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Study links multiple sclerosis in children to abundance of specific gut bacteria

In a recent study, children with multiple sclerosis had differences in the abundance of specific gut bacteria than children without the disease. Certain types of bacteria were either more or less abundant in children with multiple sclerosis.

17 May 2016

Researchers reveal new mechanism that helps breast cancer cells engage MDSCs

Not every breast cancer tumor follows the same path to grow. Some tumors have the assistance of myeloid-derived suppressor cells (MDSCs), a diverse type of immune cell involved in the suppression of the body's response against tumors.

17 May 2016

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Researchers at Beth Israel Deaconess Medical Center have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus.

17 May 2016

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

With more than 36.9 million people infected globally, HIV continues to be a major public health issue. Those living with the virus are at an increased risk for other non-AIDS diseases, such as cardiovascular disease and cancer, and though it's not entirely clear why, this has been associated with inflammation and abnormal blood clotting.

13 May 2016

New optimised PCR tests for reliable diagnosis of Zika virus

DZIF scientists from the University of Bonn have shown that not all conventional Zika virus molecular diagnostic tests for are sufficiently reliable. They developed optimised assays and a control for quantifying viruses in blood and urine.

13 May 2016

Genes linked to educational attainment expressed in the brain during prenatal development

An international group of 253 scientists has conducted one of the largest genetic studies to date and identified 74 genetic variants that are associated with the years of formal education that an individual completes.

13 May 2016

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

In a pair of related studies, chemists from the Florida campus of The Scripps Research Institute (TSRI) have identified and designed dozens of molecular “warheads” that not only can detect a key biomarker of cancer, but also could be developed into a potent new class of drug candidates for a range of diseases.

13 May 2016

Researchers identify out of control immune system linked to neurodegenerative diseases

AN out of control immune system has been identified as a possible cause of neurodegenerative diseases such as Alzheimer’s.

13 May 2016

BioNano study describes use of Irys System with Illumina-based NGS methods to achieve high-quality genomic assemblies

BioNano Genomics, the leader in physical genome mapping, today announced publication of another study describing application of its next-generation mapping (NGM) technology as the critical component in achieving high-quality de novo human genome assemblies with unprecedented contiguity.

13 May 2016

Maternal stress, depression during pregnancy may activate protective mechanisms in infants

Maternal stress and depression during pregnancy may activate certain protective mechanisms in babies. Psychologists from the University of Basel together with international colleagues report that certain epigenetic adaptations in newborns suggest this conclusion.

13 May 2016

ISSCR releases updated guidelines for stem cell research, development of new therapies

The International Society for Stem Cell Research, the world's largest professional organization of stem cell scientists, today released newly updated guidelines for stem cell research and the development of new clinical therapies.

13 May 2016

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant.

13 May 2016

Researchers develop novel ss-siRNAs to turn off disease-related genes

Combining the therapeutic potential and advantages of existing oligonucleotide-based approaches to turn off disease-related genes, a type of single-stranded silencing RNAs (ss-siRNAs) has shown significantly improved potency and activity.

13 May 2016

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

Cancer researchers have identified a marker that shows up in a blood test that determines which patients with colorectal cancer that has spread would benefit from receiving the drug cetuximab.

13 May 2016

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.

13 May 2016

Genetic change to non-DNA structures in cell can cause cancer

A mutation that affects the proteins that package DNA--without changing the DNA itself--can cause a rare form of cancer, according to new findings in this week's Science from researchers at The Rockefeller University.

13 May 2016

Mosquito larvae carries Sindbis virus that can cause Ockelbo disease

After an outbreak of Ockelbo disease in northern Sweden in 2013, researchers at Umeå University were able to trace the virus to mosquitos in an area of Lövånger. In a new study, researchers have shown that mosquito larvae in the Västerbotten region also carry virus that can cause infectious disease. These include the Sindbis virus, which causes Ockelbo disease, which is associated with fever, rashes and prolonged joint pain.

13 May 2016

New way of understanding neurodegeneration may lead to novel treatments

University of Adelaide researchers have developed a new theory for the causes of dementia and other neurodegenerative diseases, involving an out-of-control immune system.

13 May 2016

MIT researchers test tiny origami robot that unfolds from swallowed capsule in simulated stomach

In experiments involving a simulation of the human esophagus and stomach, researchers at MIT, the University of Sheffield, and the Tokyo Institute of Technology have demonstrated a tiny origami robot that can unfold itself from a swallowed capsule and, steered by external magnetic fields, crawl across the stomach wall to remove a swallowed button battery or patch a wound.

13 May 2016

Researchers investigate effects of non-allergenic components of pollen on allergy sufferers

Up to now, research into pollen allergies has largely focused on allergens - those components of pollen that trigger hypersensitivity reactions. When it comes into contact with the nasal mucous membrane, however, pollen releases a host of other substances in addition to allergens.

13 May 2016

Medical Science News

Study links multiple sclerosis in children to abundance of specific gut bacteria

Researchers reveal new mechanism that helps breast cancer cells engage MDSCs

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

New optimised PCR tests for reliable diagnosis of Zika virus

Genes linked to educational attainment expressed in the brain during prenatal development

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

Researchers identify out of control immune system linked to neurodegenerative diseases

BioNano study describes use of Irys System with Illumina-based NGS methods to achieve high-quality genomic assemblies

Maternal stress, depression during pregnancy may activate protective mechanisms in infants

ISSCR releases updated guidelines for stem cell research, development of new therapies

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

Researchers develop novel ss-siRNAs to turn off disease-related genes

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Genetic change to non-DNA structures in cell can cause cancer

Mosquito larvae carries Sindbis virus that can cause Ockelbo disease

New way of understanding neurodegeneration may lead to novel treatments

MIT researchers test tiny origami robot that unfolds from swallowed capsule in simulated stomach

Researchers investigate effects of non-allergenic components of pollen on allergy sufferers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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