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Researchers create ‘protocells’ for delivering drugs to deepest tumor regions

Despite herculean efforts, cancer remains a formidable disease, with each malignant subtype responding differently to therapeutics.

11 Jan 2018

Human cardiac-muscle patches improve recovery from heart attack injury

Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery from heart attack injury.

11 Jan 2018

Clinical study investigates lifestyle biomarkers in prostate cancer survivors

Advanced glycation end products, which have been linked to many chronic diseases, including diabetes, cardiovascular disease and cancer, build up in the body from birth due to normal metabolism but are often higher in those eating the high-fat, high-sugar, highly processed foods characteristic of the Western diet.

11 Jan 2018

Study identifies enzyme that regulates inflammation and metabolism in fat tissue

The human body has two primary kinds of fat--white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered interest as a potential means of combating obesity.

11 Jan 2018

Patients with desmoplastic melanoma respond well to immunotherapy

Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas, such as the head and neck, and usually seen in older patients.

11 Jan 2018

Company-sponsored CRISPR clinical studies to begin in 2018

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research.

10 Jan 2018

Research contributes to better understanding of cancer cell regulation

A team of cancer researchers from the University of Liverpool, has made an important contribution to our understanding of cancer cell regulation which could better inform future cancer treatments.

10 Jan 2018

Researcher provides insight into how stress causes physical symptoms and disease

A Michigan State University researcher is providing new insight into how certain types of stress interact with immune cells and can regulate how these cells respond to allergens, ultimately causing physical symptoms and disease.

10 Jan 2018

Circadian rhythms could hold key to novel treatments for glioblastoma

Biological clocks throughout the body play a major role in human health and performance, from sleep and energy use to how food is metabolized and even stroke severity.

10 Jan 2018

Decorated cardiac stem cells could provide enhanced treatment for heart attacks

Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury - and getting them to stay there - remains challenging.

10 Jan 2018

Chronic exposure to arsenic may increase risk of diabetes, study reveals

A new study reports that chronic exposure to arsenic interferes with insulin secretion in the pancreas, which may increase the risk of diabetes.

10 Jan 2018

Researchers find evidence for genetic relationship between epileptic seizures and depression

From the time of Hippocrates, physicians have suspected a link between epilepsy and depression. Now, for the first time, scientists at Rutgers University-New Brunswick and Columbia University have found evidence that seizures and mood disorders such as depression may share the same genetic cause in some people with epilepsy, which may lead to better screening and treatment to improve patients' quality of life.

10 Jan 2018

Stress accelerates development of pancreatic cancer, study shows

A new study shows that stress accelerates the development of pancreatic cancer by triggering the release of "fight-or-flight" hormones. Beta-blockers--commonly used medications that inhibit these hormones--were found to increase survival in a mouse model of the disease.

10 Jan 2018

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the The American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

10 Jan 2018

Family study looks at potential genetic distinctions between bipolar disorder subtypes

The most common subtypes of bipolar disorder, bipolar I and bipolar II, stem-at least in part-from different biological causes, according to a new study published in Biological Psychiatry.

10 Jan 2018

Lack of sunlight may be to blame for winter weight gain

We may have a new reason, in addition to vitamin D generation, to bask in a little sunshine. A breakthrough study by University of Alberta researchers has shown the fat cells that lie just beneath our skin shrink when exposed to the blue light emitted by the sun.

10 Jan 2018