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Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich's ataxia (FA) measurably halted cellular damage caused by the degenerative disease.

25 Oct 2017

Higher amounts of physical activity linked to healthier blood biomarkers, study finds

It is well known that being physically active may lower risks of many diseases, such as heart disease and diabetes. In this study, the scientists studied the link between various measures of exercise and eight biomarkers that have previously related to several chronic diseases.

25 Oct 2017

Young hockey players may show post-concussion brain changes even after they return to play

Young hockey players who have suffered concussions may still show changes in the white matter of the brain months after being cleared to return to play, researchers at Western University have found through sophisticated Magnetic Resonance Imaging (MRI) techniques.

25 Oct 2017

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

A Massachusetts General Hospital research team has found a surprising potential solution to a persistent clinical problem - the healing of chronic wounds. In their report published in Wound Repair and Regeneration, the investigators from the MGH Vaccine and Immunotherapy Center describe how application of mature B lymphocytes - the immune cells best known for producing antibodies - greatly accelerated the healing of acute and chronic wounds in both diabetic and nondiabetic mice.

25 Oct 2017

Scientists discover how immune cells clear the way for nerve regeneration after injury

Immune cells are normally associated with fighting infection but in a new study, scientists have discovered how they also help the nervous system clear debris, clearing the way for nerve regeneration after injury.

25 Oct 2017

Researchers find rare genetic variants that may help explain longevity in some CF patients

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

25 Oct 2017

UCLA researchers precisely stimulate the brain to enhance recollection of distinct memories

Neuroscientists at the David Geffen School of Medicine at UCLA have discovered precisely where and how to electrically stimulate the human brain to enhance people's recollection of distinct memories. People with epilepsy who received low-current electrical pulses showed a significant improvement in their ability to recognize specific faces and ignore similar ones.

25 Oct 2017

Pre-clinical study reports promising step forward in search for non-addictive painkillers

A pre-clinical study led by Indiana University scientists reports a promising step forward in the search for pain relief methods without the addictive side effects behind the country's current opioid addiction crisis.

25 Oct 2017

Gut bacteria could hold clues to risk of developing PTSD after traumatic event

The bacteria in your gut could hold clues to whether or not you will develop posttraumatic stress disorder (PTSD) after experiencing a traumatic event.

25 Oct 2017

Pharmacist identifies protein linked to tumor growth in gallbladder cancer

Patients with gallbladder cancer often show few or no symptoms for long periods of time. As a result, the tumors are only detected at a late stage of the disease when treatment is often no longer possible.

25 Oct 2017

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a novel way to genetically engineer T cells that may be effective for treating and preventing leukemia relapse.

25 Oct 2017

Insights from NGLY1 deficiency could provide new approach to treat blood cancers

A new class of drugs for blood cancers such as leukemia and multiple myeloma is showing promise. But it is hobbled by a problem that also plagues other cancer drugs: targeted cells can develop resistance.

25 Oct 2017

Skin plays role in helping regulate blood pressure and heart rate, say scientists

Skin plays a surprising role in helping regulate blood pressure and heart rate, according to scientists at the University of Cambridge and the Karolinska Institute, Sweden. While this discovery was made in mice, the researchers believe it is likely to be true also in humans.

25 Oct 2017

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Triglycerides, a type of fat in the blood, are important for good health. But having high triglycerides might increase a person's risk of heart disease, and may be a sign of metabolic syndrome--a combination of high blood pressure, high blood sugar, and too much fat accumulation at the waist.

25 Oct 2017

Study reveals why Alzheimer's drugs fail in clinical trials

A tremendous amount of Amyloid-β peptide (Aβ) (a peptide of ～40 amino acids) accumulates in the brain of Alzheimer's disease patients. γ-Secretase inhibitors were designed to inhibit the enzymatic activity that produces Aβ. By reducing Aβ production, γ-secretase inhibitors were considered able to treat Alzheimer's disease (Aβ hypothesis).

25 Oct 2017

New discovery could speed development and approval of antiviral drugs

New research shows that a new class of antiviral drugs works by causing the virus' replication machinery to pause and backtrack, preventing the virus from efficiently replicating. This discovery, made possible by a high-throughput experimental technique called "magnetic tweezers," could speed the development and approval of related antiviral drugs.

25 Oct 2017

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New research from The University of Texas Health Science Center at San Antonio and U.S. Department of Veterans Affairs has identified the molecular mechanism that causes kidney cancer to resist drug treatment.

25 Oct 2017

Scientists get one step closer to reversing retinal degenerative diseases

Degenerative disorders affecting the retinal pigment epithelium (RPE), such as age-related macular degeneration and autosomal recessive bestrophinopathy, can ultimately lead to blindness. Some of these life-changing disorders are the result of mutations in a single gene, called BEST1.

25 Oct 2017

Researchers mine blood-based epigenetic data to gain insights into autism biology

Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.

25 Oct 2017

Weight loss following bariatric operation leads to improvements in heart health

In overweight and obese people, fat often gets deposited in the midsection of the body. Large amounts of this belly fat can lead to unhealthy changes in a heart's function and size.

25 Oct 2017

Medical Science News

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Higher amounts of physical activity linked to healthier blood biomarkers, study finds

Young hockey players may show post-concussion brain changes even after they return to play

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

Scientists discover how immune cells clear the way for nerve regeneration after injury

Researchers find rare genetic variants that may help explain longevity in some CF patients

UCLA researchers precisely stimulate the brain to enhance recollection of distinct memories

Pre-clinical study reports promising step forward in search for non-addictive painkillers

Gut bacteria could hold clues to risk of developing PTSD after traumatic event

Pharmacist identifies protein linked to tumor growth in gallbladder cancer

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

Insights from NGLY1 deficiency could provide new approach to treat blood cancers

Skin plays role in helping regulate blood pressure and heart rate, say scientists

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Study reveals why Alzheimer's drugs fail in clinical trials

New discovery could speed development and approval of antiviral drugs

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

Scientists get one step closer to reversing retinal degenerative diseases

Researchers mine blood-based epigenetic data to gain insights into autism biology

Weight loss following bariatric operation leads to improvements in heart health

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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