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Injections of hunger hormone blocker can halt typical weight gain in mice

Mayo Clinic scientists have shown that injections of a hunger hormone blocker in mice can halt the typical weight gain after dieting and help prevent rebound obesity in the long term. The research findings appear in the Proceedings of the National Academy of Sciences.

26 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Chagas disease is a potentially life-threatening illness caused by the parasite, Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking bugs that are commonly referred to as "kissing bugs" or "vampire bugs".

26 Sep 2017

Study: Gene linked to schizophrenia risk controls early neurodevelopment

A gene associated with the risk of schizophrenia regulates critical components of early brain development, according to a new study led by researchers from Penn State University.

26 Sep 2017

New pig model for stroke could accelerate drug discovery process

It is well-known in the medical field that the pig brain shares certain physiological and anatomical similarities with the human brain. So similar are the two that researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will provide essential preclinical data and speed the drug discovery process.

26 Sep 2017

Breakthrough research offers new insight into function of the brain's anterior cingulate cortex

After four years of lab testing and complex neuro-decoding, a research team led by UNLV psychology professor James Hyman has struck a major breakthrough that could open the floodgates for research into the anterior cingulate cortex, or ACC, and how human brains learn.

26 Sep 2017

Biomaterial-mediated growth factor delivery can restore perfusion of blood vessels in animal models

Ischemia is a serious medical condition in which the flow of blood and delivery of oxygen to tissues is restricted, thus resulting in pain, weakness, and more seriously, tissue and organ damage. Ischemia in muscle tissue, most commonly as a result of atherosclerosis, leads to life-threatening diseases like coronary artery disease and stroke, but also to chronic peripheral artery disease (PAD).

26 Sep 2017

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Pediatric researchers investigating the childhood cancer neuroblastoma have identified common gene variants that raise the risk of an aggressive form of that disease. The discovery may assist doctors in better diagnosing subtypes of neuroblastoma.

25 Sep 2017

Drug targeting approach could lead to improved therapies for immune-related diseases

A new technique that targets drugs to specific cells could lead to improved therapies for diseases caused by an overactive immune response.

25 Sep 2017

Treating cartilage grafts with bone marrow concentrate before joint replacement speeds recovery

Biologic joint restoration using donor tissue instead of traditional metal and plastic may be an option for active patients with joint defects. Although recovery from a biologic joint repair is typically longer than traditional replacement, successful biologic restoration allows patients to return to full activity. However, in some cases, the transplanted bone does not heal correctly.

25 Sep 2017

Long-lasting effects of traumatic childhood experiences may be due to impaired neural connections

Researchers from the McGill Group for Suicide Studies, based at the Douglas Mental Health University Institute and McGill University’s Department of Psychiatry, have just published research in the American Journal of Psychiatry that suggests that the long-lasting effects of traumatic childhood experiences, like severe abuse, may be due to an impaired structure and functioning of cells in the anterior cingulate cortex.

25 Sep 2017

Diet plus alcohol may play key role in liver injury development

A new study published in Alcohol and Alcoholism finds that mice bred to consume high amounts of alcohol, but controlled by diet, did not necessarily develop the most severe liver injuries, suggesting that diet may pay an important role in liver injury development.

25 Sep 2017

Metabolism can impact host's susceptibility to develop malaria

Researchers from Instituto de Medicina Molecular Lisboa have found that the host's susceptibility to develop malaria depends on his or her metabolic state, which can be easily manipulated through external stimuli such as dietary patterns.

25 Sep 2017

Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease

A study published in the journal Nature Neuroscience, from Nature publishing group, describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease.

25 Sep 2017

Study: Antibody neutralizes dengue and Zika virus in mice

Brazil and other areas hardest hit by the Zika virus – which can cause babies to be born with abnormally small heads – are also home to dengue virus, which is spread by the same mosquito species.

25 Sep 2017

Probiotic bacteria can change intestinal flora of patients with colon cancer, study finds

Living lactic acid bacteria, probiotics, can change the intestinal flora of patients with cancer of the colon. These are the findings of a study published in the journal BMJ Open Gastroenterology.

25 Sep 2017

New MRI contrast agent differentiates between aggressive and slow-growing breast cancers

A new magnetic resonance imaging (MRI) contrast agent being tested by researchers at Case Western Reserve University not only pinpoints breast cancers at early stages but differentiates between aggressive and slow-growing types.

25 Sep 2017

Mother's diet during pregnancy could affect brain reward circuitry of children

Researchers in France found that rats who ate a junk food diet during pregnancy had heavier pups that strongly preferred the taste of fat straight after weaning. While a balanced diet in childhood seemed to reduce the pups' desire for fat, they nevertheless showed altered brain reward circuitry into adulthood.

25 Sep 2017

Brain shapes normal body patterning much earlier than previously thought

The brain plays an active and essential role much earlier than previously thought, according to new research from Tufts University scientists which shows that long before movement or other behaviors occur, the brain of an embryonic frog influences muscle and nerve development and protects the embryo from agents that cause developmental defects.

25 Sep 2017

Study shows that the brain uses supramodality to estimate confidence in different senses

A series of experiments at EPFL provide conclusive evidence that the brain uses a single mechanism (supramodality) to estimate confidence in different senses such as audition, touch, or vision. The study is published in the Journal of Neuroscience.

25 Sep 2017

Medical Science News

Injections of hunger hormone blocker can halt typical weight gain in mice

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Study: Gene linked to schizophrenia risk controls early neurodevelopment

New pig model for stroke could accelerate drug discovery process

Breakthrough research offers new insight into function of the brain's anterior cingulate cortex

Biomaterial-mediated growth factor delivery can restore perfusion of blood vessels in animal models

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Drug targeting approach could lead to improved therapies for immune-related diseases

Treating cartilage grafts with bone marrow concentrate before joint replacement speeds recovery

Long-lasting effects of traumatic childhood experiences may be due to impaired neural connections

Diet plus alcohol may play key role in liver injury development

Metabolism can impact host's susceptibility to develop malaria

Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease

Study: Antibody neutralizes dengue and Zika virus in mice

Probiotic bacteria can change intestinal flora of patients with colon cancer, study finds

New MRI contrast agent differentiates between aggressive and slow-growing breast cancers

Mother's diet during pregnancy could affect brain reward circuitry of children

Brain shapes normal body patterning much earlier than previously thought

Study shows that the brain uses supramodality to estimate confidence in different senses

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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