosting blood levels of osteocalcin, a hormone produced by bone cells, according to mouse studies led by Columbia University Medical Center researchers.

29 Aug 2017

New antibodies may halt key pathological mechanisms across several neurological diseases

A new kind of antibody targets a feature shared by proteins thought to cause the most damage in Alzheimer's disease, Parkinson's disease, and related conditions, creating potential for a unified treatment approach.

29 Aug 2017

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

Is telomere length associated with the cognitive response to a lifestyle intervention? Supporting evidence from the FINGER trial.

29 Aug 2017

Study reveals new opportunities for treatment of Type 2 diabetes

Bacteria may be responsible for more than we suspect. Especially when it comes to inflammatory diseases such as Type 2 diabetes.

29 Aug 2017

Traditional Chinese herb may hold key to new osteoporosis therapy for preventing bone loss

An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects.

29 Aug 2017

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

The benefit of lowering low-density lipoprotein (LDL) cholesterol depends on how it is lowered, according to late-breaking results from a naturally randomised genetic trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in JAMA.

29 Aug 2017

Mammal embryos discard paternal mitochondria within days of fertilization, new study shows

Mammal embryos shed paternal mitochondria within days of fertilization, perhaps to ensure the offspring a healthy life, a new study shows.

29 Aug 2017

Medical Science News

Researchers demystify interdomain communication pathway in Hsp70 protein

Study sheds new light on gene fusion in bladder and brain cancer

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Tiny tears in membranes of bone cells may be key to strong bones

Immunotherapy that uses existing cancer drugs in a new way delivers promising results

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

New study pinpoints origin of abnormalities in autism spectrum disorder

Spaceflight causes many significant changes in the human body, research shows

Magnetic stimulation of the prefrontal cortex improved test subjects’ evaluation of own performance

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

Researchers reveal reason for reduced release of satiety hormones in obese people

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

Scientists discover way to treat severe inflammation from mosquito-borne diseases

Boosting blood levels of bone-derived hormone may reverse age-related memory loss

New antibodies may halt key pathological mechanisms across several neurological diseases

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

Study reveals new opportunities for treatment of Type 2 diabetes

Traditional Chinese herb may hold key to new osteoporosis therapy for preventing bone loss

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

Mammal embryos discard paternal mitochondria within days of fertilization, new study shows

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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