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Study opens door to new approach for curing HIV infections

In findings that open the door to a completely different approach to curing HIV infections, scientists from the Florida campus of The Scripps Research Institute have for the first time shown that a novel compound effectively suppresses production of the virus in chronically infected cells, and prevents viral rebound, even when those infected cells are subjected to vigorous stimulation.

17 Oct 2017

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Cancer can most often be successfully treated when confined to one organ. But a greater challenge lies in treating cancer that has metastasized, or spread, from the primary tumor throughout the patient's body.

17 Oct 2017

Study could pave way for more effective cancer therapies

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism, which normally prevent an excessive immune response. Researchers at the University of Bonn have now been able to take off one of these brakes.

17 Oct 2017

Scientists discover how sugar fuels cancer growth

A nine-year research project looking at the link between sugar and cancer has led to an important breakthrough in cancer research.

17 Oct 2017

Study reveals link between cancer relapse and body’s immune system

Results from a new study conducted at the Institute of Cancer Research, London, suggests cancer cells that remain in the body after treatment, utilize the immune system of the body to wake themselves up and boost their growth.

17 Oct 2017

Timing is crucial for corticosteroids to aid healing of tendons

A corticosteroid can improve the healing of damaged tendons, but it must be given at the right time, according to a new study from Linköping University in Sweden. In rats, the tendon became twice as strong. The results are presented in the journal Scientific Reports.

17 Oct 2017

Zinc-binding plays key role in sensing and regulation of brain’s pH levels

Researchers in Oslo, Norway, have discovered that Zinc-binding plays an important role in the sensing and regulation of pH in the human brain. The findings come as one of the first studies that directly link Zinc-binding with bicarbonate transporters.

17 Oct 2017

UAB researchers report major advance in efforts to repair damaged heart after heart attack

University of Alabama at Birmingham biomedical engineers report a significant advance in efforts to repair a damaged heart after a heart attack, using grafted heart-muscle cells to create a repair patch.

17 Oct 2017

Study sheds new light on why autism is more common in boys

Researchers aiming to understand why autism spectrum disorders (ASD) are more common in boys have discovered differences in a brain signaling pathway involved in reward learning and motivation that make male mice more vulnerable to an autism-causing genetic glitch.

17 Oct 2017

Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic and pharmacological strategies that mitigate this defect.

17 Oct 2017

USC study reveals how schizophrenia has biological effect on the entire brain

Some 40 years since CT scans first revealed abnormalities in the brains of schizophrenia patients, international scientists say the disorder is a systemic disruption to the brain's entire communication system.

17 Oct 2017

Discovery may lead to new approach for treating MS

Around 2.5 million people are affected by the autoimmune disease Multiple Sclerosis (MS), the commonest central nervous system disease among young adults.

17 Oct 2017

Novel gene expression signature assay could help enhance lymphoma management

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer and the most frequently diagnosed non-Hodgkin lymphoma worldwide (nearly 40% of cases). Recent advancements indicate that both the prognosis and choice of treatment of DLBCL may depend on identifying its molecular subtype.

17 Oct 2017

CHOP researchers discover key differences among gene fusions in childhood brain tumors

Researchers investigating pediatric low-grade gliomas, the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.

17 Oct 2017

Dietary combination transforms lethal breast cancers into highly treatable form

Researchers at the University of Alabama at Birmingham have found a dietary combination that transforms the most lethal of all breast cancers into a highly treatable breast cancer.

17 Oct 2017

Scientists discover new non-genetic cause of resistance to anti-cancer therapies

The targeted anti-cancer therapies cetuximab and panitumumab are mainstays of treatment for advanced colorectal cancer, the second leading cause of cancer-related deaths in the United States.

16 Oct 2017

Findings reveal how seizures can have lasting detrimental effects on memory

Although it's been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer's disease, how this happens has been puzzling. In a study published in the journal Nature Medicine, a team of researchers reveals a mechanism that can explain how even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models.

16 Oct 2017

Stress may just as harmful to our body as bad diet, BYU study finds

We all know that a poor diet is unhealthy, but a new BYU study finds that stress may just as harmful to our bodies as a really bad diet.

16 Oct 2017

BU researcher wins NIH award for research on molecular mechanism of senile cardiac amyloidosis

Lawreen H. Connors, PhD, associate professor of pathology and laboratory medicine and biochemistry at Boston University School of Medicine, is the recipient of a National Institutes of Health High Priority, Short-Term Project Award, for her research "molecular mechanism of senile cardiac amyloidosis."

16 Oct 2017

Einstein scientists share $9 million NIH grant for longevity research

Scientists now believe that the Fountain of Youth flows from our genes, or at least from the genes of people who live healthy lives to age 100 or later.

16 Oct 2017